COVID-19-Induced Narcolepsy Type I With Cataplexy: A Short Report.

J Sleep ResMay 29, 2026 (epub)
Case ReportNeurology

Torsten Vinding Merinder, Martin Langeskov-Christensen, Filip Kirov

✦ AI-curated · Sources linked

Case in brief

A 42-year-old healthy female developed excessive daytime sleepiness, cataplexy, and hallucinations three months post-SARS-CoV-2 infection. Polysomnography revealed disturbed sleep patterns, while the multiple sleep latency test indicated a mean latency of 1 minute with REM sleep onset. Low cerebrospinal fluid hypocretin levels confirmed narcolepsy type I. Treatment with methylphenidate and venlafaxine significantly improved her symptoms and daily functioning.

What made this case unusual

This case highlights the onset of narcolepsy type I with cataplexy following COVID-19, contributing to the limited literature on this association.

Diagnostic / clinical pearl

Clinicians should consider narcolepsy type I in patients experiencing persistent fatigue and hypersomnolence after COVID-19, as early diagnosis can lead to effective management.

Why it matters

Understanding the potential neurological sequelae of COVID-19, including narcolepsy, is crucial for timely intervention and improved patient outcomes.

Source

PubMed · PMID 42215284

Published in J Sleep Res. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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