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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchEndocrinology

Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

Nutr RevNov 12, 2026

This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…

Why it matters

The findings distinguish a reliable increase in vitamin D status from broader functional or body-composition benefits. For clinicians interpreting supplementation alongside exercise, the pooled evidence does not show…

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Also worth knowing

Clinical ResearchOrthopedic Surgery

Interventions for adhesive capsulitis: systematic review and network meta-analysis of randomised controlled trials.

This systematic review and network meta-analysis compared treatments for adhesive capsulitis in adults, including 189 randomised controlled trials with 12 988 participants and 59 interventions.

BMJNov 4, 2026Read summary
Clinical ResearchOrthopedic Surgery

Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.

This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…

CMAJNov 9, 2026Read summary
Clinical ResearchGastroenterology

European Guidelines on Multidisciplinary Management of Obstructed Defecation Syndrome-ESCP, UEG, ESGAR, EAGEN, ESGENA, ESNM and ESPCG.

These European multidisciplinary practice guidelines address diagnosis and management of obstructed defecation syndrome (ODS).

United European Gastroenterol JNov 1, 2026Read summary
Clinical ResearchPediatrics

Efficacy of Manual Physiotherapy Techniques for Improving Cervical Range of Motion in Infants With Congenital Muscular Torticollis: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed therapist-directed manual physiotherapy techniques for cervical range of motion (ROM) in infants with congenital muscular torticollis.

Physiother Res IntNov 7, 2026Read summary
Clinical ResearchPediatrics

Chest physiotherapy for pneumonia in children.

This Cochrane systematic review and meta-analysis assessed randomised trials of chest physiotherapy versus usual care in hospitalised children with pneumonia.

Cochrane Database Syst RevNov 6, 2026Read summary
Clinical ResearchOrthopedic Surgery

Supervised physiotherapeutic scoliosis-specific exercises provide limited additional benefit at 24 months in braced adolescents with idiopathic scoliosis: a randomized trial.

This randomized trial compared supervised Schroth-based physiotherapeutic scoliosis-specific exercises (PSSE) with self-directed general exercise in adolescents with idiopathic scoliosis receiving brace treatment.

Bone Joint JNov 1, 2026Read summary
Clinical ResearchGeriatrics

Effect of Exercise Interventions on Sarcopenia-Related Outcomes in Older Adults With Type 2 Diabetes: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed structured exercise versus nonexercise control in adults with type 2 diabetes whose mean age was at least 65 years.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchGeriatrics

Exercise and Nutritional Interventions for Muscle Strength, Physical Performance, and Body Composition Among Older Adults With Sarcopenia or Pre-Sarcopenia: A Network Meta-Analysis.

This network meta-analysis compared exercise, nutritional, and combined interventions with control strategies in older adults with sarcopenia or pre-sarcopenia.

Geriatr Gerontol IntNov 1, 2026Read summary
Clinical ResearchGeriatricsOpen access

Prevalence of fall risk and fear of falling among older adults in the Middle East and North Africa: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated fall risk and fear of falling among adults aged 60 years or older in the Middle East and North Africa (MENA).

J Glob HealthOct 30, 2026Read summary
Clinical ResearchNeurology

Cutaneous Silent Period-Based Comparison of Dorsal Root Ganglion Pulsed Radiofrequency and Transforaminal Epidural Steroid Injection in Lumbar Radicular Pain: A Randomized Controlled Trial.

This prospective, single-blind randomized controlled trial compared dorsal root ganglion pulsed radiofrequency (DRG-PRF) with transforaminal epidural steroid injection (TFESI) in 36 patients with chronic unilateral…

Clin J PainNov 11, 2026Read summary
Clinical ResearchPsychiatry

The Role of Stress-Related Biomarkers, Immune-Inflammatory Pathways, and Genetic Polymorphisms in Cognitive-Behavioral Therapies for Chronic Low Back Pain and Depression: Results From a Randomized Controlled Trial (The IMPACT Study).

This randomized controlled trial examined whether Acceptance and Commitment Therapy (ACT) or Behavioral Activation Therapy for Depression (BATD), each added to usual care, affected biomarkers or clinical outcomes in 114…

Clin J PainNov 11, 2026Read summary

Showing 12 of 49 publications that cleared our clinical screen in the last 14 days.

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