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2000 articles

November 202624

Clinical ResearchOrthopedic Surgery

The Effect of Virtual Reality on Anxiety and Vital Signs in Patients Undergoing Total Knee Replacement Surgery: A Randomized Controlled Trial.

This randomized controlled trial evaluated whether intraoperative virtual reality affected anxiety and vital signs in 70 patients undergoing total knee replacement.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchPediatrics

Interventions to Support Parents Whose Babies Cry Excessively: Systematic Review.

This systematic review and meta-analysis assessed comparative studies of interventions supporting parents of babies aged ≤1 year with excessive crying.

PediatricsNov 1, 2026Read summary
Case ReportPediatrics

Green Vaginal Discharge in a Late-Preterm Neonate With Massive Ascites.

A late-preterm girl developed abdominal distension and respiratory distress shortly after birth, with anemia, coagulopathy, and massive ascites containing internal debris on ultrasonography.

NeoreviewsNov 1, 2026Read case
Case ReportPathology (Anatomic & Clinical)Open access

Non-Small Cell Lung Carcinoma With Bilayered Architecture and TP53 Alteration: A Diagnostic Pitfall and a Potential Distinct Entity.

A 75-year-old never-smoker had a 1.1-cm pulmonary nodule with an intact bilayered architecture, including a continuous basal cell layer.

Thorac CancerNov 1, 2026Read case
Clinical ResearchPsychiatryOpen access

Plasma Lipidomic Features of Adolescent Major Depressive Disorder and Lipid Changes After Fluoxetine Treatment.

This clinical trial study used UHPLC-MS/MS to compare plasma lipid profiles in 75 adolescents with major depressive disorder (MDD) and 75 matched healthy controls, and to assess changes after fluoxetine in 44…

CNS Neurosci TherNov 1, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Artificial Intelligence for Assessing the Relationship Between Mandibular Third Molars and the Inferior Alveolar Nerve on Panoramic Radiographs: A Systematic Review.

This systematic review assessed artificial intelligence (AI) models that use panoramic radiographs to evaluate the relationship between mandibular third molars and the inferior alveolar nerve, with cone-beam computed…

Med Oral Patol Oral Cir BucalNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

Clinical outcomes of Day-7 blastocysts: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared frozen Day-7 blastocyst transfers with Day-5 and Day-6 transfers.

Hum Reprod UpdateNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The Effect of Game-based Mobile Application in Learning Postpartum Hemorrhage Management for Midwifery Students.

This two-phase randomized controlled study developed and evaluated a game-based mobile application for postpartum hemorrhage (PPH) management education.

Comput Inform NursNov 1, 2026Read summary
Clinical ResearchObstetrics & GynecologyOpen access

Clinical outcomes and euploidy rates of embryos derived from zygotes with nonpronuclear (0PN) and monopronuclear (1PN) in IVF or ICSI cycles: a systematic review and meta-analysis.

This systematic review and meta-analysis compared euploidy and clinical outcomes for embryos derived from 0PN or 1PN zygotes with those from normally fertilized 2PN zygotes in IVF/ICSI cycles.

Hum Reprod UpdateNov 1, 2026Read summary
Clinical ResearchNeurologyOpen access

Inferior Frontal Gyrus Alterations in Freezing of Gait in Parkinson's Disease Without Evidence for Overall Hemispheric Lateralization: A Systematic Review and Activation Likelihood Estimation Meta-Analysis.

This systematic review and activation likelihood estimation meta-analysis examined neuroimaging differences between people with Parkinson’s disease who experience freezing of gait (freezers) and those who do not.

Eur J NeurosciNov 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Effects and Moderators of High-Intensity Interval Training (HIIT) on Physiological Adaptations Among Team-Sport Athletes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined HIIT added to regular sport-specific training in team-sport athletes. Across 46 studies involving 1204 athletes, HIIT was associated with improvements in several aerobic…

Scand J Med Sci SportsNov 1, 2026Read summary
Case ReportPediatrics

Excellent Long-Term Outcome in a Staged, Simultaneous Liver-Kidney Transplantation of a Highly Sensitized Pediatric Patient With B and T Cell Positive Crossmatch.

A highly sensitized small child with high-titer class I and II donor-specific antibodies underwent staged simultaneous liver-kidney transplantation from the same donor despite a positive cytotoxic crossmatch.

Pediatr TransplantNov 1, 2026Read case
Clinical ResearchRheumatologyOpen access

Sociodemographic factors, but not rurality, explain limited variance in fibromyalgia severity: a secondary analysis of 2 randomized clinical trials.

This secondary analysis combined baseline data from 685 participants in two randomized clinical trials to examine whether rural residence and sociodemographic characteristics were associated with fibromyalgia severity.

Pain MedNov 1, 2026Read summary
Clinical ResearchOphthalmology

In-the-Bag Stability of a New Hydrophilic Acrylic Toric Intraocular Lens.

This single-centre, prospective interventional clinical trial assessed in-the-bag stability of the RayOne EMV toric intraocular lens in 119 eyes of 79 patients with age-related cataract over 6 months.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Optimal Exercise Dose for Improving Multidimensional Health Outcomes in Colorectal Cancer Patients: A Systematic Review, Meta-Analysis and Meta-Regression.

This systematic review, meta-analysis and meta-regression examined exercise dose-response relationships in colorectal cancer patients.

Eur J Sport SciNov 1, 2026Read summary
Clinical ResearchGeneral Surgery

Long-Term Marginal Bone Stability of BOPT Restorations on Bone-Level vs. Tissue-Level Implants: An 8-Year Prospective Clinical Study.

This prospective randomized clinical study compared eight-year marginal bone loss in 122 posterior bone-level and tissue-level implants restored using the Biologically Oriented Preparation Technique (BOPT) in 71…

Med Oral Patol Oral Cir BucalNov 1, 2026Read summary
Clinical ResearchNeurology

Serum Insulin-Like Growth Factor-1 (IGF-1) in Parkinson's Disease: A Systematic Review and Meta-Analysis.

This systematic review and random-effects meta-analysis examined observational studies comparing serum IGF-1 in people with Parkinson’s disease (PD) and healthy controls, and studies of associations with PD symptoms.

Brain BehavNov 1, 2026Read summary
Clinical ResearchCardiologyOpen access

Elevated Lipoprotein(a) Predicts Recurrent Myocardial Infarction in Diabetic Patients Following Acute Coronary Syndromes.

This PRISMA-guided systematic review and meta-analysis assessed whether elevated lipoprotein(a) predicts recurrent events in patients with diabetes after acute coronary syndrome or percutaneous coronary intervention.

Clin CardiolNov 1, 2026Read summary
Case ReportOncology (Medical)Open access

Ascites Presenting as a Peritonitis-Like Manifestation and Liver Injury due to Trabectedin Monotherapy in a Patient With Myxoid Liposarcoma.

An 82-year-old woman with recurrent metastatic myxoid liposarcoma developed liver dysfunction and ascites while receiving trabectedin monotherapy, after 12 cycles.

Cancer Rep (Hoboken)Nov 1, 2026Read case
Clinical ResearchOncology (Medical)

A multicenter, prospective, phase 2 trial on proton re-irradiation for patients with previously treated head and neck cancer.

This multicenter, prospective phase 2 trial evaluated proton re-irradiation in patients with previously irradiated head and neck cancer.

CancerNov 1, 2026Read summary
Clinical ResearchObstetrics & Gynecology

The two-shot protocol. A randomized controlled trial of a novel two-injection ovarian stimulation strategy.

This phase III, single-centre randomised non-inferiority trial compared two sequential corifollitropin alfa (CFA) injections with conventional CFA followed by recombinant FSH in women undergoing elective fertility…

Hum ReprodNov 1, 2026Read summary
Clinical ResearchPediatrics

RSV Bivalent Prefusion F Protein Vaccine in Pregnancy and Protection Against RSV-Associated Illness in Infants: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed real-world effectiveness of maternal RSV bivalent prefusion F protein vaccination in preventing RSV-associated lower respiratory tract infection (LRTI) hospitalization…

JAMA PediatrNov 1, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Anatomy-specific Performance of CTA-based AI for Anterior Circulation Occlusion: Systematic Review and Meta-analysis.

This prospectively registered systematic review and diagnostic meta-analysis assessed CTA-based artificial intelligence for detecting anterior-circulation occlusions, using 31 reports involving 15 708 patients.

Radiol Artif IntellNov 1, 2026Read summary
Case ReportNeurology

Anti-Contactin-1 Nodopathy Presenting With Dysphagia and Nephrotic Syndrome: Remarkable Neurological and Renal Recovery Following Early B-Cell-Targeted Therapy.

A 77-year-old man with diabetes and pre-existing heavy proteinuria developed rapidly progressive distal numbness, weakness, sensory ataxia, mild dysphagia, and functional decline.

NeurologistNov 1, 2026Read case

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