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2000 articles
November 202624
Molecular Diagnostics and Clinicopathologic Spectrum of Kinase Fusion-Positive Spindle Cell Neoplasms of the Oral and Maxillofacial Region: A Systematic Review and Pooled Patient-Level Analysis.
This systematic review and pooled patient-level analysis characterized kinase fusion-positive spindle cell neoplasms of the oral and maxillofacial region using published reports.
The characteristics of men who have sex with men presenting with oral syphilis: a systematic review.
This systematic review described demographic, behavioural, co-infection and clinical features of men who have sex with men (MSM) presenting with oral syphilis.
Evening amber-lensed glasses in combination with a prescribed wake time advance circadian timing in adolescents with delayed sleep-wake phase disorder.
This 3-week randomized controlled trial tested evening amber-lensed glasses plus a prescribed stable wake time in adolescents aged 14.3–18.1 years with delayed sleep-wake phase disorder (DSWPD).
Multiorgan [ 18 F]florbetapir PET/CT uptake in multiple myeloma-associated systemic AL amyloidosis: a case report.
A 77-year-old man with multiple myeloma underwent whole-body [18F]florbetapir PET/CT because AL amyloidosis was suspected. The scan showed prominent tracer retention in the myocardium, thyroid, lungs, parotid glands…
Impact of artificial intelligence-assisted health management on blood pressure and self-management efficacy in older adults with hypertension.
This randomized controlled trial compared AI-assisted health management with routine care in older adults with hypertension. The intervention included intelligent monitoring, early warning and proactive intervention.
Barriers and facilitators to HPV vaccination among adult men: A systematic review and qualitative meta-synthesis.
This qualitative systematic review and meta-synthesis examined barriers and facilitators to HPV vaccination among adult men and how healthcare services address vaccination needs.
Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.
This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…
Intractable Nausea and Vomiting: A Key Feature of Neuromyelitis Optica Spectrum Disorder.
A 22-year-old woman had five weeks of intractable nausea, vomiting, and hiccups. Delayed gastric emptying led to an initial diagnosis of gastroparesis, but symptoms persisted despite antiemetic and prokinetic therapy.
Dose-dense neoadjuvant bi-weekly nab-paclitaxel followed by epirubicin-cyclophosphamide versus bi-weekly docetaxel followed by epirubicin-cyclophosphamide in patients with HR+/HER2- early breast cancer: a multicentre, randomised, phase III trial.
This multicentre, randomised phase III trial at three hospitals in China compared dose-dense neoadjuvant nab-paclitaxel with docetaxel, each followed by epirubicin-cyclophosphamide, in patients with early HR+/HER2−…
Operative versus nonoperative management of olecranon fractures in older adults: a systematic review and meta-analysis.
This systematic review and meta-analysis compared operative with nonoperative management of displaced olecranon fractures in older adults.
Machine Learning Models for Glycemic Prediction in Type 1 and Type 2 Diabetes: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed machine-learning models predicting glucose values or glycemic events in people with type 1, type 2, mixed, or unclear diabetes.
Individualizing Apheresis Processing Volumes Using a Predictive Algorithm: Analysis of the CAR T-Cell Collection Protocol Utilized in ACIT001/EXC002, a Phase Ib/II Trial of Decentralized Production of CAR T Cells for Treatment of Relapsed/Refractory Aggressive NHL and ALL.
This analysis of the CAR T-cell collection protocol used in the phase Ib/II ACIT001/EXC002 trial examined individualized blood-volume processing for patients with relapsed or refractory non-Hodgkin lymphoma or acute…
Dose-specific effects of caffeinated chewing gum on reactive blocking timing, jump mechanics, and neuromuscular responses after volleyball-specific fatigue in elite female volleyball players.
This randomized, double-blind, placebo-controlled crossover study examined caffeinated chewing gum in 15 elite female volleyball players after a volleyball-specific repeated-blocking fatigue protocol.
Surgical outcomes and functional morbidity after retrosigmoid/retrocondylar and midline suboccipital approaches for foramen magnum meningiomas: a single-arm meta-analysis.
This PRISMA-guided systematic review and single-arm meta-analysis assessed surgical control and functional morbidity after posterior or posterolateral approaches for foramen magnum meningiomas.
Prosthesis-Patient Mismatch and Patient-Centered Outcomes After TAVR.
This post hoc analysis of the multicentre SCOPE I randomised trial examined whether prosthesis-patient mismatch (PPM) severity after transcatheter aortic valve replacement was associated with survival and…
Prolonged exposure, eye movement desensitization and reprocessing therapy, and cognitive restructuring versus waiting-list for individuals with PTSD and psychosis (RE.PROCESS): A multicenter, four-arm, assessor-masked, superiority randomized controlled trial.
The multicenter, assessor-masked RE.PROCESS randomized controlled trial compared Prolonged Exposure (PE), eye movement desensitization and reprocessing (EMDR), and Cognitive Restructuring (CR), each alongside usual…
Simultaneous Infection Control and Reconstruction Using Continuous Local Antibiotic Perfusion in Septic Knee With Extensive Soft Tissue Defect: A Case Report.
A 69-year-old woman presented 2.5 months after patellar fracture fixation with methicillin-resistant Staphylococcus aureus infection, septic knee arthritis, and a 12×8 cm anterior soft tissue defect with joint exposure.
Association of HTR3A and COMT polymorphisms with electroacupuncture response for chemotherapy-induced nausea and vomiting in breast cancer: a secondary analysis of a randomized controlled trial.
This exploratory, treatment-stratified secondary analysis of a randomized controlled trial examined whether three HTR3A and COMT polymorphisms were associated with complete protection (CP) against chemotherapy-induced…
Altered effective connectivity during cognitive distancing in cognitive behavioral therapy nonresponders with depression.
This clinical trial analysis examined whether pretreatment brain connectivity during cognitive distancing was associated with cognitive behavioral therapy (CBT) response in 77 outpatients with major depressive disorder.
Multifocal intradural extramedullary myxopapillary ependymoma of the spine.
A 34-year-old man presented with sudden severe non-radicular low-back pain but no neurological deficit. MRI showed multiple enhancing intradural extramedullary lesions from T12-L1 to S1; the dominant T12-L1 lesion…
Clinical Reasoning: A 33-Year-Old Man With Rapidly Progressive Ataxia.
A 33-year-old man with AIDS developed subacute progressive confusion, blurred vision, diplopia, and generalized cerebellar ataxia after hospitalizations for opportunistic infections.
Sex Differences in Blood Pressure Dynamics and Outcomes After Endovascular Thrombectomy.
This exploratory secondary analysis of the multicenter, open-label, blinded-end-point ENCHANTED2/MT randomized trial examined sex differences in blood pressure (BP) and outcomes among adults with acute ischemic stroke…
Clinical Reasoning: A 69-Year-Old Female Patient With Rapid-Onset Levodopa-Responsive Rest Tremor, Parkinsonism, and Gait Freezing.
A 69-year-old woman developed a unilateral resting tremor that rapidly spread to the opposite arm and then the legs. Within 3 months, she had generalized parkinsonism, a shuffling gait with prominent freezing, and…
Short-term outcomes of the hinotori versus da Vinci robotic surgical systems in colorectal cancer surgery: a systematic review and meta-analysis.
This systematic review and meta-analysis compared short-term perioperative outcomes of hinotori and da Vinci robotic systems in colorectal cancer surgery.
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