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2000 articles

November 202624

Clinical ResearchOncology (Medical)

Sunlight Exposure and Breast Cancer Risk: A Systematic Review and Meta-analysis.

This systematic review and random-effects meta-analysis combined 31 epidemiologic studies to assess sunlight exposure and breast cancer incidence, subtype, and survival.

Cancer Epidemiol Biomarkers PrevNov 2, 2026Read summary
Clinical ResearchOphthalmologyOpen access

The risk of rhegmatogenous retinal detachment associated with topical pilocarpine: a systematic review.

This systematic review assessed whether topical pilocarpine is associated with rhegmatogenous retinal detachment (RRD) in patients aged 40 years or older, synthesising 10 comparative studies.

Int OphthalmolNov 2, 2026Read summary
Clinical ResearchNeurology

Microbiota-derived urolithins and cortical thickness in cognitively healthy older adults: a longitudinal MRI analysis of the WAHA trial.

This longitudinal MRI sub-study within the randomized WAHA trial examined whether changes in urinary microbiota-derived urolithins tracked with cortical-thickness changes in cognitively healthy older adults.

Food FunctNov 2, 2026Read summary
Clinical ResearchObstetrics & Gynecology

RELAX Perinatal Digital Intervention to Prevent Increasing Anxiety: A Randomized Clinical Trial.

This multisite, phase 2b randomized clinical trial tested whether a self-led, pregnancy-tailored digital cognitive bias modification intervention added to usual maternity care could prevent rising anxiety in pregnant…

JAMA Netw OpenNov 2, 2026Read summary
Clinical ResearchPsychiatry

A Scalable Teacher Professional Development and Wellness Program in Primary Schools: A Cluster Randomized Clinical Trial.

This cluster randomized clinical trial evaluated professional development (PD), with or without a teacher-wellness enhancement (PDT), in 47 urban and rural primary schools in Uganda.

JAMA Netw OpenNov 2, 2026Read summary
Clinical ResearchOncology (Medical)

Prognostic value of the systemic inflammation response index (SIRI) in glioma: A meta-analysis.

This meta-analysis assessed whether the systemic inflammation response index (SIRI) predicts outcomes in patients with glioma. It pooled evidence from eight retrospective cohort studies involving 1,778 patients.

PLoS OneNov 2, 2026Read summary
Case ReportAnesthesiology

Oral administration of parenteral S-ketamine in wound care when 'conventional' medication regimens are not sufficient: a case series.

A case series described four patients whose pain during wound care was not adequately controlled by conventional medication regimens.

J Wound CareNov 2, 2026Read case
Clinical ResearchOncology (Medical)Open access

Acceptability of a patient support and educational intervention for black breast cancer survivors.

This clinical trial evaluated the feasibility and acceptability of a six-week group support and education intervention for English-speaking Black women who had survived stage I–III breast cancer diagnosed within the…

Breast Cancer Res TreatNov 2, 2026Read summary
Case ReportInfectious Diseases

Tuberculous meningoencephalitis in a heart transplant recipient: a case report.

A 33-year-old heart transplant recipient receiving immunosuppression developed headache, fever, and focal neurological signs after a complicated admission that included an incidental miliary pulmonary pattern on chest…

Einstein (Sao Paulo)Nov 2, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Treatment of Small Peri-Implant Buccal Dehiscence Defects With SCTG or GBR: 3-Year Results of a Pilot Study.

This pilot randomized controlled trial compared subepithelial connective tissue grafting (SCTG) with guided bone regeneration (GBR) for small (≤ 3 mm) buccal bone dehiscences after single implant placement.

Clin Implant Dent Relat ResNov 2, 2026Read summary
Clinical ResearchEndocrinology

Effect of topical insulin in diabetic foot ulcer healing among patients with diabetes in Asia: a systematic review.

This systematic review assessed topical insulin for diabetic foot ulcer healing in patients with diabetes in Asian countries.

J Wound CareNov 2, 2026Read summary
Clinical ResearchUrologyOpen access

Tetracaine hydrochloride gel delays and reduces catheter-related bladder discomfort after transurethral resection: a randomized controlled trial.

This randomized, single-blind trial compared tetracaine hydrochloride gel with standard lubricant in 130 patients undergoing transurethral resection.

PeerJNov 2, 2026Read summary
Clinical ResearchPediatrics

Effects of bystander interventions on school bullying: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed school-based bystander interventions for bullying and cyberbullying among children and adolescents, drawing on 23 experimental and quasi-experimental controlled studies.

Rev Esc Enferm USPNov 2, 2026Read summary
Clinical ResearchOncology (Medical)

Primary Endocrine Therapy vs Upfront Surgery for Older Women With Estrogen Receptor-Positive Breast Cancer: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis compared primary endocrine therapy (pET) with upfront surgery for operable, nonmetastatic, estrogen receptor-positive breast cancer in older women.

JAMA Netw OpenNov 2, 2026Read summary
Clinical ResearchHematology

Phase 1/2 trial of Evomela for autologous transplant in myeloma: schedule optimization and matched comparison with MEL200.

This prospective, randomized phase 1/2 trial evaluated Evomela dose and infusion schedule in 60 patients with newly diagnosed multiple myeloma undergoing autologous stem cell transplantation.

Blood AdvNov 2, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Full-Service Mobile Food Markets and Dietary Quality in Low-Income Housing Communities: A Randomized Clinical Trial.

This cluster randomized clinical trial evaluated weekly full-service mobile market service at 12 subsidized housing sites in the Minneapolis–St. Paul area.

JAMA Netw OpenNov 2, 2026Read summary
Clinical ResearchCardiothoracic Surgery

Autologous Blood Pleurodesis for Postoperative Air Leakage Following Video-Assisted Thoracoscopic Surgery-A Randomized Controlled Trial.

This multicentre randomised controlled trial assessed early autologous blood pleurodesis (ABP) for postoperative air leakage after elective video-assisted thoracoscopic surgery.

Eur J Cardiothorac SurgNov 2, 2026Read summary
Clinical ResearchOphthalmology

Visual Perceptual Learning Based on Adaptive Contrast Detection Training Enhances Vision and Contrast Sensitivity in Diabetic Retinopathy.

This randomized controlled trial evaluated 3-month home-based visual perceptual learning (VPL) in people with diabetic retinopathy who had received routine therapies.

Invest Ophthalmol Vis SciNov 2, 2026Read summary
Clinical ResearchOncology (Medical)

Cost-Effectiveness of Remote Symptom Monitoring During Adjuvant Endocrine Therapy in Breast Cancer.

This economic evaluation used data from a randomized trial of adult women initiating adjuvant endocrine therapy for early-stage breast cancer, comparing remote symptom monitoring via an app, an app with tailored…

JAMA Netw OpenNov 2, 2026Read summary
Case ReportEndocrinology

Expanding the role of ivabradine in thyrotoxic crisis: a case report and Insights from the Literature.

A 39-year-old woman with alemtuzumab-induced Graves’ disease developed thyroid storm with persistent sinus tachycardia despite high-dose propranolol.

Einstein (Sao Paulo)Nov 2, 2026Read case
Clinical ResearchOncology (Medical)

Neoadjuvant Nivolumab plus Carboplatin and Paclitaxel in Patients with Locally Advanced Resectable Squamous Cell Carcinoma of the Head and Neck: A Phase II, Single-Arm Trial.

This single-arm, open-label phase II trial evaluated neoadjuvant nivolumab plus carboplatin and paclitaxel in patients with newly diagnosed, locally advanced, resectable head and neck squamous cell carcinoma, including…

Clin Cancer ResNov 2, 2026Read summary
Clinical ResearchEndocrinology

Adjunctive neodymium-doped yttrium aluminum garnet laser therapy for periodontitis in type 2 diabetes: A randomized controlled trial.

This randomized controlled trial compared conventional nonsurgical periodontal therapy with or without adjunctive neodymium-doped yttrium aluminum garnet laser therapy in 120 patients with periodontitis and type 2…

J Int Med ResNov 2, 2026Read summary
Case ReportEndocrinology

Tirzepatide-associated severe euvolemic hyponatremia with syndrome of inappropriate antidiuretic hormone secretion-compatible biochemical features.

A woman with type 2 diabetes and morbid obesity, taking regular insulin and chronic torsemide, developed anorexia, weakness, and drowsiness 10 days after receiving tirzepatide.

Indian J PharmacolNov 2, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

Associations of Health Literacy and eHealth Literacy With Patient Portal Access and Use: Systematic Review.

This systematic review synthesized quantitative studies of health literacy and eHealth literacy in relation to real-world patient portal access and use among adults.

JMIR Hum FactorsNov 2, 2026Read summary

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