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2000 articles

November 202624

Clinical ResearchPediatrics

Efficacy of Manual Physiotherapy Techniques for Improving Cervical Range of Motion in Infants With Congenital Muscular Torticollis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed therapist-directed manual physiotherapy techniques for cervical range of motion (ROM) in infants with congenital muscular torticollis.

Physiother Res IntNov 7, 2026Read summary
Case ReportOncology (Medical)

Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.

A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.

Neuropathol Appl NeurobiolNov 7, 2026Read case
Case ReportPediatrics

Intestinal tuberculosis with multiple intestinal perforations in a 5-month-old infant: The role of metagenomic next-generation sequencing: a case report and literature review.

A 5-month-old boy presented with fever and abdominal distension that progressed to intestinal obstruction and multiple perforations involving the distal ileum and appendiceal region.

Medicine (Baltimore)Nov 6, 2026Read case
Clinical ResearchPreventive Medicine / Public Health

Firearm Injury Prevention Bystander Intervention for Adolescents in Shooting Sports: A Cluster Randomized Clinical Trial.

This parallel cluster randomized clinical trial evaluated a 3-session, co-developed firearm injury prevention bystander curriculum among adolescents in US 4-H Shooting Sports clubs.

JAMA Health ForumNov 6, 2026Read summary
Clinical ResearchPathology (Anatomic & Clinical)

Curriculum-Aligned Conversational AI to Support Pathology Self-Directed Learning in Preclinical Medical Students: Crossover Randomized Pilot Study.

This crossover randomized pilot study evaluated a curriculum-aligned custom GPT for self-directed pathology learning among 44 second-year medical students at the University of South Carolina, Floyd School of Medicine.

JMIR Med EducNov 6, 2026Read summary
Case ReportHematology

Assay-aware flow-cytometric interpretation of relapsed B-cell precursor acute lymphoblastic leukemia after sequential CD19- and CD22-directed therapy: A case report.

A 73-year-old woman with B-cell precursor acute lymphoblastic leukemia developed marrow relapse after blinatumomab exposure.

Medicine (Baltimore)Nov 6, 2026Read case
Case ReportRheumatology

Bone marrow sarcoidosis in Takayasu arteritis: Case report and literature review.

A 46-year-old woman with confirmed Takayasu arteritis presented with elevated systemic inflammatory markers and diffuse hypermetabolic activity on PET.

Medicine (Baltimore)Nov 6, 2026Read case
Clinical ResearchCardiology

Mitral regurgitation and all-cause mortality in acute heart failure: a meta-analysis.

This meta-analysis examined the association between mitral regurgitation (MR) and all-cause mortality in acute heart failure (AHF), pooling 27 studies with 73 363 patients and an average follow-up of 1.9 years.

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchCardiology

Differential rates of guideline-directed medical therapy modification in C-MIC and control patients: results from the C-MIC II trial.

This analysis of the multicentre, randomised C-MIC II trial examined whether changes in background heart failure medication influenced outcomes in ambulatory patients with chronic non-ischaemic HFrEF receiving…

ESC Heart FailNov 6, 2026Read summary
Clinical ResearchFamily MedicineOpen access

Cost-effectiveness of digital health in primary care: a systematic review.

This systematic review examined the cost-effectiveness of digital health interventions compared with usual care among adults receiving primary care.

BMC Health Serv ResNov 6, 2026Read summary
Case ReportAnesthesiologyOpen access

Esketamine-Based Versus Sevoflurane-Based Anesthesia with Dexmedetomidine for Emergence Agitation in Pediatric Corneal Suture Removal: A Randomised Controlled Trial.

Corneal suture removal, particularly microsurgery requiring complete immobility, demands adequate anesthetic depth while ensuring rapid recovery.

Drug Des Devel TherNov 6, 2026Read case
Case ReportMedical Genetics

Allan-Herndon-Dudley syndrome associated with SLC16A2 c.1384G>A (p.Gly462Arg): A family case report with retrospective molecular diagnosis in a deceased sibling.

A boy evaluated at 4.3 years had profound developmental delay, abnormal tone, dystonia, muscle atrophy, contractures, and bilateral cryptorchidism.

Medicine (Baltimore)Nov 6, 2026Read case
Clinical ResearchNeurologyOpen access

Impact of Particulate Matter Exposure on Neurological Health in Older Adults: A Systematic Review.

This PRISMA-guided systematic review assessed epidemiological evidence linking particulate matter (PM) exposure with neurological health in older adults.

Curr Environ Health RepNov 6, 2026Read summary
Clinical ResearchOncology (Medical)

Comparative efficacy and safety of second- and later-line BRAF-targeted regimens in BRAF V600E-mutant metastatic colorectal cancer: A systematic review and network meta-analysis.

This systematic review and network meta-analysis compared the efficacy and safety of second- and later-line BRAF-targeted regimens in adults with BRAF V600E-mutant metastatic colorectal cancer.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchEndocrinology

Oral Acarbose Inhibits Baseline Salivary Amylase and Blunts Early Postprandial Glycemia: Randomized Cross-Over Study.

This single-blinded, placebo-controlled randomized cross-over trial examined whether oral acarbose inhibition of salivary α-amylase affects postprandial blood glucose in 15 young, healthy women.

JMIR Form ResNov 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Intra-arterial tenecteplase for acute basilar artery occlusion with sufficient recanalization after thrombectomy: the INSIST-IT randomized clinical trial.

The INSIST-IT multicentre, prospective, randomised trial assessed adjunctive intra-arterial tenecteplase after successful endovascular reperfusion in patients with acute basilar artery occlusion treated within 24 hours…

Nat CommunNov 6, 2026Read summary
Clinical ResearchPediatrics

Effects of a parenting and unconditional cash transfer intervention on child development and maternal well-being in urban Bangladesh: medium-term follow-up of a cluster randomised controlled trial.

This medium-term follow-up of a cluster randomised controlled trial in Rangpur, Bangladesh, compared parenting plus unconditional cash transfers with cash transfers alone.

J Glob HealthNov 6, 2026Read summary
Clinical ResearchPulmonologyOpen access

Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed mucus-plug prevalence, clinical characteristics and outcomes across chronic respiratory diseases, including asthma, COPD and cystic fibrosis.

LungNov 6, 2026Read summary
Clinical ResearchNeurologyOpen access

Subsequent epilepsy surgery after SEEG-guided radiofrequency thermocoagulation: Outcomes and prognostic value of treatment response-a systematic review and meta-analysis.

This systematic review and meta-analysis assessed outcomes after resective, disconnective, or ablative epilepsy surgery in patients previously treated with SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC), and…

Neurosurg RevNov 6, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Effects and safety of Korean red ginseng on the clinical course of uterine leiomyoma: A double-blind randomized placebo-controlled trial.

This single-center, double-blind randomized placebo-controlled trial assessed Korean red ginseng (KRG) in premenopausal women with uterine leiomyoma managed expectantly.

Medicine (Baltimore)Nov 6, 2026Read summary
Case ReportNeurosurgeryOpen access

When a glabellar dermoid cyst is not the whole story: the significance of MRI in excluding intracranial segments.

A 14-month-old boy underwent removal of a glabellar dermoid cyst considered extracranial. He remained asymptomatic, but surveillance MRI 10 months later showed a right frontal parasagittal intracranial lesion…

BMC PediatrNov 6, 2026Read case
Clinical ResearchUrology

Peptides for male sexual dysfunction: a systematic review of emerging evidence.

This PRISMA-guided systematic review assessed human studies of peptide-based therapies for male sexual function, reproductive hormones, and semen parameters.

J Sex MedNov 6, 2026Read summary
Case ReportCardiology

Left Ventricular Free-Wall Injury During Emergency Pericardial Drainage After Percutaneous Coronary Intervention-Related Coronary Perforation.

A 63-year-old woman developed shock and an enlarging pericardial effusion after PCI for a severely calcified right coronary artery lesion complicated by perforation, which was sealed with a covered stent.

Am J Case RepNov 6, 2026Read case
Clinical ResearchPediatrics

Effect of a dietary behaviour change education intervention on iron status and linear growth in children aged 6 to 59 months: a cluster-randomised controlled trial in rural Ethiopia.

This cluster-randomised controlled trial evaluated community-based Dietary Intake Behaviour Education (DIBE) among children aged 6–59 months in rural central Ethiopia.

Prim Health Care Res DevNov 6, 2026Read summary

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