High-intensity interval training combined with moderate-intensity continuous training in post-PCI acute myocardial infarction patients: A randomized controlled trial.
Weilin Wang, Yingchun Gu, Dongwei Wang et al.
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In 30 seconds
This randomized controlled trial evaluated the efficacy and safety of combined high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) in 204 post-PCI acute myocardial infarction patients. The study found that combined training significantly improved peak oxygen consumption (VO2 peak) by 5.6 ± 2.3 mL/kg/min compared to MICT alone (2.7 ± 1.9 mL/kg/min, P < .001) and HIIT alone (4.2 ± 1.8 mL/kg/min, P = .003).
Key findings
- Combined training improved VO2 peak by 5.6 ± 2.3 mL/kg/min compared to MICT alone (2.7 ± 1.9 mL/kg/min, P < .001).
- 76.7% of patients in the combined training group achieved a clinically meaningful improvement in VO2 peak (≥3 mL/kg/min).
- Left ventricular ejection fraction (LVEF) increased by 8.6 ± 3.2% in the combined training group.
- The incidence of major adverse cardiovascular events (MACE) was low at 2.9%, with no significant inter-group differences (P = .85).
Why it matters
This study highlights the potential of combined HIIT and MICT training to enhance cardiopulmonary function and cardiac remodeling in post-PCI AMI patients, suggesting a more effective rehabilitation strategy that may improve patient outcomes.