Written exposure therapy as treatment for comorbid PTSD and SUD: a systematic review and meta-analysis.

Curr Psychiatry RepNov 7, 2026 (epub)
Clinical ResearchPsychiatryOpen access

Tooba Fatima, Sarah Catchlove, Satish Melwani et al.

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In 30 seconds

This systematic review and meta-analysis assessed Written Exposure Therapy (WET) as a component of integrated treatment for people with comorbid post-traumatic stress disorder (PTSD) and substance use disorder (SUD). Twelve studies were included; a random-effects meta-analysis of six studies found a large pre-to-post reduction in PTSD severity (Hedges' g = 1.18, 95% CI [0.68, 1.72], p < 0.001). Retention was 69.03%, and most participants and providers considered WET feasible and acceptable. The findings support WET as a potentially useful integrated-treatment component, while evidence about SUD outcomes remains limited.

Key findings

  • Across six studies, PTSD severity decreased from before to after treatment (Hedges' g = 1.18, 95% CI [0.68, 1.72], p < 0.001).
  • Retention was 69.03%, higher than typically reported for integrated prolonged exposure treatments for PTSD-SUD.
  • Most participants and providers considered WET feasible and acceptable, although some participants found concurrent treatment burdensome.

Why it matters

PTSD and SUD can be treated concurrently, but integrated approaches may impose treatment burden. These findings suggest that WET, described as brief and low-burden to integrate, may be a feasible option within such care. The evidence is preliminary, however, and does not establish comparative effectiveness or clarify effects on SUD.

What to keep in mind

The review reports small samples, lack of comparator groups, and limited information about treatment components and changes in SUD.

Source

Published in Curr Psychiatry Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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