Childhood cognitive control as a predictor of long-term clinical and functional outcomes in Tourette syndrome.

J Child Psychol PsychiatryApr 21, 2026 (epub)
Clinical ResearchPsychiatryOpen access

Kathryn E Barber, Emily J Ricketts, Douglas W Woods et al.

✦ AI-curated · Sources linked

In 30 seconds

This randomized controlled trial examined the role of childhood cognitive control in predicting long-term outcomes in 80 individuals with Tourette syndrome (TS). The study found that better childhood cognitive control, including inhibition and processing speed, was associated with lower tic severity and higher quality of life in early adulthood, with significant results maintained after adjusting for comorbidities.

Key findings

  • Greater inhibition and processing speed in childhood predicted lower tic severity and impairment in early adulthood.
  • Higher odds of tic remission were associated with better childhood cognitive control.
  • Improved working memory and response flexibility correlated with higher educational attainment and income.

Why it matters

Understanding the predictors of long-term outcomes in Tourette syndrome can inform treatment strategies and interventions. Enhancing cognitive control in childhood may improve clinical and functional trajectories for individuals with TS.

Source

PubMed · PMID 42012022Free full text on PubMed Central

Published in J Child Psychol Psychiatry. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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