Is plant-based protein supplementation as effective as whey protein? A systematic review and meta-analysis in untrained adults undergoing resistance training.

J Int Soc Sports NutrOct 29, 2026 (epub)

Irineu Otavio Marchiori Callegari, Giovana Molina Silva, Alexandre Gabarra Oliveira

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis compared plant-based with whey protein supplementation for body composition in untrained adults aged 18–59 years undertaking resistance training. Five studies met the criteria for qualitative synthesis and meta-analysis, with outcomes assessed using dual-energy X-ray absorptiometry. Both supplement types, when combined with training, were associated with improvements in lean body mass and body fat mass. The analysis found no statistically significant between-group differences, but the limited evidence does not establish that the protein sources are physiologically equivalent.

Key findings

  • Five studies were included in the qualitative synthesis and meta-analysis.
  • Plant-based and whey protein supplementation alongside resistance training were both associated with improvements in lean body mass and body fat mass.
  • No statistically significant between-group differences in body composition outcomes were observed.
  • Evidence for chia-based protein was limited to one study, which did not demonstrate significant lean body mass changes.

Why it matters

The findings suggest that soy- or pea-based supplements may be options for adults beginning resistance training who prefer alternatives to whey. However, absence of a statistically significant difference is not proof of equivalence. The small evidence base and wide confidence intervals mean that comparative effects remain uncertain, so conclusions about protein-source superiority should be cautious.

What to keep in mind

Only five studies were included, and the source notes wide confidence intervals and limited evidence, particularly for chia-based protein. The analysis therefore cannot establish physiological equivalence between plant-based and whey protein.

Source

Published in J Int Soc Sports Nutr. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

ShareTelegramLinkedIn

AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

More in Preventive Medicine / Public Health

Want this personalized?

Stop searching the literature. Choose what you follow and xxcode will build your personalized medical digest.

  • Your specialties
  • Your filters and thresholds
  • Clinical Research + Case Reports, tuned separately
  • Automatic weekly delivery
  • Audio and text

Prefer listening? Personalized audio digests are available with Pro.

Stay updated for free

Get the 3 most interesting publications in one specialty each week.

Weekly email. Unsubscribe anytime.