The utility of 18F-fluorodeoxyglucose PET/computed tomography in relapsing polychondritis: a systematic review and meta-analysis.

Nucl Med CommunSep 8, 2026 (epub)
Clinical ResearchRheumatologyRadiology (Diagnostic)

Pareena Malik, Dhananjaya Saraswat, Piyush Aggarwal et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis evaluated the utility of 18F-fluorodeoxyglucose PET/CT in relapsing polychondritis, analyzing data from three studies involving 97 patients. The findings revealed a high pooled PET-positivity rate of 94% (95% CI: 73-99%), indicating its potential role in identifying asymptomatic cartilage involvement and monitoring treatment.

Key findings

  • The pooled PET-positivity rate was 94% (95% CI: 73-99%).
  • 18F-FDG PET identified asymptomatic cartilage involvement in over 25% of patients.
  • The pooled baseline SUVmax was 4.0 (95% CI: 3.5-4.6).
  • PET parameters correlated well with inflammatory markers.

Why it matters

Understanding the role of 18F-FDG PET/CT in relapsing polychondritis can enhance diagnostic accuracy and treatment monitoring, particularly for asymptomatic cartilage involvement, which may influence patient management strategies.

Source

PubMed · PMID 42712171

Published in Nucl Med Commun. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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