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2000 articles
November 202624
Testing the Impact of the #Chatsafe Intervention on Young People's Ability to Communicate Safely About Suicide on Social Media: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether #chatsafe social media content improved safe online communication about suicide among young people aged 16–25 years.
Cannula exchange for refractory cannula infections during Berlin Heart EXCOR support: a case report.
A 4-year-old girl with truncus arteriosus and severe heart failure received Berlin Heart EXCOR (BHE) support after complex cardiac surgery.
Comparative Efficacy of Different Biologic Agents on Radiographic Progression in Patients with Rheumatoid Arthritis: A Network Meta-Analysis.
This Bayesian random-effects network meta-analysis compared six biologic DMARD classes for radiographic progression in rheumatoid arthritis, using randomized controlled trials and change in modified Total Sharp Score…
A nurse-coordinated intervention programme vs standard of care after an acute coronary syndrome: the ALLEPRE trial.
The multicentre, pragmatic, randomized ALLEPRE trial compared a nurse-coordinated prevention programme with hospital standard care in patients recovering from acute coronary syndrome.
Effectiveness of guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism): a randomized controlled trial.
This randomized controlled trial evaluated a 5-week, guided internet-delivered cognitive behavioral therapy intervention adapted for autistic adults with insomnia.
Non-invasive vascular assessment in gestational hypertension and preeclampsia during pregnancy and the postpartum period: a systematic review.
This systematic review evaluated non-invasive measures of vascular structure and function in women with gestational hypertension or preeclampsia during pregnancy and postpartum.
Impact of early versus delayed mobilization after arthroscopic rotator cuff repair in small and medium-sized tears: a prospective randomized study.
This prospective randomized study compared early with delayed mobilization after arthroscopic single-row knotless repair of small and medium full-thickness supraspinatus tears in 70 patients aged 20–70 years.
Feasibility of robotic-assisted surgery for nutcracker syndrome: a systematic review and single-arm meta-analysis.
This systematic review and single-arm meta-analysis assessed robotic-assisted surgery for nutcracker syndrome (NCS), using 10 studies of 140 patients, mostly retrospective case series.
Impact of nasogastric administration using the simple suspension method on serum tirabrutinib levels: A case report.
An 82-year-old man with relapsed primary central nervous system lymphoma began tirabrutinib at 320 mg/day while fasting. As dysphagia progressed, administration changed from swallowing tablets to nasogastric delivery by…
Efficacy and safety of apixaban versus rivaroxaban in acute venous thromboembolism: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis compared apixaban with rivaroxaban for acute venous thromboembolism in adults.
Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.
Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…
Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.
This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.
Oliceridine vs Sufentanil Combined With Ondansetron for Postoperative Nausea and Vomiting and QTc Interval in Hysteroscopic Surgery: A Prospective Randomized Controlled Study.
This prospective, randomized, double-blind controlled study compared oliceridine plus ondansetron with sufentanil plus ondansetron in 62 patients undergoing non-intubated hysteroscopic surgery under general anesthesia.
Dirozalkib versus Crizotinib in Advanced Anaplastic Lymphoma Kinase Inhibitor-Naïve ALK -Positive Non-Small-Cell Lung Cancer: A Multicenter, Randomized Phase III Trial.
DIAMOND-2 was a multicenter, randomized, open-label phase III trial comparing dirozalkib with crizotinib in adults with ALK inhibitor-naïve, ALK-positive advanced non-small-cell lung cancer.
Combined Immunotherapy and Hybrid Dose-Fraction Radiotherapy for Driver-Negative Metastatic NSCLC: A Phase II Trial with Parallel Preclinical Studies.
This single-arm, multicenter phase II trial evaluated hybrid dose-fraction radiotherapy added during first-line chemoimmunotherapy maintenance in 83 patients with stage IV driver-negative metastatic NSCLC.
Efficacy of De-Epithelialized vs. Subepithelial Grafts in Periodontal Plastic Surgery for Gingival Recession: A Systematic Review and Meta-Analysis of Root Coverage Techniques.
This systematic review and meta-analysis compared de-epithelialized gingival grafts (DGG) with subepithelial connective tissue grafts (SCTG) for RT1 gingival recessions.
Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial.
This prospective, multicentre, randomised, open-label non-inferiority trial compared prophylactic SynFlow 3.0 micro-axial flow pump support with VA-ECMO during non-emergent high-risk PCI in patients with complex…
Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.
This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.
Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.
This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…
Outcomes with Catheter-Directed Thrombolysis versus Mechanical Thrombectomy for Patients with Intermediate/High Risk Pulmonary Embolism: A Meta-Analysis of 24,090 Patients.
This meta-analysis compared catheter-directed thrombolysis (CDT) with mechanical thrombectomy (MT) in patients with intermediate- or high-risk pulmonary embolism treated with catheter-based therapies.
Spatial transcriptomics tumor microenvironment determinants of tyrosine kinase inhibitor response in renal cell carcinoma: results from a phase 2 clinical trial.
This phase 2 clinical trial examined whether spatially resolved tumor gene-expression patterns were associated with sunitinib response in 46 patients with metastatic clear cell renal cell carcinoma.
Physiological prehabilitation for patients undergoing cellular therapy in multiple myeloma and lymphoma: a systematic review.
This systematic review examined exercise-based physiological prehabilitation in adults with multiple myeloma or lymphoma before cellular or immune-based therapy.
Cardiovascular outcomes of glucagon-like peptide-1 receptor agonists: A systematic review.
This systematic review evaluated 12 cardiovascular outcome-based randomised controlled trials of GLP-1 receptor agonists (GLP1RAs): 10 in people with type 2 diabetes (T2D), one in people with overweight or obesity and…
Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.
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