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2000 articles
November 202624
A phase 2 study of tipifarnib in children and young adults with tumors harboring HRAS genomic alterations: NCI-COG Pediatric MATCH trial (APEC1621M).
This phase 2 NCI-COG Pediatric MATCH study evaluated intermittent oral tipifarnib in children and young adults with relapsed or refractory solid tumors carrying specified HRAS mutations.
Sirolimus-induced improvement of immune dysregulation associated hepatosplenomegaly in common variable immunodeficiency: a case-based review.
A 50-year-old woman with common variable immunodeficiency (CVID), treated with regular intravenous immunoglobulin replacement, developed progressive hepatosplenomegaly, cytopenias, abdominal enlargement, dyspnea…
Immediate gastrocnemius responses to intermittent cold compression at different pressure levels in soccer players.
This randomized crossover trial examined immediate responses to intermittent cold compression (ICC) after a soccer-specific fatigue protocol in seven male collegiate soccer players.
Targeting hormone conversion through dietary fiber improves polyendocrine metabolic ovarian syndrome.
This randomized controlled clinical trial examined a combination of inulin, resistant starch, and β-glucan in patients with polyendocrine metabolic ovarian syndrome (PMOS).
Calcific Deposition Within the Lateral Collateral Ligament of the Knee Presenting as Chronic Lateral Knee Pain: A Case Report.
A 50-year-old woman had progressive lateral knee pain for 5 years without preceding trauma. Examination showed focal tenderness over the lateral femoral epicondyle.
Human granulocytic anaplasmosis acquired in Switzerland: a case report.
A man in his early seventies taking methotrexate for ankylosing spondylitis and with tick exposure developed fever, headache and dizziness, followed by somnolence, dysarthria, ataxia and diplopia.
Efficacy of cognitive behavioral therapy for anxiety and depression symptoms in Parkinson's disease patients: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for anxiety and depressive symptoms in adults with Parkinson’s disease (PD), pooling 21 randomized controlled trials involving 892…
Cost-effectiveness of atosiban versus placebo for threatened preterm birth (APOSTEL 8 trial).
This economic evaluation alongside the multicentre randomised APOSTEL 8 trial compared atosiban with placebo for threatened preterm birth at 30+0 to 33+6 weeks’ gestation.
Pearls & Oy-sters: Trace Visualization of the Central Retinal Artery: A Favorable Sign for Late-Window Endovascular Therapy in Central Retinal Artery Occlusion.
A 69-year-old man presented with 18 hours of acute, severe blurred vision in the right eye. Fundus examination and optical coherence tomography showed central retinal artery occlusion with inner retinal edema.
A case report of ultra-rare SMARCD2 deficiency and review of the literature.
The report describes a patient with congenital neutropenia due to specific granule deficiency type 2, a syndromic autosomal recessive disorder associated with loss-of-function variants in SMARCD2.
Liposomal Bupivacaine versus Ropivacaine for Rhomboid Intercostal and Subserratus Plane Blocks in Video-Assisted Thoracoscopic Surgery: A Randomised Controlled Trial.
This single-centre randomised controlled trial compared liposomal bupivacaine (LB) with ropivacaine (RP) for ultrasound-guided rhomboid intercostal and subserratus plane blocks in patients undergoing video-assisted…
Reconstruction of the Burned Nose Using an Expanded Skin-Grafted Forehead Flap, Delayed Turnover Flaps, and Indocyanine Green Perfusion Assessment.
A 35-year-old man developed severe nasal deformity and airway compromise after a flame burn involving about 20% of total body surface area.
The effect of exercise program applied to patients with scleroderma on functional outcomes: A randomized controlled trial.
This randomized controlled trial assessed whether an exercise program improved hand and mouth function and quality of life in 46 patients with systemic sclerosis.
Coexistence of ARNT::ALK and TPM3::ALK doublegene fusion in an ALK-rearranged renal cell carcinoma with osseous metaplasia.
An adult patient had an ALK-rearranged renal cell carcinoma. The tumor showed varied growth patterns in a mucinous background, with a small peripheral focus of osseous metaplasia.
Enhancing Empathic Functioning in Married Individuals Experiencing Marital Conflict Through Mentalization-Based Therapy in Iran.
This randomized controlled study examined whether Mentalization-Based Therapy (MBT) changed self-reported empathy among 30 married individuals experiencing marital conflict in Iran.
Classification Systems and Clinical Outcomes of Axillary Burn Contracture: A Systematic Review and Meta Analysis.
This systematic review and meta-analysis examined classification systems and surgical outcomes for axillary burn contracture.
Maternal and Fetal Outcomes in Pregnant Women with Burn Injuries: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled maternal and fetal mortality in pregnant women with burn injuries, using observational studies and case series.
Adjunctive Imaging to Confirm Ultrasound-Guided Paravertebral Catheter Tip Position in Children: Case Reports.
The report describes children receiving ultrasound-guided paravertebral catheters for perioperative analgesia during thoracic procedures.
Genetic Counseling and Shared Decision-Making for a Male Carrier of a Balanced Reciprocal Translocation Facing Financial Barriers to Preimplantation Genetic Testing for Structural Rearrangements: A Case Study.
A man in his early thirties with severe oligozoospermia was found to carry a balanced reciprocal translocation. Genetic counseling covered reproductive risks, PGT-SR and prenatal testing options, expected outcomes, and…
Socioeconomic Inequalities in Dietary and Physical Activity Behaviours Among Adolescents: A Systematic Review.
This systematic review synthesized observational evidence on socioeconomic position and dietary or physical activity behaviours among adolescents. Of 22,897 records identified, 38 studies met the eligibility criteria.
Topical MSC-Derived Extracellular Vesicles Accelerate Healing of Second-Degree Burns: A Case Report.
A 48-year-old man with deep second-degree burns received a single topical dose of allogeneic bone marrow mesenchymal stem cell-derived extracellular vesicles within 48 hours of injury in an open-label phase 1/2a study.
Health-centric information and moisture management for the adoption of postharvest practices to reduce mycotoxin risk: evidence from black pepper farmers in Sri Lanka.
This randomized controlled trial examined whether health-centric information and moisture-management interventions, alongside general mycotoxin information and government training, changed postharvest practices among…
Successful ABO-incompatible renal transplantation of blood group A1 donor into A2 recipient with anti-A1 isoagglutinins: case report and review of literature.
A 73-year-old woman with end-stage kidney disease due to AL amyloidosis was evaluated for kidney transplantation. An ABO typing discrepancy led to serologic testing and genotyping, which confirmed an A2 recipient with…
Surgical Procedure to Optimize the Esthetic and Osseous Outcomes for Young Adults with Large Periradicular Defects: Two Case Reports.
The report describes two young adults with teeth affected by internal root resorption or persistent large periapical lesions after nonsurgical endodontic treatment.
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