Cone-Beam Computed Tomography Imaging of Primary Non-Hodgkin Lymphoma of the Jaws: A 6-Case Series.
Emmanouil Chatzipetros, Konstantina-Eleni Alexiou, Kostas Tsiklakis et al.
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Case in brief
This case series examined six patients with histopathologically confirmed primary non-Hodgkin lymphoma (NHL) of the jaws, who initially presented with symptoms such as paresthesia, tooth mobility, and facial swelling. Cone-beam computed tomography (CBCT) revealed osteolytic lesions with ill-defined borders and cortical destruction, often affecting the mandible more than the maxilla. The diagnosis was confirmed through biopsy, highlighting the need for awareness of these imaging characteristics.
What made this case unusual
The presence of floating teeth and a spiked-tooth appearance in several cases indicated aggressive disease, which is atypical for common odontogenic conditions.
Diagnostic / clinical pearl
Clinicians should be aware that primary NHL of the jaws can mimic odontogenic or inflammatory conditions, but specific CBCT findings like ill-defined osteolysis and cortical involvement should raise suspicion for malignancy.
Why it matters
Recognizing the characteristic imaging features of primary NHL can facilitate earlier diagnosis and appropriate management, reducing the risk of delayed treatment.