A Novel Multiple Sensory Nerve Block Combination Using Ultrasound Guidance in Knee Arthroplasty: A Randomized Clinical Trial.
A A PractSep 8, 2026 (epub)
Fredrik Fellert, Fredrik Sjövall, Gunnar Flivik et al.
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In 30 seconds
This randomized clinical trial evaluated the efficacy of an eight-nerve block combination for pain relief after total knee arthroplasty (TKA) compared to local infiltration analgesia (LIA). In a cohort of 217 patients, no significant differences in postoperative pain intensity were found between the two groups. However, the nerve block group showed reduced 48-hour opioid consumption and a shorter hospital stay.
Key findings
- No significant differences in pain scores were observed between the nerve block and LIA groups at any time point.
- The nerve block group had a median 48-hour opioid consumption of 70 mg compared to 96 mg in the LIA group (P = .008).
- Patients in the nerve block group had a median hospital stay of 1 day versus 2 days in the LIA group (P < .001).
Why it matters
Effective pain management is crucial in postoperative care, particularly after TKA. Understanding the comparative effectiveness of analgesic techniques can help optimize recovery and resource utilization in surgical settings.