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2000 articles

November 202624

Case ReportAnesthesiology

Arterial-to-End-Tidal CO₂ Gradient Direction as a Differential Diagnostic Clue During Sudden Hypercapnia in Thoracoscopic Surgery with Capnothorax: A Report of 2 Cases.

Two men undergoing thoracoscopic surgery with CO₂ insufflation developed abrupt rises in end-tidal CO₂ (EtCO₂). In the first, the rise coincided with severe hypotension and bradycardia; arterial blood gas showed PaCO₂…

Am J Case RepNov 10, 2026Read case
Clinical ResearchCardiology

Outcomes in the BETAMI-DANBLOCK trial compared with a Norwegian nationwide myocardial infarction population.

This transportability analysis compared participants in the BETAMI and DANBLOCK randomized trials with revascularized Norwegian patients who had myocardial infarction, LVEF ≥40%, and no heart failure.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchUrologyOpen access

Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.

This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…

World J UrolNov 10, 2026Read summary
Clinical ResearchNeurology

Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.

NeurologyNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Impact of early versus delayed mobilization after arthroscopic rotator cuff repair in small and medium-sized tears: a prospective randomized study.

This prospective randomized study compared early with delayed mobilization after arthroscopic single-row knotless repair of small and medium full-thickness supraspinatus tears in 70 patients aged 20–70 years.

J Orthop Surg ResNov 10, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

What Cochlear Implantation with Attempted Hearing Preservation in Widened Vestibular Aqueduct Adds to Understanding About the Etiology and Pathogenesis of Hearing Loss: A Systematic Review.

This PRISMA-compliant systematic review examined hearing preservation cochlear implantation in children with widened vestibular aqueduct (WVA), a congenital inner-ear malformation associated with childhood sensorineural…

J Int Adv OtolNov 10, 2026Read summary
Clinical ResearchCardiology

Micro-axial flow pump vs veno-arterial extracorporeal membrane oxygenation for high-risk percutaneous coronary interventions: a randomized trial.

This prospective, multicentre, randomised, open-label non-inferiority trial compared prophylactic SynFlow 3.0 micro-axial flow pump support with VA-ECMO during non-emergent high-risk PCI in patients with complex…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparison of alignment in patients with buccally displaced maxillary canines using T-loop mechanics and continuous arch mechanics: a randomized clinical trial.

This parallel, two-arm randomized clinical trial compared T-loop mechanics (TLM) with continuous arch mechanics (CAM) for aligning maxillary anterior teeth in 26 patients with unilateral or bilateral buccally displaced…

Clin Oral InvestigNov 10, 2026Read summary
Clinical ResearchPsychiatry

Changes in self-related cognitive processes and depressive symptom severity following a single, moderate dose of psilocybin in depressed patients.

This randomized, double-blind, placebo-controlled trial examined depressive symptoms, self-concept and neural markers of self-referential processing in 37 people with major depressive disorder.

Philos Trans R Soc Lond B Biol SciNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Acupuncture after surgery of soft tissue tumors of the extremities: postoperative pain and feasibility: a prospective trial.

This prospective, single-arm, single-centre pilot study assessed acupuncture feasibility and postoperative pain after extremity soft tissue tumor resection in 25 patients.

Langenbecks Arch SurgNov 10, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Whole-grain consumption and cardiometabolic risk: a meta-analysis of randomized trials.

This meta-analysis of randomized trials assessed how whole-grain intake affects cardiometabolic risk factors. It included 87 trials (101 publications) and estimated effects per 48 g/day increment in whole grains (dry…

Eur Heart JNov 10, 2026Read summary
Clinical ResearchGeneral SurgeryOpen access

Robotic pancreatic enucleation versus laparoscopic pancreatic enucleation: a meta-analysis.

This meta-analysis compared robotic with laparoscopic pancreatic enucleation for perioperative outcomes. It pooled five cohort studies involving 272 patients (128 robotic and 144 laparoscopic).

J Robot SurgNov 10, 2026Read summary
Clinical ResearchUrologyOpen access

Effect of pelvic floor reconstruction on postoperative urinary continence after robot-assisted radical prostatectomy: a meta-analysis.

This meta-analysis pooled controlled studies comparing pelvic floor reconstruction (PR) with no reconstruction during robot-assisted radical prostatectomy (RARP).

J Robot SurgNov 10, 2026Read summary
Clinical ResearchPreventive Medicine / Public HealthOpen access

Commonly experienced acute and cumulative 8-hour sleep loss differentially affect simulated driving during a night-time to early-morning commute: a randomized controlled crossover trial.

This randomized within-subject crossover trial compared simulated driving after normal sleep, four nights with 2 h less sleep per night, and one night without sleep in 20 healthy men.

SleepNov 10, 2026Read summary
Clinical ResearchCardiology

Sex differences in cardiovascular-kidney-metabolic syndrome: the FINE-HEART pooled analysis.

This prespecified pooled analysis combined participant-level data from three trials involving people with chronic kidney disease and type 2 diabetes or heart failure with mildly reduced or preserved ejection fraction.

Eur Heart JNov 10, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effectiveness of guided internet-delivered cognitive behavioral therapy for insomnia in autistic adults (i-Sleep Autism): a randomized controlled trial.

This randomized controlled trial evaluated a 5-week, guided internet-delivered cognitive behavioral therapy intervention adapted for autistic adults with insomnia.

SleepNov 10, 2026Read summary
Clinical ResearchHematologyOpen access

Physiological prehabilitation for patients undergoing cellular therapy in multiple myeloma and lymphoma: a systematic review.

This systematic review examined exercise-based physiological prehabilitation in adults with multiple myeloma or lymphoma before cellular or immune-based therapy.

Support Care CancerNov 10, 2026Read summary
Clinical ResearchPsychiatry

Testing the Impact of the #Chatsafe Intervention on Young People's Ability to Communicate Safely About Suicide on Social Media: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether #chatsafe social media content improved safe online communication about suicide among young people aged 16–25 years.

Suicide Life Threat BehavNov 10, 2026Read summary
Clinical ResearchGeneral Surgery

Efficacy of De-Epithelialized vs. Subepithelial Grafts in Periodontal Plastic Surgery for Gingival Recession: A Systematic Review and Meta-Analysis of Root Coverage Techniques.

This systematic review and meta-analysis compared de-epithelialized gingival grafts (DGG) with subepithelial connective tissue grafts (SCTG) for RT1 gingival recessions.

Clin Exp Dent ResNov 10, 2026Read summary
Clinical ResearchPulmonology

Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.

This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.

SleepNov 10, 2026Read summary
Case ReportNeurosurgery

Hyoid Bone Fracture in a Patient as a Rare Cause of Persistent Postoperative Dysphagia Following Anterior Cervical Discectomy and Fusion.

A 76-year-old woman developed severe, persistent dysphagia and progressive odynophagia after C3–5 anterior cervical discectomy and fusion.

Am J Case RepNov 10, 2026Read case
Clinical ResearchRheumatology

Comparative Efficacy of Different Biologic Agents on Radiographic Progression in Patients with Rheumatoid Arthritis: A Network Meta-Analysis.

This Bayesian random-effects network meta-analysis compared six biologic DMARD classes for radiographic progression in rheumatoid arthritis, using randomized controlled trials and change in modified Total Sharp Score…

Arch Immunol Ther Exp (Warsz)Nov 10, 2026Read summary
Case ReportObstetrics & GynecologyOpen access

Fetal myelomeningocele repair: Rome Fondazione Policlinico A. Gemelli IRCCS experience.

A fetus with distal lumbar myelomeningocele was assessed by fetal MRI, which showed a 23 × 11-mm defect, ventricular dilatation, and Chiari II malformation. Open fetal repair was performed at 25 weeks of gestation.

Childs Nerv SystNov 10, 2026Read case
Clinical ResearchCardiology

Left bundle branch area vs biventricular pacing for cardiac resynchronization therapy: the LEFT-BUNDLE-CRT trial.

The multicentre, randomized, non-inferiority LEFT-BUNDLE-CRT trial compared left-bundle branch area pacing (LBBAP) with biventricular pacing (BiVP) for cardiac resynchronization in patients with guideline-based…

Eur Heart JNov 10, 2026Read summary

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