Effect of exercise on bone health in middle aged and older adults: hierarchical network meta-analysis of randomised trials.
Changbo Lu, Liwen Li, Lei Zhang et al.
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In 30 seconds
This hierarchical network meta-analysis evaluated the impact of various exercise types on bone mineral density (BMD) and fracture risk in adults aged 40 and older. The analysis included 124 trials with 18,429 participants. Results indicated that brisk walking or jogging and combined aerobic-resistance exercises likely improve lumbar spine BMD by 0.013 g/cm² compared to controls, while mixed aerobic and mind-body exercises may reduce fracture risk.
Key findings
- Brisk walking or jogging likely improves lumbar spine BMD by 0.013 g/cm² compared to controls.
- Mind-body exercise may enhance femoral neck BMD by 0.007 g/cm² with moderate certainty.
- Mixed aerobic exercise may reduce fracture risk with an odds ratio of 0.29.
- Clinically meaningful benefits may be achieved at around 600 METs-min/week.
Why it matters
Understanding the specific types and doses of exercise that benefit bone health is crucial for developing effective prevention strategies against osteoporosis and fractures in aging populations. This knowledge can guide clinicians in recommending tailored exercise regimens.