Glucocorticoid Therapy and Miglitol Ameliorate Reactive Hypoglycemia Secondary to Late Dumping Syndrome.

Intern MedFeb 24, 2026 (epub)
Case ReportEndocrinologyGastroenterology

Manabu Saito, Hiroshi Uchino, Arisa Yoshida et al.

✦ AI-curated · Sources linked

Case in brief

A 73-year-old man developed symptomatic reactive hypoglycemia attributed to late dumping syndrome after esophagectomy with gastric tube reconstruction. Frequent dietary management and voglibose, a non-absorbable α-glucosidase inhibitor, did not control the hypoglycemia. After treatment was changed to low-dose prednisolone and miglitol, an absorbable α-glucosidase inhibitor, the hypoglycemia improved and his symptoms resolved.

What made this case unusual

Hypoglycemia persisted despite dietary management and voglibose, but improved after switching to low-dose prednisolone and miglitol.

Diagnostic / clinical pearl

In this reported case, late dumping syndrome caused reactive hypoglycemia after esophagectomy; persistent symptoms despite dietary measures and voglibose improved with low-dose prednisolone and miglitol.

Source

PubMed · PMID 41730617

Published in Intern Med. This summary was written by xxcode from the publication's abstract and metadata. It is not peer reviewed and is not a substitute for the original article. For clinical decisions, review the original publication.

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