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446 articles

November 202624

Clinical ResearchPhysical Medicine & Rehabilitation

The Effect of Shoulder Support on Shoulder Subluxation in Stroke Survivors Based on Ultrasonography Findings: A Randomized Clinical Trial.

This single-blind randomized controlled trial assessed whether adding a standardized shoulder support to conventional rehabilitation improved shoulder subluxation, pain, upper-limb motor function, or independence in 40…

Musculoskeletal CareNov 11, 2026Read summary
Clinical ResearchCardiology

Socio-economic status, cardiovascular risk factors, and coronary atherosclerosis: a SCOT-HEART trial analysis.

This post-hoc analysis of a multicentre randomised trial examined socioeconomic status (SES) in relation to coronary CT angiography (CCTA) plaque features, management, and cardiovascular outcomes.

Eur J Prev CardiolNov 11, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Imaging-Based AI for Predicting Pathological Complete Response in Esophageal Cancer After Neoadjuvant Therapy: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging-based AI models for predicting pathological complete response after neoadjuvant therapy for esophageal cancer, separating internal from external validation.

J Med Internet ResNov 11, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Conservative versus surgical management of traumatic acute subdural hematoma: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis compared surgical with conservative management of traumatic acute subdural hematoma in adults.

Neurosurg RevNov 11, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Efficacy and safety of middle meningeal artery embolisation for chronic subdural haematoma: a systematic review and meta-analysis of randomised controlled trials.

This PRISMA-compliant systematic review and meta-analysis pooled randomised controlled trials comparing middle meningeal artery embolisation (MMAE)-based treatment with standard management in adults with radiologically…

Neurosurg RevNov 11, 2026Read summary
Clinical ResearchUrologyOpen access

Diagnostic yield and early outcomes of radical prostatectomy without prior histopathologic diagnosis: a single-arm systematic review and meta-analysis.

This single-arm systematic review and random-effects meta-analysis assessed radical prostatectomy without prior histopathologic confirmation in adult men with high clinical suspicion of clinically significant prostate…

World J UrolNov 10, 2026Read summary
Clinical ResearchPulmonology

Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.

This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.

SleepNov 10, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Combined Immunotherapy and Hybrid Dose-Fraction Radiotherapy for Driver-Negative Metastatic NSCLC: A Phase II Trial with Parallel Preclinical Studies.

This single-arm, multicenter phase II trial evaluated hybrid dose-fraction radiotherapy added during first-line chemoimmunotherapy maintenance in 83 patients with stage IV driver-negative metastatic NSCLC.

Cancer Commun (Lond)Nov 10, 2026Read summary
Clinical ResearchPsychiatry

Altered effective connectivity during cognitive distancing in cognitive behavioral therapy nonresponders with depression.

This clinical trial analysis examined whether pretreatment brain connectivity during cognitive distancing was associated with cognitive behavioral therapy (CBT) response in 77 outpatients with major depressive disorder.

Psychol MedNov 9, 2026Read summary
Clinical ResearchOrthopedic Surgery

Paraspinal Muscle Quality and Functional Outcomes Following Lumbar Fusion: A Systematic Review.

This systematic review examined whether preoperative and postoperative paraspinal muscle quality is associated with patient-reported outcomes after lumbar interbody fusion, and whether findings differ between minimally…

Musculoskeletal CareNov 8, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Relaxivity Performance of Gadopiclenol Versus Gadobenate Dimeglumine In Vitro, and Liver and Brain Imaging: A Randomized Crossover Study.

This randomized intraindividual crossover study compared gadopiclenol with gadobenate dimeglumine in vitro and in liver and brain MRI.

Invest RadiolNov 7, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Retinal and choroidal changes on optical coherence tomography in pre-eclampsia: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled observational studies comparing OCT measures in women with pre-eclampsia (PE) and control groups.

Int OphthalmolNov 7, 2026Read summary
Clinical ResearchPulmonologyOpen access

Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed mucus-plug prevalence, clinical characteristics and outcomes across chronic respiratory diseases, including asthma, COPD and cystic fibrosis.

LungNov 6, 2026Read summary
Clinical ResearchUrology

Too good to be true? AI performance in CT-based urinary stone detection and classification: EAU endourology systematic review and diagnostic accuracy meta-analysis.

This systematic review and diagnostic accuracy meta-analysis assessed AI for detecting and classifying urinary stones on CT.

World J UrolNov 5, 2026Read summary
Clinical ResearchUrology

Intravesical BCG-induced granulomatous prostatitis mimicking prostate cancer in patients with non-muscle invasive bladder cancer: a systematic review.

This systematic review examined the clinical presentation of granulomatous prostatitis associated with intravesical BCG therapy for non-muscle-invasive bladder cancer.

World J UrolNov 5, 2026Read summary
Clinical ResearchNeurosurgeryOpen access

Syringomyelia secondary to degenerative spinal canal stenosis: a systematic review.

This PRISMA 2020 systematic review synthesised patient-level reports of syringomyelia associated with degenerative spinal canal stenosis, predominantly cervical spondylosis.

Neurosurg RevNov 5, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Avascular necrosis of the femur following COVID-19: an updated systematic review.

This systematic review updated evidence on avascular necrosis (AVN) of the femoral head reported after COVID-19. Searches identified 55 studies, comprising four cross-sectional studies, six retrospective studies, and 45…

Arch Orthop Trauma SurgNov 5, 2026Read summary
Clinical ResearchOncology (Medical)

Spatial Acid-Associated Niches Inform Irinotecan-Based DEB-TACE in Colorectal Liver Metastases: A Multicentre Randomized Trial.

This multicentre randomised trial combined transcriptomic and spatial analyses of colorectal liver metastases (CRLM), laboratory testing of irinotecan-eluting microspheres, and clinical evaluation in 35 patients with…

Liver IntNov 3, 2026Read summary
Clinical ResearchRadiology (Diagnostic)Open access

Radiomics performance to identify high-risk carotid artery plaques: a systematic review.

This systematic review assessed radiomics-based models for identifying high-risk carotid plaques. It included 28 studies involving 6,108 patients, 72.4% of whom were male.

Eur Radiol ExpNov 3, 2026Read summary
Clinical ResearchOncology (Medical)Open access

Coronary artery calcification is not associated with survival in advanced gastric and gastroesophageal junction cancer: a secondary analysis of the EXPAND trial.

This secondary analysis of baseline CT images from the phase III EXPAND trial assessed whether coronary artery calcification (CAC) predicted overall survival in 785 patients with unresectable locally advanced or…

J Cancer Res Clin OncolNov 3, 2026Read summary
Clinical ResearchNeurologyOpen access

Clinical, neuroimaging and electroencephalographic differences between pediatric and adult HaNDL: a systematic review and pooled individual patient analysis.

This PRISMA 2020-guided systematic review and pooled individual patient analysis compared clinical and ancillary findings in pediatric and adult patients with HaNDL, a self-limited headache syndrome with cerebrospinal…

Neurol SciNov 3, 2026Read summary
Clinical ResearchNeurosurgery

Predictive Accuracy and Procedural Benefits of Software-Enhanced Flow-Diverter Planning: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed whether software simulations improve flow-diverter (FD) planning and procedural outcomes for intracranial aneurysms compared with physician planning.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchRadiology (Diagnostic)

Imaging Modalities to Visualize Deep Cerebral Perforating Arteries: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed imaging methods for visualizing deep cerebral perforating arteries in human studies.

AJNR Am J NeuroradiolNov 3, 2026Read summary
Clinical ResearchNeurology

Microbiota-derived urolithins and cortical thickness in cognitively healthy older adults: a longitudinal MRI analysis of the WAHA trial.

This longitudinal MRI sub-study within the randomized WAHA trial examined whether changes in urinary microbiota-derived urolithins tracked with cortical-thickness changes in cognitively healthy older adults.

Food FunctNov 2, 2026Read summary

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