A systematic review of acute and long-term outcomes in patients with non-transvenous implantable cardioverter-defibrillators.
Steven Zweibel, David Lanctin, Reece Holbrook et al.
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In 30 seconds
This systematic review evaluated the outcomes of non-transvenous implantable cardioverter-defibrillators (ICDs) in adult patients with guideline-based indications. Analyzing 25 studies with 4,633 patients, the review found procedural success rates ranging from 81% to 100% and clinical defibrillation success consistently high at 95%-100%. The findings support the safety and effectiveness of non-transvenous ICDs.
Key findings
- Procedural success rates ranged from 81% to 100%, with most studies reporting rates ≥94%.
- Long-term complication rates were 0%-8% at 0.5-1.5 years and 1%-14% beyond 1.5 years.
- All-cause mortality increased from 1%-5% within 6 months to 16%-26% at 4-8 years.
- Inappropriate shock incidence ranged from 7%-13% at 1 year and 2%-18% at later timepoints.
Why it matters
Understanding the safety and effectiveness of non-transvenous ICDs is crucial for clinicians managing patients with life-threatening arrhythmias. This review provides evidence supporting their use, potentially influencing treatment decisions and patient outcomes.