Right Temporal Variant Frontotemporal Dementia Presenting With Prosopagnosia: Insights From 18 F-FDG PET and MRI.

Clin Nucl MedMar 19, 2026 (epub)

Muhammet Halil Baltacioglu, Pelin Sahin Oguz, Mehmet Sabri Erdol

✦ AI-curated · Sources linked

Case in brief

A 62-year-old man developed progressive difficulty recognizing people, accompanied by memory impairment. T2-weighted MRI showed atrophy of the right anterior temporal region. 18F-FDG PET demonstrated marked hypometabolism in the right temporal lobe, with additional involvement of the right frontal and anterior cingulate cortices; quantitative SPM Z-score analysis supported these findings. The combined structural and metabolic pattern was consistent with right temporal variant frontotemporal dementia, which affects networks involved in person recognition.

What made this case unusual

The case provides a multimodal depiction of right temporal variant frontotemporal dementia, including detailed 18F-FDG PET findings alongside MRI; the authors note that such PET characterization remains scarce.

Diagnostic / clinical pearl

Progressive prosopagnosia with right anterior temporal atrophy and corresponding right temporal hypometabolism can point to right temporal variant frontotemporal dementia.

Source

PubMed · PMID 41911262

Published in Clin Nucl Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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