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557 articles
November 202624
Outcomes with Catheter-Directed Thrombolysis versus Mechanical Thrombectomy for Patients with Intermediate/High Risk Pulmonary Embolism: A Meta-Analysis of 24,090 Patients.
This meta-analysis compared catheter-directed thrombolysis (CDT) with mechanical thrombectomy (MT) in patients with intermediate- or high-risk pulmonary embolism treated with catheter-based therapies.
Multidisciplinary management of disseminated tuberculosis with tuberculous meningitis and active hepatitis B in a critically ill pregnant woman in the third trimester: a case report.
A 24-year-old woman at 30 weeks’ gestation presented with headache, vomiting, fever, and nuchal rigidity. Cerebrospinal fluid findings confirmed tuberculous meningitis, and chest CT showed diffuse miliary nodules…
Rheumatoid factor positivity in ANCA-negative eosinophilic granulomatosis with polyangiitis: cardiac mimicry, mononeuritis multiplex, and long-term outcome in a case-based systematic review.
A 42-year-old woman with long-standing asthma and rheumatoid factor (RF) of 322 IU/mL presented with myocardial infarction-like cardiac involvement despite non-obstructive coronary arteries.
Brain MRI changes following continuous positive airway pressure therapy in adults with obstructive sleep apnea: a systematic review.
This systematic review synthesized longitudinal brain MRI studies in adults with obstructive sleep apnea (OSA) before and after continuous positive airway pressure (CPAP), including comparisons with control groups.
Dirozalkib versus Crizotinib in Advanced Anaplastic Lymphoma Kinase Inhibitor-Naïve ALK -Positive Non-Small-Cell Lung Cancer: A Multicenter, Randomized Phase III Trial.
DIAMOND-2 was a multicenter, randomized, open-label phase III trial comparing dirozalkib with crizotinib in adults with ALK inhibitor-naïve, ALK-positive advanced non-small-cell lung cancer.
Effect of orofacial myofunctional therapy with auto-monitoring on the apnea-hypopnea index in patients with mild-to-moderate obstructive sleep apnea: a multicenter randomized controlled trial.
This multicenter randomized controlled trial assessed standardized orofacial myofunctional therapy (OMT) in treatment-naive adults with mild-to-moderate obstructive sleep apnea.
IgD-λ POEMS syndrome presenting with edema, pulmonary hypertension, and renal impairment: A case report.
A 38-year-old woman presented with years of intermittent leg edema, elevated creatinine, and acute worsening, followed by precapillary pulmonary hypertension, polyserous effusions, splenomegaly, lymphadenopathy, anemia…
Successful rechallenge with almonertinib and corticosteroids after gefitinib-induced interstitial lung disease: A case report and literature review.
A 53-year-old never-smoking woman with stage IV, EGFR L858R-mutant lung adenocarcinoma developed progressive dyspnea and hypoxemia after two months of gefitinib, despite an initial tumor response.
Effectiveness of a Multicomponent Digital Therapeutic Program on Inhaled Medication Adherence in Chronic Obstructive Pulmonary Disease: Pilot Randomized Controlled Trial.
This 24-week, prospective, open-label randomized controlled pilot trial evaluated a multicomponent digital program in patients with COPD prescribed pressurized metered-dose inhalers.
Mucus Plugging Across Multiple Chronic Respiratory Diseases: A Systematic Review and Meta-analysis.
This systematic review and meta-analysis assessed mucus-plug prevalence, clinical characteristics and outcomes across chronic respiratory diseases, including asthma, COPD and cystic fibrosis.
Chest physiotherapy for pneumonia in children.
This Cochrane systematic review and meta-analysis assessed randomised trials of chest physiotherapy versus usual care in hospitalised children with pneumonia.
Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.
A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.
Effect of remote patient monitoring on PAP adherence and patient-reported outcomes in obstructive sleep apnea: a comparative study.
This prospective, open-label, active-comparator randomized trial compared remote patient monitoring (RPM) with standard care (SOC) in PAP-naive adults with obstructive sleep apnea who owned a smartphone.
A phase 2a, double-blind, randomised, placebo-controlled trial of the myeloperoxidase inhibitor, mitiperstat, in participants with COPD.
This phase 2a, double-blind, randomised, placebo-controlled trial assessed mitiperstat in adults aged 40–80 years with moderate-to-severe COPD, high exacerbation risk, and ongoing dual or triple inhaled therapy.
Health-related quality of life measures in chronic pulmonary aspergillosis: a systematic review of psychometric validity.
This systematic review assessed health-related quality-of-life (HRQoL) measures and symptom scores used in chronic pulmonary aspergillosis (CPA), synthesising evidence from English-language studies published through May…
Systemic corticosteroids in critical illness: an evidence-based framework for clinical decision-making.
This systematic review qualitatively synthesized randomized trials, reviews, and meta-analyses to develop a decision framework for systemic corticosteroids in severe community-acquired pneumonia (sCAP), acute…
The Association Between Chronic Obstructive Pulmonary Disease and Postoperative Delirium: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis examined whether chronic obstructive pulmonary disease (COPD) is associated with postoperative delirium (POD) in surgical patients.
"Fatal venous thromboembolism and divergent phenotypes in DOCK8 deficiency: a three-sibling case series".
Three siblings with genetically confirmed DOCK8 deficiency had early-onset atopic dermatitis, recurrent respiratory infections, and failure to thrive. All developed bronchiectasis and severe viral infections.
Oncologic efficacy and safety of stereotactic body radiotherapy for oligometastatic non-small cell lung cancer: a systemic meta-analysis.
This systematic review and meta-analysis assessed the efficacy and safety of stereotactic body radiotherapy (SBRT) for oligometastatic non-small cell lung cancer, including analyses by oligometastatic subtype and…
Transbronchial Cryobiopsy for the Diagnosis of Peripheral Pulmonary Lesions: A Prospective Randomized Controlled Study.
This prospective, single-center randomized controlled study compared radial endobronchial ultrasound with guide-sheath-assisted transbronchial cryobiopsy (TBCB) using a 1.1-mm ultrathin probe with conventional forceps…
Pulmonary-Cardiac Involvement in a Patient with IgA Vasculitis.
A 41-year-old woman with biopsy-proven IgA nephropathy presented with progressive dyspnea, hemoptysis, and a painful purpuric rash.
Non-Small Cell Lung Carcinoma With Bilayered Architecture and TP53 Alteration: A Diagnostic Pitfall and a Potential Distinct Entity.
A 75-year-old never-smoker had a 1.1-cm pulmonary nodule with an intact bilayered architecture, including a continuous basal cell layer.
Implementing Respiratory Illness Care Pathways in General Hospitals: A Cluster Randomized Trial.
This pragmatic, multicenter cluster-randomized trial evaluated implementation of inpatient pathways for asthma, pneumonia, and bronchiolitis in US general hospitals.
Airway occlusions to measure inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation.
This multicenter randomized study assessed whether airway occlusion maneuvers can estimate inspiratory effort, respiratory drive, and lung mechanics during noninvasive ventilation (NIV).
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