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1357 articles
November 202624
2025 National Guidelines on the Mediterranean Diet: Executive Summary of a Joint Report by Italian Scientific Societies and the National Institute of Health Task Force on Clinical Practice Guidelines.
This systematic review and practice guideline, developed by a multidisciplinary panel using NUTRIGRADE, assessed Mediterranean diet evidence across nine health domains and one economic domain.
Exploring the Association Between Cannabis Use and Male Reproductive Parameters: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined associations between cannabis use and male reproductive parameters. It included 18 studies reporting sperm outcomes (5,766 patients; 6,231 samples) and hormonal outcomes…
The Role of Diet and Physical Activity in Gut Microbiota Modulation in Type 2 Diabetes Management: A Systematic Review of Clinical Trials.
This systematic review assessed clinical trials of dietary and physical activity interventions and gut microbiota in adults with type 2 diabetes or prediabetes.
Efficacy or Effectiveness of Zinc-Biofortified Staples in Improving Biomarkers of Zinc Status: A Systematic Review.
This systematic review assessed randomized controlled trials of zinc-biofortified staple crops and biomarkers of zinc status. Seven studies met the eligibility criteria.
Effects of Polyphenols on Gut Health and Inflammation in Overweight and Obese Populations: A Systematic Review and Meta-analysis of Dose, Duration, and Food Matrix.
This systematic review and meta-analysis assessed polyphenol interventions and gut microbiota and inflammatory biomarkers in people with overweight or obesity, drawing on 32 randomized controlled trials.
Association Between Vitamin D Status and Nocturnal Lower Urinary Tract Symptoms: A Pooled Analysis.
This systematic review and meta-analysis assessed associations between vitamin D status or intake and nocturnal lower urinary tract symptoms (nLUTS), drawing on 17 studies: 5 randomised trials, 2 cohort studies, 4…
Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.
This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…
Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.
This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.
Effects of Vitamin D Supplementation in Combination With Exercise Training on Body Composition and Muscular Strength in Adults: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.
This systematic review and dose-response meta-analysis of randomized controlled trials assessed whether vitamin D supplementation added to exercise improves body composition or muscular strength compared with exercise…
Current Evidence of Digital and Hand Replantation Following Cold Ischemia or Cryopreservation: A Systematic Review.
This systematic review examined published outcomes after digit or hand replantation when preservation was at or below 10°C or exceeded 6 hours.
The unseen risk: a systematic review of the incidence, management, and outcomes of the trigeminocardiac reflex in skull-base surgery.
This PRISMA-guided systematic review synthesized reports of intraoperative trigeminocardiac reflex (TCR) during skull-base and adjacent neurosurgical procedures.
Cardiovascular disease and stroke prevention educational-behavioural programmes for culturally and/or linguistically diverse communities: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed cardiovascular disease (CVD) and stroke prevention educational-behavioural programmes for people from culturally and/or linguistically diverse (CALD) backgrounds.
Predictors and prognostic impact of spontaneous portal vein thrombosis recanalization in cirrhosis: An individual patient data meta-analysis.
This individual patient data meta-analysis pooled cohort studies of patients with cirrhosis and portal vein thrombosis (PVT) who were not receiving anticoagulation.
Socio-economic status, cardiovascular risk factors, and coronary atherosclerosis: a SCOT-HEART trial analysis.
This post-hoc analysis of a multicentre randomised trial examined socioeconomic status (SES) in relation to coronary CT angiography (CCTA) plaque features, management, and cardiovascular outcomes.
The Role of Stress-Related Biomarkers, Immune-Inflammatory Pathways, and Genetic Polymorphisms in Cognitive-Behavioral Therapies for Chronic Low Back Pain and Depression: Results From a Randomized Controlled Trial (The IMPACT Study).
This randomized controlled trial examined whether Acceptance and Commitment Therapy (ACT) or Behavioral Activation Therapy for Depression (BATD), each added to usual care, affected biomarkers or clinical outcomes in 114…
Home-Based, Digitally Assisted Dyadic Tai Chi Intervention for Patients With Chronic Heart Failure and Their Caregivers: Development of an Intervention and Pilot Randomized Controlled Trial.
This sequential, multiphase study developed a home-based, digitally assisted tai chi programme for people with chronic heart failure (CHF) and their caregivers, then evaluated it in a single-centre, assessor-blinded…
Sperm DNA Fragmentation Index, Semen Quality, and Assisted Reproductive Technology Outcomes: A Systematic Review and Meta-analysis of Observational Studies.
This systematic review and meta-analysis of 87 observational studies assessed associations between sperm DNA fragmentation index (DFI), semen parameters, and assisted reproductive technology (ART) outcomes.
Differential effects of pea protein isolate, pea protein concentrate, and whey protein isolate supplementation on gut microbiota and metabolic markers in healthy adults: a 3-arm parallel randomised intervention.
This double-blind, three-arm randomised dietary intervention compared four weeks of pea protein concentrate (PPC), pea protein isolate (PPI), or whey protein isolate (WPI) supplementation in healthy adults.
Imaging-Based AI for Predicting Pathological Complete Response in Esophageal Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.
A Superior Spermatic Cord Denervation Technique?: A Meta-Analysis.
This systematic review and meta-analysis compared standard, targeted complex, and robotic-assisted spermatic cord denervation for men with chronic orchialgia.
The Safety, Pharmacokinetics, and Antiviral Activity of ABI-4334, A Novel Next-Generation Hepatitis B Capsid Assembly Modulator.
Two randomized Phase 1 studies assessed ABI-4334, a hepatitis B capsid assembly modulator, in healthy volunteers and participants with chronic hepatitis B (cHBV).
Effect of dietary counselling on educational disparities in cardiometabolic health from childhood to adulthood.
This randomized controlled study examined whether parental education was associated with cardiometabolic health from childhood to adulthood and whether it modified the effects of dietary counselling.
The Effect of Shoulder Support on Shoulder Subluxation in Stroke Survivors Based on Ultrasonography Findings: A Randomized Clinical Trial.
This single-blind randomized controlled trial assessed whether adding a standardized shoulder support to conventional rehabilitation improved shoulder subluxation, pain, upper-limb motor function, or independence in 40…
Effects of Morning Strength and Power Priming Exercises on Afternoon Physical and Cognitive Performance in Male Rugby Union Players.
This randomised, counterbalanced study examined whether morning strength and power exercises affected afternoon physical and cognitive performance in 25 male rugby union players.
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