A multicenter randomized controlled effectiveness trial of transdiagnostic treatment for adolescents with subthreshold anxiety and depressive symptoms.
Eduardo Fonseca-Pedrero, Alfonso Pérez-Esteban, Adriana Díez-Gómez et al.
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In 30 seconds
This multicenter randomized controlled trial evaluated the effectiveness of the Unified Protocol for Adolescents (UP-A) compared to progressive relaxation in 676 adolescents with subthreshold anxiety and depressive symptoms. Both interventions significantly reduced symptoms over time, with the UP-A group showing marginally lower depressive symptoms and neuroticism at 12 months. No significant between-group differences were found.
Key findings
- Both UP-A and control groups showed significant reductions in depressive and anxiety symptoms over time.
- At 12 months, the UP-A group had marginally lower depressive symptoms and neuroticism.
- Significant treatment effects favoring UP-A were observed for hyperactivity, conduct problems, and total mental health difficulties.
- Adherence was high, with approximately 78% of participants attending more than 70% of sessions.
Why it matters
The study highlights the potential of structured, group-based interventions to effectively reduce emotional symptoms in adolescents, which is crucial for addressing mental health issues early and preventing the development of more severe disorders.