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2000 articles
October 202624
Miro1 mediates skeletal muscle insulin resistance in type 2 diabetes.
This study investigated whether mitochondrial Rho GTPase 1 (Miro1) contributes to skeletal muscle insulin resistance in type 2 diabetes (T2D).
Technological Integration in Triage With AI and Machine Learning Compared With Conventional Triage and Narrative Synthesis of Telehealth for Patient Prioritization in Emergency and Acute Care Settings: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed AI- and machine-learning-assisted triage alongside tele-triage and digital tools in emergency and acute care.
Paediatric Helicobacter pylori infection and allergic and inflammatory diseases: a contemporary systematic review with meta-analysis.
This systematic review and meta-analysis assessed recent evidence on Helicobacter pylori infection and allergic or immune-mediated diseases in children.
AI-Based Clinical Decision Support Systems in Primary Care: Systematic Review of Clinical Implementation.
This systematic review assessed the effectiveness and safety of AI-based clinical decision support systems (AI-CDSSs) used by health professionals in primary care, compared with usual care or non-AI decision support.
Association of continuous glucose monitoring metrics with cardiovascular and kidney outcomes in type 2 diabetes: Data from the GRADE-CGM substudy.
This analysis of the GRADE-CGM substudy examined whether blinded continuous glucose monitoring (CGM) metrics were associated with cardiovascular events or death and kidney function decline in 1,363 people with type 2…
Cardiac Effects of Combined Versus Individual Interventions of Mediterranean Diet and Exercise in Adults with the Hypertriglyceridemic Waist Phenotype: A Randomized Trial.
This randomized 2 × 2 factorial trial assessed whether a Mediterranean diet and structured exercise, alone or combined, affected echocardiographic left ventricular (LV) structure and function in adults with the…
A process evaluation of community-led distribution of HIV self-testing kits in rural communities in Zimbabwe.
This process evaluation examined community-led HIV self-testing (HIVST) distribution in rural Zimbabwe, within the community-led arm of a cluster-randomized trial comparing it with paid, community-based distribution.
Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial.
This exploratory secondary analysis of a 12-week randomized controlled trial examined behavioral engagement with smartphone cognitive behavioral therapy for obsessive compulsive disorder (OCD) in 60 participants.
Effectiveness of physical, psychological, and alternative interventions for post-COVID-19 condition: a systematic review.
This systematic review of randomized controlled trials assessed supervised, face-to-face non-pharmacological interventions in adults with WHO-defined post-COVID-19 condition.
Oral mucous membrane pemphigoid as a window to systemic autoimmunity: two cases associated with rheumatoid arthritis and Sjögren's disease.
Two women presented with oral mucous membrane pemphigoid (MMP) in the setting of systemic autoimmunity. A 68-year-old woman with longstanding rheumatoid arthritis had recurrent oral ulcerations confirmed as MMP on…
Relationship between Vitamin D Status and the Risk of Obesity without Diagnosed Metabolic Syndrome: A Meta-Analysis of Observational Studies.
This systematic review and meta-analysis pooled observational studies examining vitamin D status and obesity without diagnosed metabolic syndrome.
Long-term efficacy of lebrikizumab in treating head, neck and face involvement in patients with moderate-to-severe atopic dermatitis.
This post hoc analysis of phase III trials assessed head, neck, and face (HNF) outcomes with lebrikizumab in adolescents and adults with moderate-to-severe atopic dermatitis.
High-Resolution Ultrasound in the Evaluation of Median and Superficial Radial Nerve Involvement in Neurofibromatosis Type 1.
A 16-year-old girl with neurofibromatosis type 1 presented with hand pain and paresthesia. High-resolution ultrasound showed a hypervascular superficial neurofibroma, marked epineural thickening of the median nerve…
POCUS Image Archiving in Emergency Medicine: A Systematic Review of Clinical and Financial Impacts.
This systematic review assessed clinical, operational, and financial outcomes of archiving point-of-care ultrasound (POCUS) images in electronic health records in emergency departments.
Evaluating the impact of conditional micro-incentives on linkage to HIV care in rural South Africa: results from the Home-Based Intervention to Test and Start (HITS) trial.
The HITS real-world randomized trial assessed whether conditional food vouchers improved linkage to HIV care after home-based testing in rural KwaZulu-Natal, South Africa.
Pacak-Zhuang syndrome with EPAS1 p.Pro531Leu somatic variant: one case report and literature review.
A 4-year-old girl presented with recurrent hypertension, polycythemia and renal hilar masses. Imaging, biochemical testing and genetic analysis of paraffin-embedded tissue confirmed Pacak-Zhuang syndrome with a somatic…
Robotic resection of cardiac papillary fibroelastoma guided by three-dimensional transesophageal echocardiography: a case report.
A patient was diagnosed with a papillary fibroelastoma involving the mitral valve. Three-dimensional transesophageal echocardiography (3D TEE) was used to characterize the suspected lesion and assess its anatomy…
An Integrated Approach to MSI-High Colorectal Cancer Therapy in a Young Patient: A Clinical Case.
A 16-year-old male underwent appendectomy for presumed appendicitis, but persistent postoperative bowel obstruction led to CT detection of a descending-colon tumor and emergency Hartmann’s procedure.
Magnetic resonance imaging vs computed tomography for baseline imaging evaluation in acute basilar artery occlusion.
This post hoc analysis of the ATTENTION trial compared baseline MRI with CT for patient selection in acute basilar-artery occlusion.
Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.
This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…
Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects.
This open-label, randomized, single-dose, three-period crossover study compared the pharmacokinetics and safety of 20 mg zastaprazan orally disintegrating tablets (ODTs), taken with or without water, with the…
Hepatitis A Virus (HAV) Recurrence and De Novo Hepatitis A Acquired at Time of Liver Transplantation: Comparison of Graft HAV Infection and Viral Kinetics.
Two liver transplant recipients developed hepatitis A virus (HAV) infection of the graft in different settings. A recipient transplanted for HAV-related acute liver failure had a rapid fall in serum HAV RNA after…
The Impact of Anaesthesia Method on the Use of Anaesthesia Department Resources in Total Knee Arthroplasty.
This randomised controlled trial compared spinal anaesthesia with general anaesthesia using total intravenous anaesthesia in 395 patients undergoing total knee arthroplasty.
Advances in physiotherapy for chronic low-back pain: a level I systematic review.
This level I systematic review qualitatively examined randomised controlled trials of physiotherapy programmes for chronic low-back pain (cLBP), identified through searches of PubMed, Web of Science and Embase in August…
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