Intrathecal bupivacaine monotherapy in patients with chronic refractory localized pain: a case series.

Reg Anesth Pain MedSep 8, 2026 (epub)

Salim Michel Hayek, Cham Alsalak

✦ AI-curated · Sources linked

Case in brief

This case series examined five patients with chronic localized pain who received intrathecal bupivacaine monotherapy after device implantation. All patients had a history of pain management, with some previously on opioid therapy. Following the transition to bupivacaine monotherapy, each patient reported at least 50% pain relief and successfully discontinued systemic opioids.

Diagnostic / clinical pearl

Intrathecal bupivacaine monotherapy can provide significant pain relief in patients with chronic localized pain, allowing for the discontinuation of systemic opioids.

Why it matters

This case series highlights the potential of bupivacaine monotherapy in managing chronic pain, suggesting a need for further research to confirm its safety and efficacy.

Source

Published in Reg Anesth Pain Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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AI-generated summaries may contain errors or omissions. Verify clinically important information with the original publication.

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