Brief Report: Sustainability of the Effects of Linkage Case Management on Posthospitalization HIV Outcomes: The Daraja Randomized Clinical Trial.
J Acquir Immune Defic SyndrSep 1, 2026
Megan Willkens, Benson Issarow, Godfrey A Kisigo et al.
✦ AI-curated · Sources linked
In 30 seconds
This randomized controlled trial evaluated the sustainability of linkage case management on posthospitalization outcomes in people with HIV over 24 months. Participants who received the intervention showed significantly higher rates of continuity in HIV care (78.6% vs 66.3%), persistent ART adherence (74.1% vs 61.0%), and viral load suppression (70.1% vs 57.6%) compared to standard care.
Key findings
- Continuity in HIV care was 78.6% in the intervention group versus 66.3% in standard care (P = 0.008).
- Persistent ART adherence was 74.1% in the intervention group compared to 61.0% in standard care (P = 0.006).
- Viral load suppression was achieved in 70.1% of the intervention group versus 57.6% in standard care (P = 0.01).
- Over 10% of control participants remained untreated after 2 years.
Why it matters
Sustained engagement in HIV care and adherence to ART are critical for improving health outcomes and reducing transmission. This study highlights the effectiveness of linkage case management in maintaining these outcomes post-discharge.