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2000 articles

November 202616

Clinical ResearchObstetrics & GynecologyOpen access

Clinical outcomes and euploidy rates of embryos derived from zygotes with nonpronuclear (0PN) and monopronuclear (1PN) in IVF or ICSI cycles: a systematic review and meta-analysis.

This systematic review and meta-analysis compared euploidy and clinical outcomes for embryos derived from 0PN or 1PN zygotes with those from normally fertilized 2PN zygotes in IVF/ICSI cycles.

Hum Reprod UpdateNov 1, 2026Read summary
Clinical ResearchEndocrinology

Effectiveness of Traditional Chinese Fitness Methods on Depressive Symptoms and Glycaemic Control in Patients With Type 2 Diabetes and Comorbid Depression: A Systematic Review and Meta-Analysis of Taijiquan and Baduanjin.

This systematic review and meta-analysis assessed randomised controlled trials of Taijiquan and Baduanjin in people with type 2 diabetes and comorbid depression. Eight trials, all conducted in China, were included.

Endocrinol Diabetes MetabNov 1, 2026Read summary
Case ReportInfectious Diseases

Mycobacterium abscessus bacteremia: A narrative literature review based on a case report.

The report describes a catheter-associated bloodstream infection caused by Mycobacterium abscessus subsp. massiliense. The authors also reviewed published M.

Enferm Infecc Microbiol Clin (Engl Ed)Nov 1, 2026Read case
Clinical ResearchGastroenterology

Compositional, Spatial and Functional Changes Occur Within Bacteria Associated With Precancerous Colonic Lesions: A Systematic Review.

This systematic review examined human studies comparing gut microbiota in people with colorectal polyps and healthy controls defined by normal colonoscopy.

APMISNov 1, 2026Read summary
Case ReportObstetrics & Gynecology

Cesarean Delivery After Multiple Prior Intraperitoneal Surgeries: A Case Report in a Patient With Crohn Disease.

A 25-year-old woman with Crohn disease in sustained remission had an uncomplicated pregnancy after in vitro fertilization. Her history included five intraperitoneal operations, including bilateral hemicolectomy…

Am J Case RepNov 1, 2026Read case
Case ReportOncology (Medical)Open access

Preoperative Temporal Elevation of Cytokeratin 19 Fragment in Thymoma With Extensive Necrosis: A Case Report.

A 73-year-old man presented with chest pain, and CT showed a mediastinal mass with pleural effusion. White blood cell count, C-reactive protein, and cytokeratin 19 fragment (CYFRA) were elevated; CYFRA was 61.3 ng/mL.

Thorac CancerNov 1, 2026Read case
Case ReportHematology

A Triad of Hematologic Diseases in a Military Member Requiring Splenectomy Case Report.

An active-duty servicemember with hereditary spherocytosis, sickle cell trait, and Factor VII deficiency developed recurrent, worsening pain crises after flights.

Mil MedNov 1, 2026Read case
Case ReportPhysical Medicine & Rehabilitation

Upweighting Proprioceptive Information for Treatment of Mal de Mer: A Case Report.

A 46-year-old woman aboard a U.S. Navy ship developed severe dizziness that prevented unsupported walking and substantially limited computer work.

Mil MedNov 1, 2026Read case
Case ReportOtolaryngology (ENT)

Aberrant Internal Carotid Artery: A Rare Cause of Unfitness Revealed During Admission Audiometry.

A 23-year-old woman undergoing medical assessment for army enlistment was found on audiometry to have unilateral conductive hearing loss. Otoscopy showed a pale red, pulsatile middle-ear mass anterior to the umbo.

Mil MedNov 1, 2026Read case
Clinical ResearchNeurology

The shared genetic architecture of the TDP-43 spectrum: Bridging clinical FTLD and neuropathological endophenotypes.

This inverse-variance fixed-effects and random-effects meta-analysis examined shared genetic associations across neuropathological TDP-43 conditions and clinically diagnosed frontotemporal lobar degeneration (FTLD).

Alzheimers DementNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Short-Term Pain Outcomes of Trigger Point Injection Versus Dry Needling for Acute Myofascial Low Back Pain in the Emergency Department: A Prospective Randomized Comparative Study.

This prospective randomized comparative study evaluated trigger point injection versus dry needling for acute myofascial low back pain in emergency department patients.

Med Sci MonitNov 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Biomarker Modulation by Aspirin and Metformin for Colorectal Cancer Prevention: Results from the ASAMET Randomized Phase II Trial.

The multicenter, double-blind, 2 × 2 factorial phase II ASAMET randomized trial evaluated aspirin, metformin, and their combination for 12 months in patients with resected stage I to III colorectal cancer.

Cancer Res CommunNov 1, 2026Read summary
Clinical ResearchOphthalmology

First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.

This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…

J Extracell VesiclesNov 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

Effects of Exercise Type and Duration on Pain, Function, and Quality of Life in Patients With Knee Osteoarthritis: A Systematic Review With Bayesian Network Meta-Analysis.

This systematic review with Bayesian network meta-analysis compared aerobic, resistance, and combined exercise for pain, function, and quality of life in people with knee osteoarthritis.

J Orthop Sports Phys TherNov 1, 2026Read summary
Clinical ResearchOncology (Medical)

Immune Checkpoint Inhibitor Rechallenge After Immune-Related Adverse Events: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis pooled observational cohort evidence on restarting immune checkpoint inhibitors (ICIs) after treatment interruption for an immune-related adverse event (irAE).

Cancer MedNov 1, 2026Read summary
Clinical ResearchEndocrinology

Prevalence of Diabetes in Low- and Middle-Income Countries' Incarcerated Populations: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis estimated diabetes prevalence among incarcerated people in low- and middle-income countries (LMICs), drawing on 23 studies with 107,473 participants.

Endocrinol Diabetes MetabNov 1, 2026Read summary

October 20268

Case ReportPediatricsOpen access

Solitary Neurofibroma in the Submental Region of a 15-Year-Old Adolescent: A Case Report and Review of Literature.

A 15-year-old boy had a painless right submental swelling present for one year, with enlargement over the preceding three months.

Int Med Case Rep JOct 31, 2026Read case
Case ReportCardiology

Unveiling Asymptomatic Atrioventricular Reciprocating Tachycardia in a Patient With Wolff-Parkinson-White Syndrome and Multiple Sclerosis.

A 54-year-old woman with secondary-progressive multiple sclerosis was admitted with a complicated urinary tract infection. Her initial ECG showed sinus tachycardia without preexcitation, but telemetry captured a…

Am J Case RepOct 31, 2026Read case
Case ReportRheumatologyOpen access

Severe ARDS and secondary haemophagocytic lymphohistiocytosis complicating a flare of adult-onset Still's disease: a case-based review.

A 42-year-old woman with adult-onset Still’s disease (AOSD) developed a flare after a five-week interruption of conventional synthetic disease-modifying therapy around surgery for a perianal abscess with fistulous…

Rheumatol IntOct 31, 2026Read case
Clinical ResearchInternal Medicine (General)

The experience of family caregivers when their loved one is home hospitalized: a mixed methods analysis of a randomized controlled trial.

This mixed-methods analysis examined family caregivers of patients in a multicentre randomised controlled trial of rural home hospital care in the USA and Canada.

Age AgeingOct 31, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Glycemic control and weight loss benefits of fixed-ratio combinations of basal insulins and GLP1 receptor agonists in type 2 diabetes: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared fixed-ratio combinations of basal insulin and GLP-1 receptor agonists with basal insulin alone in adults with type 2 diabetes.

EndocrineOct 31, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Early functional deterioration during first-line ICI-based therapy in advanced NSCLC: implications for supportive care.

This secondary exploratory analysis of prospectively collected data from a randomized pulmonary rehabilitation trial assessed early functional change in 42 people receiving first-line immune checkpoint inhibitor–based…

Support Care CancerOct 31, 2026Read summary
Clinical ResearchPsychiatry

Effect of electroconvulsive therapy on anhedonia in adults with major depressive disorder: A systematic review and meta-analysis.

This systematic review and meta-analysis examined changes in anhedonia among adults with major depressive disorder treated with electroconvulsive therapy (ECT).

J Affect DisordOct 31, 2026Read summary
Clinical ResearchOncology (Medical)

Local ablative treatment for oligoprogression during immunotherapy in metastatic non-small-cell lung cancer: a systematic review and meta-analysis.

This PRISMA-compliant systematic review and meta-analysis assessed local ablative treatment (LAT), with continuation of the same immune checkpoint inhibitor, for oligoprogressive or oligo-resistant metastatic NSCLC…

OncoimmunologyOct 31, 2026Read summary

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