Rapidly progressive glomerulonephritis in rheumatoid arthritis: an early presentation of ANCA-associated vasculitis.

BMJ Case RepSep 2, 2026 (epub)
Case ReportNephrologyRheumatology

Jegadis Sreeneyasan, Roberta Dewar, Seema Rana et al.

✦ AI-curated · Sources linked

Case in brief

A 68-year-old man with newly diagnosed seropositive rheumatoid arthritis presented with rapidly progressive glomerulonephritis just six months after his arthritis diagnosis. His renal function deteriorated acutely, leading to the detection of positive myeloperoxidase (MPO)-ANCA serology and a renal biopsy that confirmed pauci-immune necrotising crescentic glomerulonephritis. The condition was managed effectively following diagnosis.

Diagnostic / clinical pearl

Clinicians should consider ANCA-associated vasculitis in patients with rheumatoid arthritis who experience acute kidney injury, even if the autoimmune condition is newly diagnosed.

Source

PubMed · PMID 42697568

Published in BMJ Case Rep. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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