Prognostic significance of stress hyperglycemia ratio in patients undergoing percutaneous coronary intervention: a dose-response meta-analysis.
BMJ Open Diabetes Res CareAug 31, 2026 (epub)
Jinyu He, Qianxiang Wang, Junhua He et al.
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In 30 seconds
This meta-analysis evaluated the prognostic significance of the stress hyperglycemia ratio (SHR) in 41,096 patients undergoing percutaneous coronary intervention (PCI). It found that elevated SHR is associated with increased risks of adverse outcomes, including major adverse cardiac and cerebrovascular events (MACCE). The analysis indicated a linear dose-response relationship between SHR and MACCE.
Key findings
- Elevated SHR was linked to increased all-cause mortality and MACCE.
- The dose-response analysis suggested a linear relationship between SHR and MACCE.
- No association was found between SHR and repeat revascularization.
Why it matters
Understanding the prognostic value of SHR can help clinicians better assess risk in PCI patients, potentially guiding management strategies to improve outcomes.
What to keep in mind
Most studies were observational, and definitions of SHR varied, which may introduce residual confounding.