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245 articles
November 202623
Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…
Effect of discontinuing antihypertensives on perioperative hypotension in older patients before non-cardiac surgery: multicentre, randomised, double blind, controlled trial.
This multicentre, randomised, double blind, placebo controlled trial assessed whether withholding ACE inhibitors or ARBs on the morning of surgery reduces perioperative hypotension in older adults undergoing non-cardiac…
Impact of artificial intelligence-assisted health management on blood pressure and self-management efficacy in older adults with hypertension.
This randomized controlled trial compared AI-assisted health management with routine care in older adults with hypertension. The intervention included intelligent monitoring, early warning and proactive intervention.
Operative versus nonoperative management of olecranon fractures in older adults: a systematic review and meta-analysis.
This systematic review and meta-analysis compared operative with nonoperative management of displaced olecranon fractures in older adults.
The Effect of Exercise Training on Individuals With Osteoporotic Vertebral Fracture: A Randomized Controlled Trial.
This single-centre, open-label randomised controlled trial evaluated a 12-week supervised exercise programme in adults with osteoporotic vertebral fractures.
Triple immune impairment in an elderly patient with IgG4-AIP and MGUS complicated by dual severe infections over 3 years: A case report.
An 82-year-old man with IgG4-related autoimmune pancreatitis and IgGλ monoclonal gammopathy of undetermined significance had markedly elevated serum IgG4 and a monoclonal paraprotein at baseline.
Effects of opioid-free and opioid-sparing anesthesia on postoperative delirium: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed opioid-free and opioid-sparing anesthesia for preventing postoperative delirium (POD) in adult surgical patients.
Effects of Tai Chi combined with repetitive transcranial magnetic stimulation on sleep and emotional outcomes in older adults: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis examined randomized controlled trials of combined Tai Chi and repetitive transcranial magnetic stimulation (rTMS) for sleep and emotional outcomes in older adults.
Severe Rosuvastatin-Associated Rhabdomyolysis and Dialysis-Requiring Acute Kidney Injury in an Octogenarian Patient: A Case Report.
An 87-year-old woman developed progressive weakness and inability to walk 20 days after starting rosuvastatin, ezetimibe, and evogliptin.
Impact of Particulate Matter Exposure on Neurological Health in Older Adults: A Systematic Review.
This PRISMA-guided systematic review assessed epidemiological evidence linking particulate matter (PM) exposure with neurological health in older adults.
Testing the EQ-HWB-9 with seven-day versus today recall periods in dementia: variability and recall adherence under health fluctuations.
This mixed-methods randomized study compared “7-day” and “today” EQ-HWB-9 recall periods in people living with dementia and caregiver dyads recruited from German primary care.
Feasibility and tolerability of combining 6 Hz transcranial alternating current stimulation (tACS) at 3.2 mA and digital cognitive training in older adults with mild cognitive impairment.
This randomized-trial study evaluated feasibility and tolerability of five daily sessions of 6-Hz, 3.2-mA transcranial alternating current stimulation (tACS) during digital cognitive training (DCT) in older adults with…
The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.
Risk factors for cognitive impairment in patients undergoing hemodialysis: an umbrella review and meta-analysis.
This umbrella review and meta-analysis examined factors associated with cognitive impairment and cognitive frailty in adults receiving maintenance hemodialysis. It included five meta-analyses covering 97 associations.
Effects of exercise interventions on leptin and ghrelin levels in middle-aged and older adults with overweight or obesity: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed randomized controlled trials of exercise interventions in middle-aged and older adults with overweight or obesity, examining changes in leptin and ghrelin.
Dapagliflozin attenuates progression from prefrailty to frailty in patients with hypertension and chronic kidney disease.
DAPA-FORTRESS followed prefrail hypertensive adults aged over 65 years with chronic kidney disease (CKD) for 1 year to examine links between renal measures and physical performance, and whether dapagliflozin was…
Primary Endocrine Therapy vs Upfront Surgery for Older Women With Estrogen Receptor-Positive Breast Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis compared primary endocrine therapy (pET) with upfront surgery for operable, nonmetastatic, estrogen receptor-positive breast cancer in older women.
Six-Month Music Practice Versus Psychomotor Interventions in Mild Cognitive Impairment: Behavioral and Hippocampal Outcomes.
This pilot randomized controlled intervention study compared six months of intensive musical instrument training with psychomotor interventions in people with mild cognitive impairment (MCI), using matched healthy…
Effect of Exercise Interventions on Sarcopenia-Related Outcomes in Older Adults With Type 2 Diabetes: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed structured exercise versus nonexercise control in adults with type 2 diabetes whose mean age was at least 65 years.
Evaluating the accuracy of brief cognitive assessments for the early detection of cognitive impairment in adults across primary and specialty care settings: A systematic review and meta-analysis.
This systematic review and meta-analysis assessed brief, freely available cognitive tests for detecting cognitive impairment, including mild cognitive impairment and dementia, in adults aged 55 years and older in…
Exercise and Nutritional Interventions for Muscle Strength, Physical Performance, and Body Composition Among Older Adults With Sarcopenia or Pre-Sarcopenia: A Network Meta-Analysis.
This network meta-analysis compared exercise, nutritional, and combined interventions with control strategies in older adults with sarcopenia or pre-sarcopenia.
Systematic Review of Smart Home Assistive Technology Devices for Supporting People With Dementia Living in Their Homes.
This systematic review and meta-analysis assessed smart home and wearable assistive technologies for people with dementia living at home or in supported accommodation.
Effects of Integrated Multicomponent Care on Older Adults With Frailty or Pre-Frailty: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed integrated multicomponent care (IMC) for older adults with frailty or pre-frailty, including evidence from 20 randomised and quasi-experimental studies.
October 20261
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