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2000 articles

October 202624

Clinical ResearchAnesthesiologyOpen access

Effect of a Subanesthetic Dose of Esketamine on Postoperative Sleep Disturbance After Oocyte Retrieval Under Intravenous Anesthesia: A Randomized Controlled Trial.

This randomized, double-blind, placebo-controlled trial assessed whether intravenous esketamine reduces postoperative sleep disturbance (PSD) in women undergoing oocyte retrieval with intravenous anesthesia.

Drug Des Devel TherOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Volumetric discordance between ¹⁸F-FET-PET/MRI and MRI-based radiotherapy target volumes in high-grade glioma: a prospective pilot study (FETSMaRT).

This prospective pilot study enrolled 30 patients with WHO grade 3 or 4 high-grade glioma receiving postoperative radiotherapy.

J NeurooncolOct 14, 2026Read summary
Case ReportNeurosurgery

Painless Spontaneous Spinal Epidural Hematoma Mimicking Acute Ischemic Stroke: A Case Report.

A woman in her early 60s receiving anticoagulant and antiplatelet therapy developed neck tightness and numbness in both limbs without pain, followed by transient right hemiplegia and rapid neurological deterioration.

Ann Ital ChirOct 14, 2026Read case
Clinical ResearchPlastic Surgery

Multiple-Staged Versus Single-Stage Surgical Excision for the Reconstruction of Congenital Melanocytic Nevi: A Meta-Analysis of Efficacy and Safety.

This meta-analysis compared multiple-staged with single-stage excision and reconstruction for congenital melanocytic nevi (CMN). It pooled seven retrospective cohort or clinical controlled studies involving 578 patients.

Ann Ital ChirOct 14, 2026Read summary
Case ReportOncology (Medical)

Recurrent Primary Angiosarcoma of the Breast: Challenges and Pitfalls in a Case Report.

A patient presented with a breast lesion and skin involvement; histopathology and immunohistochemistry confirmed low- to intermediate-grade primary breast angiosarcoma.

Ann Ital ChirOct 14, 2026Read case
Clinical ResearchGeneral SurgeryOpen access

Routine versus postoperative CRP/CT guided selective diverting ileostomy after laparoscopic low anterior resection for rectal cancer: a comparative randomized controlled trial.

This randomized controlled trial compared postoperative CRP/CT-guided selective diversion with routine diverting ileostomy in 200 patients with stage II or III middle or lower rectal cancer undergoing laparoscopic low…

BMC SurgOct 14, 2026Read summary
Clinical ResearchDermatologyOpen access

Outcomes and Predictors of Sustained Response After Dose Tapering of Targeted Therapies in Moderate-to-Severe Atopic Dermatitis: A Systematic Review.

This systematic review examined dose tapering or withdrawal of biologics and small-molecule inhibitors in moderate-to-severe atopic dermatitis (AD), including 19 studies and 4375 patients.

Am J Clin DermatolOct 14, 2026Read summary
Case ReportCardiology

Integrated Use of Extracorporeal Membrane Oxygenation and Molecular Adsorbent Recirculating System for Refractory Cardiotoxic Ingestion: A Single-Center Case Series.

Five consecutive patients with severe calcium-channel blocker or beta-adrenergic antagonist ingestions developed profound hypotension and respiratory failure despite standard therapies.

Crit Care ExplorOct 14, 2026Read case
Clinical ResearchCardiology

Efficacy and Safety of Enlicitide in Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and random-effects meta-analysis assessed efficacy and safety of oral enlicitide in adults with hypercholesterolemia.

Endocrinol Diabetes MetabOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Immune biomarkers of response and resistance to ipilimumab and nivolumab in metastatic castration-resistant prostate cancer.

The multicenter phase II AMADEUS prostate expansion cohort evaluated escalating ipilimumab doses with nivolumab in 32 patients with metastatic castration-resistant prostate cancer, assessing disease control, tumoral CD8…

Sci AdvOct 14, 2026Read summary
Case ReportMedical GeneticsOpen access

Severe growth retardation in Dent disease: a case report of a novel OCRL variant.

A 12-year-old boy with marked short stature and poor weight gain had low-molecular-weight proteinuria, haematuria, hypercalciuria and bilateral nephrocalcinosis, with normal renal function and no relevant family…

CEN Case RepOct 14, 2026Read case
Case ReportNeurology

A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings.

A 35-year-old woman with multiple sclerosis developed an enlarging thalamic lesion. Although new or enlarging lesions in MS can indicate disease activity, the lesion was ultimately diagnosed as a diffuse midline glioma…

Neurol Neuroimmunol NeuroinflammOct 14, 2026Read case
Clinical ResearchGastroenterology

Patient-reported and caregiver-reported outcomes in refractory ascites secondary to cirrhosis: A systematic review and meta-analysis.

This systematic review and meta-analysis examined patient- and caregiver-reported outcomes in refractory ascites (RA) secondary to advanced chronic liver disease.

Hepatol CommunOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

A comprehensive review of European clinical practice guidelines on psychological and cognitive assessment and support for cancer patients and their families.

This systematic review mapped European clinical practice guidelines and recommendations published in the preceding 15 years on psychological and cognitive assessment and support for people with cancer and their…

Support Care CancerOct 14, 2026Read summary
Clinical ResearchOncology (Medical)

Impact of body composition on clinical outcomes in patients with hepatocellular carcinoma: A systematic review and meta-analysis.

This systematic review and meta-analysis examined associations between body composition and outcomes in patients with hepatocellular carcinoma (HCC), across curative, locoregional, systemic, and mixed treatment…

Hepatol CommunOct 14, 2026Read summary
Case ReportDermatologyOpen access

Exploring the landscape of flagellate erythema as a rare cutaneous symptom of idiopathic inflammatory myopathy: a case series-based review.

Two patients with idiopathic inflammatory myopathy developed zebra-like flagellate erythema: one had immune-mediated necrotising myopathy and the other anti-Mi-2-positive cancer-associated myositis.

Rheumatol IntOct 14, 2026Read case
Clinical ResearchOncology (Medical)

Dietary and lifestyle quality and endometrial cancer: Incidence and survivorship outcomes-An umbrella review of systematic reviews and meta-analyses.

This umbrella review of 21 systematic reviews, including meta-analyses, assessed composite diet and lifestyle quality in relation to endometrial cancer (EC) risk and survivorship outcomes.

PLoS OneOct 14, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Anxiety in patients with cancer and emergency department use: a systematic review.

This systematic review examined whether anxiety is associated with subsequent emergency department (ED) use among adults with cancer.

Support Care CancerOct 14, 2026Read summary
Clinical ResearchAnesthesiologyOpen access

Perineural versus intravenous dexmedetomidine as an adjuvant for ilioinguinal/iliohypogastric nerve block in open inguinal hernia repair: a randomised controlled trial.

This single-centre, triple-blind randomised controlled trial compared perineural, intravenous and placebo dexmedetomidine as adjuncts to an ilioinguinal/iliohypogastric nerve block in 90 adults undergoing elective open…

HerniaOct 14, 2026Read summary
Case ReportCardiology

Case Report: Veno-Arteriovenous Extracorporeal Membrane Oxygenation for Management of Pheochromocytoma-Induced Cardiac Arrest in a Post-Partum Patient.

A 34-year-old woman, two days postpartum, was admitted to intensive care with hypertensive crisis and respiratory failure. CT showed an 18-cm left adrenal mass suspicious for pheochromocytoma.

A A PractOct 14, 2026Read case
Case ReportAnesthesiology

Preoperative Sedation via Cecostomy Tube in an Autistic Adolescent: A Case Report.

A 13-year-old autistic boy with a preexisting cecostomy tube for chronic constipation had previously been unable to tolerate oral or intramuscular preoperative sedation because of agitation and physical aggression.

A A PractOct 14, 2026Read case
Clinical ResearchCardiologyOpen access

Ramadan Fasting in Chronic Heart Failure: A Systematic Review.

This systematic review assessed clinical studies of Ramadan fasting in people with chronic heart failure. Searches of PubMed, Scopus, and Web of Science identified seven eligible studies from 137 records; most were…

Curr Cardiol RepOct 14, 2026Read summary
Case ReportOphthalmologyOpen access

Orbitocranial resection for treatment of lacrimal gland malignant tumors with intracranial extension.

Two patients with malignant lacrimal gland tumors extending intracranially underwent multidisciplinary orbitocranial resection, followed by postoperative chemoradiotherapy.

Braz J OtorhinolaryngolOct 14, 2026Read case
Case ReportMedical Genetics

Aberrant splicing caused by a homozygous AK2 c.498 + 1G > A variant in a patient with reticular dysgenesis and concurrent B-cell acute lymphoblastic leukemia.

A boy with reticular dysgenesis (RD), a severe immunodeficiency associated with biallelic AK2 loss of function, was also diagnosed with B-cell acute lymphoblastic leukemia (B-ALL).

GeneOct 14, 2026Read case

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