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2000 articles

October 202624

Clinical ResearchGeriatricsOpen access

Prevalence of fall risk and fear of falling among older adults in the Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated fall risk and fear of falling among adults aged 60 years or older in the Middle East and North Africa (MENA).

J Glob HealthOct 30, 2026Read summary
Case ReportOrthopedic SurgeryOpen access

Effect of Intravenous Acetaminophen on Preemptive Multimodal Analgesia for Pediatric Osteotomy Correction Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial.

Children undergoing Osteotomy correction surgery can experience substantial postoperative pain and frequently require opioids.

Drug Des Devel TherOct 30, 2026Read case
Clinical ResearchCardiology

Slow Flow/No-Reflow After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Meta-Analysis.

This meta-analysis synthesized clinical, laboratory, angiographic, and procedural factors associated with coronary slow flow/no-reflow after primary PCI for STEMI.

J Vis ExpOct 30, 2026Read summary
Clinical ResearchInfectious Diseases

Endpoint-specific mortality associated with malignancy among adults with sepsis or septic shock: a systematic review and meta-analysis.

This systematic review and meta-analysis examined mortality among adults with sepsis or septic shock, comparing patients with and without malignancy.

Ann MedOct 30, 2026Read summary
Case ReportPsychiatryOpen access

Lurasidone Induced Amphibian Like Buccal Oscillations: A Rare Case of Early Onset Tardive Dyskinesia Like Disorder in a Geriatric Patient with Treatment-Resistant Depression.

A 64-year-old woman with treatment-resistant depression developed floor-of-mouth movements resembling buccal pumping, along with white spots on the inner lower lip and facial puffiness, within 7 days of starting…

Psychopharmacol BullOct 30, 2026Read case
Clinical ResearchPulmonologyOpen access

The effect of propolis oral care on oral mucositis in intensive care patients with chronic obstructive pulmonary disease: a randomized controlled trial.

This randomized controlled trial evaluated whether adding propolis gargle to standard oral care prevented oral mucositis in 60 critically ill patients with chronic obstructive pulmonary disease.

Rev Assoc Med Bras (1992)Oct 30, 2026Read summary
Clinical ResearchPsychiatryOpen access

Dose-Dependent Effect of Crocin on Depressive and Anxiety Symptom Scores: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This GRADE-assessed systematic review and meta-analysis examined dose-response associations between crocin supplementation and depressive and anxiety symptom scores in 14 randomized controlled trials.

Depress AnxietyOct 30, 2026Read summary
Clinical ResearchGeriatrics

The Effects of Virtual Reality Group Reminiscence Therapy on Agitation, Cognition, Depression and Social Function in Patients With Alzheimer's Disease.

This assessor-blinded randomised controlled trial evaluated multisensory virtual reality group reminiscence therapy in 60 people with Alzheimer’s disease, comparing twice-weekly 40-minute sessions for 8 weeks with…

PsychogeriatricsOct 30, 2026Read summary
Case ReportPathology (Anatomic & Clinical)

Diagnosis and Surgical Management of a Solitary Fibrofatty Lesion of the Finger Mimicking Pachydermodactyly.

A 30-year-old man had progressive, painless enlargement around the proximal interphalangeal joint of his right middle finger after long-term repetitive mechanical stimulation.

J Vis ExpOct 30, 2026Read case
Clinical ResearchPsychiatry

Effects of psilocybin with psychological support on anhedonia in treatment-resistant depression: A randomized controlled pilot trial.

This randomized, double-blind, placebo-controlled pilot trial assessed psilocybin with psychological support for anhedonia in 20 participants with treatment-resistant major depressive disorder.

J Affect DisordOct 30, 2026Read summary
Case ReportNephrology

Acute kidney injury after aminoglycoside exposure in two cystic fibrosis patients receiving triple CFTR modulator therapy.

Two patients with cystic fibrosis developed acute kidney injury after their first aminoglycoside exposure while receiving triple CFTR modulator therapy.

J NephrolOct 30, 2026Read case
Clinical ResearchNephrology

Effects of a telehealth-supported home-based exercise program on functional capacity, sarcopenia risk, and patient-reported outcomes in non-dialysis stage 4-5 chronic kidney disease.

This prospective, parallel-group randomized controlled trial assessed a 12-week telehealth-supported home exercise program in adults aged ≥45 years with non-dialysis stage 4-5 chronic kidney disease.

J NephrolOct 30, 2026Read summary
Clinical ResearchNeurologyOpen access

First-in-Human Phase 1b/2a Trial Shows Safety with MEK 1/2 Inhibitor EDV2209 as A Novel Treatment for Spontaneous Subarachnoid Hemorrhage.

The STOP-DCI first-in-human Phase 1b/2a interventional, randomized, double-blind, placebo-controlled trial evaluated intracerebroventricular EDV2209, a MEK 1/2 inhibitor, in patients with severe spontaneous subarachnoid…

Transl Stroke ResOct 30, 2026Read summary
Case ReportNeurosurgeryOpen access

The paracondylar process: anatomical relationships and clinical implications.

A 55-year-old man with longstanding restricted neck movement, left-sided headaches and occasional dizziness underwent cervical CT.

Surg Radiol AnatOct 30, 2026Read case
Clinical ResearchInfectious Diseases

Second-hand smoke exposure linked to TB infection or disease in children/adolescents: systematic review and meta-analysis.

This PROSPERO-registered systematic review and meta-analysis examined observational evidence on household second-hand smoke (SHS) exposure and tuberculosis (TB) outcomes in children and adolescents aged 0–18 years in…

Int J Tuberc Lung DisOct 30, 2026Read summary
Case ReportPediatricsOpen access

Delayed Presentation of Neonatal Omphalitis with Suspected Invasive Soft-Tissue Infection and Late-Onset Sepsis Following Non-Sterile Home Delivery: A Case Report.

A 19-day-old girl presented with fever, poor feeding, abdominal distension, purulent umbilical discharge, periumbilical inflammation and necrotic-appearing tissue after a non-sterile home delivery and cord tying with…

Int Med Case Rep JOct 30, 2026Read case
Clinical ResearchInfectious Diseases

Factors associated with missed video directly observed therapy sessions among persons with TB.

This secondary analysis of the DOT Selfie randomised controlled trial in Uganda examined factors associated with missed video directly observed therapy (VDOT) submissions during TB treatment.

Int J Tuberc Lung DisOct 30, 2026Read summary
Case ReportDermatologyOpen access

Asymptomatic Tattoo-Associated Cutaneous Nontuberculous Mycobacterial Infection: Case Report.

An immunocompetent 28-year-old man presented with monomorphic papules bearing collarettes of scale, diffusely distributed but confined to recently tattooed skin.

JMIR DermatolOct 30, 2026Read case
Clinical ResearchOncology (Medical)

Phase 1 Study of Safety and PK With A Combination of Omeprazole and Trimetazidine for Fatty Acid Oxidation Inhibition in Patients With Advanced Solid Tumors.

This Phase I, open-label, 3 + 3 dose-escalation study assessed safety, tolerability, pharmacokinetics, and preliminary antitumor activity of once-daily oral omeprazole plus trimetazidine, two fatty acid oxidation…

Clin Transl SciOct 30, 2026Read summary
Clinical ResearchPediatricsOpen access

Nurse-Led treatment strategy based on asthma score and oxygen requirement in children with acute reversible bronchoconstriction: A randomised controlled non-inferiority trial.

This multicentre, open-label, randomised non-inferiority trial compared nurse-led treatment guided by the oxygen-adjusted Childhood Asthma Score (CAS O2) with the standard CAS protocol in children aged 2–18 years…

PLoS OneOct 30, 2026Read summary
Clinical ResearchNeurologyOpen access

The effect of acupuncture-rehabilitation therapy on brain functional plasticity in motor aphasia after ischemic stroke: a randomized clinical neuroimaging trial.

This randomized clinical neuroimaging trial assigned 26 patients with motor aphasia after ischemic stroke to conventional rehabilitation (CR) or CR plus acupuncture-rehabilitation (A-R); 26 healthy controls provided…

Brain Imaging BehavOct 30, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Community health worker intervention to prevent incident type 2 diabetes: A cluster randomized trial.

This pragmatic cluster-randomized controlled trial tested whether a 12-month community health worker (CHW) program could prevent type 2 diabetes in adults aged 18–75 years with prediabetes receiving care at two New York…

PLoS OneOct 30, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Associated factors for stress ulcers and gastrointestinal bleeding in patients with sepsis or septic shock: A systematic review.

This systematic review synthesized observational cohort and case-control studies of factors associated with stress ulcers or significant gastrointestinal bleeding in adults with sepsis or septic shock.

PLoS OneOct 30, 2026Read summary
Clinical ResearchPhysical Medicine & RehabilitationOpen access

Effects of a music-accompanied multimodal exercise program on trunk endurance, stress, and anxiety in university students: a randomized controlled trial.

This randomized controlled trial evaluated a 12-week, music-accompanied program combining core stabilization, diaphragmatic breathing, and relaxation in 80 university students assigned to intervention or waitlist…

Rev Assoc Med Bras (1992)Oct 30, 2026Read summary

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