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2000 articles
October 202624
Evaluation of the Achievement of a Pharmacodynamic Target of Piperacillin-Tazobactam for the Population With Obesity: An Open Randomized Controlled Feasibility Study (TAZO-OBESITY Trial).
The open-label randomized feasibility trial TAZO-OBESITY compared standard with prolonged piperacillin-tazobactam infusions in patients with obesity (BMI ≥30 kg/m²).
Pulmonary infection caused by Nocardia cyriacigeorgica and influenza A virus coinfection in an immunocompetent patient: A case report.
A 60-year-old immunocompetent man without reported underlying pulmonary disease presented with recurrent cough and sputum production over 5 months, worsening respiratory symptoms, and recent fever.
Ravulizumab in IgA Nephropathy - Interim Analysis of a Phase 3 Trial.
This phase 3, multicenter, randomized, placebo-controlled trial evaluated intravenous ravulizumab every 8 weeks in adults with IgA nephropathy and persistent proteinuria despite standard therapy.
Vulvar infection caused by Histoplasma capsulatum: case report and literature review.
A 38-year-old woman with advanced HIV infection presented with a vulvar lesion suggestive of carcinoma. Histopathology, fungal culture and molecular testing confirmed vulvar infection with Histoplasma capsulatum var.
The entorhinal cortex atrophy score for diagnostic distinction between phases of the Alzheimer's disease continuum.
This systematic review assessed the Entorhinal Cortex Atrophy (ERICA) visual score for distinguishing subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer’s disease (AD) dementia.
Robotic Totally Intracorporeal Bilateral Boari Flap Reconstruction for Complex Bilateral Ureteral Strictures: A Step-by-Step Technique.
A 42-year-old woman with complex bilateral mid- and distal ureteral strictures underwent robotic, totally intracorporeal bilateral Boari flap reconstruction.
Robot-Assisted Radical Prostatectomy in a Post-Enucleation Gland.
A 64-year-old man was found to have right-lobe ISUP grade 3 prostate adenocarcinoma after HoLEP for benign prostatic obstruction. PSA was 0.51 ng/mL, and MRI showed a 0.4 cm PI-RADS 4 lesion.
Efficacy and safety of GLP-1 receptor agonists in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH): A systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed efficacy and safety of GLP-1 receptor agonists in adults with MASLD or MASH. Nine studies involving 795 participants were included.
A Methodological Framework for a Large Language Model Virtual Companion for Older Adults at Risk of Social Isolation.
This paper presents a methodological framework for developing and evaluating a large language model (LLM)-driven virtual companion for older adults at risk of social isolation.
Evaluation of Acute Electrical and Hemodynamic Improvement During Left Bundle-Branch Area Pacing Modalities for Resynchronization Therapy.
This prospective, within-subject physiological study assessed acute electrical and hemodynamic responses to four pacing modalities in 24 patients with heart failure with reduced ejection fraction and left bundle-branch…
Fosfomycin-induced liver injury in a 17-year-old patient: A case report.
A previously healthy 17-year-old male developed nausea, vomiting, fever, progressive epigastric pain, fatigue, and malaise.
Fatal Occupational Leptospirosis in a Beef Cattle Farmer: Case Report and Epidemiological Investigation.
A 56-year-old beef cattle farmer in Lombardy, Italy, died from occupational leptospirosis. Testing identified a strain of serogroup Javanica, with a microscopic agglutination test titre of 1:3,200 against serovar Poi.
Interim Analysis of a Phase 3 Trial of Povetacicept in IgA Nephropathy.
This prespecified interim analysis of an ongoing, multicenter, phase 3 randomized, double-blind, placebo-controlled trial evaluated povetacicept in participants with biopsy-proven IgA nephropathy receiving stable…
Role of Plasma Proteins in the Association Between Socioeconomic Status and Cardiovascular Disease Events: Results From Trans-Omics for Precision Medicine Cohorts.
This meta-analysis examined socioeconomic status (SES), plasma proteins, and incident coronary heart disease (CHD) and stroke in participants from three cohorts.
Intra-Arterial Alteplase After Successful Endovascular Reperfusion in Patients Without Intravenous Thrombolysis: A Subgroup Analysis of the PEARL Randomized Clinical Trial.
This prespecified subgroup analysis of the multicenter, randomized PEARL trial examined adjunctive intra-arterial alteplase after successful endovascular thrombectomy in patients with large-vessel occlusion stroke who…
Perineal Urethrostomy After Urethral Stricture: Step-by-Step Surgical Technique.
A 73-year-old man with complex, recurrent urethral stricture after multiple reconstructive and endoscopic procedures underwent perineal urethrostomy. His history also included Bowen’s disease of the glans penis.
Anatomopathological Aspects and Clinical Correlation of Conjunctival Bleb Fibrosis Following Encapsulation of a Biodegradable Collagen Matrix Implant in Glaucoma Surgery.
Four patients with progressive glaucoma and inadequate intraocular pressure control despite maximal medical therapy underwent non-penetrating deep sclerectomy with a biodegradable collagen-glycosaminoglycan implant and…
Adjunctive Oliceridine During Propofol or Ciprofol Sedation for Same-Session Bidirectional Endoscopy in Older Adults: A Multicenter Randomized 2×2 Factorial Trial.
This multicenter, double-blind, placebo-controlled 2×2 factorial randomized trial assessed adjunctive oliceridine with propofol or ciprofol for same-session bidirectional endoscopy in adults aged 65–80 years.
Jidesheng Snake Pills as Adjunctive Therapy for Snakebite: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and meta-analysis assessed randomized evidence for Jidesheng Snake Pills as adjunctive treatment for snakebite. Five unique trials involving 458 participants were included.
Streptococcus constellatus-Associated Lemierre Syndrome Presenting With Cavitating Septic Pulmonary Emboli Managed by Video-Assisted Thoracoscopy.
A previously healthy 25-year-old man presented with a week of dyspnea, productive cough, fever, and hemoptysis, with severe hypoxemia and respiratory distress.
Effects of E-Coach-Based Chronic Disease Management on Self-Management, Quality of Life, and Mental Health in Maintenance Hemodialysis Patients.
This randomized controlled trial evaluated a WeChat-based E-Coach programme in 96 patients receiving maintenance hemodialysis, comparing usual care plus E-Coach with usual care alone.
Extending the Graft Harvesting Area in Severe Penoscrotal Hypospadias: The Rainbow Technique.
A 2-year-old with severe penoscrotal hypospadias, a scrotal meatus, bifid scrotum, and chordee exceeding 90° underwent first-stage reconstruction.
Low-Dose Epidural Hydromorphone as an Adjunct to Ropivacaine for Intraoperative Visceral Traction Pain During Elective Cesarean Delivery: A Randomized, Double-Blind, Placebo-Controlled Trial.
Visceral traction during cesarean delivery may cause pain, nausea, and autonomic activation despite an adequate neuraxial block.
Simple Site, Serious Sequelae: Septic Emboli from a Peripheral Cannula.
A young woman developed right arm pain and pleuritic chest pain after a recent hospitalisation, with marked inflammation (CRP 296 mg/L, WCC 13.7 ×10⁹/L).
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