Identification of clinical risk factors for arrhythmia recurrence in patients with atrial fibrillation undergoing catheter ablation: A systematic review and meta-analysis.

Heart RhythmApr 29, 2026 (epub)
Clinical ResearchCardiology

Kimmy W P Chan, Doris S F Yu, Joshua W K Ho et al.

✦ AI-curated · Sources linked

In 30 seconds

This systematic review and meta-analysis examined clinical risk factors for arrhythmia recurrence in patients with atrial fibrillation (AF) post-catheter ablation, analyzing data from 152 studies with 49,919 patients. Key findings revealed that smoking (aHR 2.15) and periodontitis (aHR 2.04) were among the strongest predictors of recurrence, highlighting the importance of preablation risk assessment.

Key findings

  • Smoking was associated with a 2.15-fold increased risk of arrhythmia recurrence (aHR 2.15 [1.49-3.10]).
  • Periodontitis showed a 2.04-fold increased risk of recurrence (aHR 2.04 [1.48-2.83]).
  • Untreated sleep apnea conferred a heightened risk with an aHR of 2.41 (1.51-3.86).
  • Depression was linked to a 2.86-fold increased risk of recurrence (aOR 2.86 [1.51-5.41]).

Why it matters

Understanding the clinical risk factors for arrhythmia recurrence after AF ablation can guide clinicians in personalizing patient assessments and optimizing preprocedural interventions, potentially improving outcomes.

Source

PubMed · PMID 42066879

Published in Heart Rhythm. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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