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2000 articles
November 202624
The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.
This phase III, single-centre randomised non-inferiority trial compared two sequential corifollitropin alfa (CFA) injections with conventional CFA followed by recombinant FSH in women undergoing elective fertility…
Pump-Predicted Ciprofol Ce50 for Suppressing the Cardiovascular Response to Tracheal Intubation During Fixed Sufentanil-Esketamine Induction: An Age-Stratified Dixon Up-and-Down Study.
To estimate the ciprofol pump-predicted effect-site target concentration associated with a 50% probability of suppressing the cardiovascular response to tracheal intubation (Ce50) during fixed sufentanil-esketamine…
Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.
This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…
Digital reminder systems for improving adherence to anti-rabies vaccination among animal bite victims: A systematic review.
This systematic review assessed whether digital reminders improve adherence to and completion of anti-rabies vaccination among animal-bite patients.
Effects of Physical Activity Interventions on Body Composition in Korean Students With Intellectual Disabilities: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed physical activity interventions and body composition in students with intellectual disabilities in Korea.
Effect of Food on the Pharmacokinetics, Pharmacodynamics, and Safety of Zastaprazan, a Potassium-Competitive Acid Blocker, in Healthy Participants.
This randomized, open-label, two-period crossover phase 1 study assessed food effects on zastaprazan pharmacokinetics, pharmacodynamics, and safety in 24 healthy participants given a single 20 mg dose.
Severe Infection Outcomes With SGLT2 Versus DPP-4 Inhibitors in Type 2 Diabetes: A Systematic Review and Active-Comparator Meta-Analysis of Real-World Cohorts.
This systematic review and active-comparator meta-analysis examined real-world severe infection outcomes among people with type 2 diabetes treated with SGLT2 inhibitors versus DPP-4 inhibitors.
Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.
A comparison of the efficacy and safety of direct oral anticoagulants with low molecular weight heparin for venous thromboembolism prophylaxis after total hip arthroplasty : a systematic review and meta-analysis.
This systematic review and meta-analysis compared direct oral anticoagulants (DOACs) with low molecular weight heparin (LMWH) for venous thromboembolism prophylaxis after elective total hip arthroplasty.
Streptozotocin-based chemotherapy in advanced PanNETs: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed objective response and progression-free survival with streptozotocin (STZ)-containing chemotherapy in advanced pancreatic neuroendocrine tumours.
Exercise and Nutritional Interventions for Muscle Strength, Physical Performance, and Body Composition Among Older Adults With Sarcopenia or Pre-Sarcopenia: A Network Meta-Analysis.
This network meta-analysis compared exercise, nutritional, and combined interventions with control strategies in older adults with sarcopenia or pre-sarcopenia.
Ascites Presenting as a Peritonitis-Like Manifestation and Liver Injury due to Trabectedin Monotherapy in a Patient With Myxoid Liposarcoma.
An 82-year-old woman with recurrent metastatic myxoid liposarcoma developed liver dysfunction and ascites while receiving trabectedin monotherapy, after 12 cycles.
Effects of a Nurse-Led Multicomponent Exercise Intervention for Haemodialysis Patients With Possible or Confirmed Sarcopenia: A Cluster Randomised Trial.
This cluster randomised trial evaluated a 12-week nurse-led multicomponent exercise programme in haemodialysis patients with possible or confirmed sarcopenia.
A multicenter, prospective, phase 2 trial on proton re-irradiation for patients with previously treated head and neck cancer.
This multicenter, prospective phase 2 trial evaluated proton re-irradiation in patients with previously irradiated head and neck cancer.
Structural Brain Correlates of Bulimia Nervosa Diagnosis and Symptom Severity: A Coordinated ENIGMA Eating Disorders Working Group Analysis.
This coordinated, international case-control meta-analysis examined structural MRI correlates of bulimia nervosa (BN) diagnosis and symptom severity across 17 cohorts at 13 sites.
Clindamycin and bacterial load reduction as prophylaxis for surgical site infection after below-knee flap and graft procedures.
This randomised controlled trial evaluated clindamycin prophylaxis and preoperative chlorhexidine washing in consecutive patients undergoing below-knee flap or graft procedures.
Long-Term Marginal Bone Stability of BOPT Restorations on Bone-Level vs. Tissue-Level Implants: An 8-Year Prospective Clinical Study.
This prospective randomized clinical study compared eight-year marginal bone loss in 122 posterior bone-level and tissue-level implants restored using the Biologically Oriented Preparation Technique (BOPT) in 71…
Artificial Intelligence for Assessing the Relationship Between Mandibular Third Molars and the Inferior Alveolar Nerve on Panoramic Radiographs: A Systematic Review.
This systematic review assessed artificial intelligence (AI) models that use panoramic radiographs to evaluate the relationship between mandibular third molars and the inferior alveolar nerve, with cone-beam computed…
Dual Remission of Atopic Dermatitis and Frequently Relapsing Nephrotic Syndrome With Dupilumab.
A 9-year-old girl had atopic dermatitis and frequently relapsing, steroid-sensitive nephrotic syndrome, with relapses increasing despite treatment with two immunosuppressants.
Airway occlusions to measure inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation.
This multicenter randomized study assessed whether airway occlusion maneuvers can estimate inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation (NIV).
Biologics and small molecules for perianal Crohn's disease: a systematic review and meta-analyses of randomized placebo-controlled trials.
This systematic review and meta-analysis pooled placebo-controlled randomized trials of advanced therapies for perianal fistulizing Crohn’s disease.
Interventions to Support Parents Whose Babies Cry Excessively: Systematic Review.
This systematic review and meta-analysis assessed comparative studies of interventions supporting parents of babies aged ≤1 year with excessive crying.
Supervised physiotherapeutic scoliosis-specific exercises provide limited additional benefit at 24 months in braced adolescents with idiopathic scoliosis: a randomized trial.
This randomized trial compared supervised Schroth-based physiotherapeutic scoliosis-specific exercises (PSSE) with self-directed general exercise in adolescents with idiopathic scoliosis receiving brace treatment.
Can Clinicians Predict Which Patients Respond Best to a Specific Treatment? A Systematic Review of Low Back Pain Moderators in Primary Care.
This systematic review synthesized randomized trials and secondary analyses examining whether patient characteristics modify responses to primary care interventions for nonspecific low back pain.
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