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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

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FeaturedClinical ResearchPsychiatry

The efficacy of modified psychodynamic psychotherapy for patients with schizophrenia-spectrum disorders in Germany: a prospective, single-centre, assessor-blinded, parallel-group, randomised controlled trial.

Lancet PsychiatrySep 10, 2026

This randomized controlled trial evaluated the efficacy of Modified Psychodynamic Psychotherapy for Schizophrenia (MPP-S) combined with treatment as usual (TAU) in 130 outpatients with schizophrenia-spectrum disorders…

Why it matters

The study highlights the potential of psychodynamic psychotherapy to enhance psychosocial functioning in patients with schizophrenia-spectrum disorders, addressing a gap in standard care.

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Also worth knowing

Clinical ResearchPsychiatry

Comparative effectiveness of mood stabiliser monotherapy versus second-generation antipsychotic monotherapy versus combination therapy for continuation and maintenance treatment after a first episode of psychotic mania in North America, Chile, and Spain: a target trial emulation using data from the BD-CAUSAL Collaboration.

This pragmatic clinical trial evaluated the effectiveness of mood stabiliser monotherapy, second-generation antipsychotic monotherapy, and combination therapy in individuals aged 16 and older after a first episode of…

Lancet PsychiatrySep 10, 2026Read summary
Clinical ResearchPsychiatry

Effects of Digital Mental Health Screening Alone and With the Online MINDBODYSTRONG CBT-Based Program on Burnout, Depression, Anxiety, Healthy Behaviors, and Suicidal Ideation in at-Risk Nurses at 3- and 6-Months Post-Intervention: An RCT.

This randomized controlled trial evaluated the effects of a digital mental health screening program alone versus combined with the MINDBODYSTRONG CBT-based program on burnout, depression, anxiety, and suicidal ideation…

Worldviews Evid Based NursSep 10, 2026Read summary
Clinical ResearchPsychiatry

Transcranial Magnetic Stimulation for Patients with Exposure Therapy Resistant Obsessive-Compulsive Disorder (TETRO): Study Protocol for a Multicenter Randomized Controlled Trial.

This multicenter randomized controlled trial investigates the efficacy and cost-effectiveness of low-frequency (1Hz) rTMS targeting the pre-SMA as an adjunct to exposure therapy in adults with OCD who have not responded…

JMIR Res ProtocSep 9, 2026Read summary
Clinical ResearchPsychiatry

Relational care in community mental health: Evaluating staff experiences in Intensive Community Care Services (ICCS) vs treatment as usual.

This randomized controlled trial evaluated staff experiences in Intensive Community Care Services (ICCS) compared to Treatment as Usual (TAU) in community mental health.

PLoS OneSep 9, 2026Read summary
Clinical ResearchPsychiatry

Gastrointestinal Interoception and Relapse in Anorexia Nervosa.

This randomized controlled trial examined gastrointestinal interoception in 62 weight-restored females with anorexia nervosa (AN) compared to 57 healthy controls.

JAMA PsychiatrySep 1, 2026Open accessRead summary
Clinical ResearchPsychiatry

Neurometabolites and Antipsychotic Response in Psychosis: A Mega-Analysis.

This meta-analysis examined neurometabolite differences in antipsychotic nonresponders versus responders in psychosis, analyzing data from 1189 participants across 18 studies.

JAMA PsychiatrySep 1, 2026Open accessRead summary
Clinical ResearchPsychiatry

Cognitive Behavioral Therapy vs Media Literacy for Prevention of Gaming Disorder and Unspecified Internet Use Disorder: A Randomized Clinical Trial.

This randomized clinical trial evaluated the effectiveness of cognitive behavioral therapy (CBT) versus a media literacy intervention for preventing gaming disorder and unspecified internet use disorder among…

JAMA Netw OpenSep 1, 2026Open accessRead summary
Clinical ResearchPsychiatry

A Smartphone-Based Ecological Momentary Intervention for Workplace Mental Health: Randomized Controlled Trial.

This randomized controlled trial evaluated the effectiveness of Neurum, a smartphone-based intervention, in reducing workplace stress among 201 working adults over four weeks.

JMIR Mhealth UhealthSep 8, 2026Read summary
Clinical ResearchPsychiatry

Causal Relationship of Polyunsaturated Fatty Acids With Mental Disorders: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis utilized Mendelian randomization to explore the causal relationship between polyunsaturated fatty acids (PUFAs) and mental disorders (MDs) using genome-wide association study…

Nutr RevSep 6, 2026Read summary
Clinical ResearchOtolaryngology (ENT)

Comparison of therapeutic results with/without additional electroacupuncture therapy in sudden sensorineural hearing loss with anxiety or depression: A randomized controlled trial.

This randomized controlled trial evaluated the effects of adding electroacupuncture (EA) to standard pharmacotherapy in 78 patients with sudden sensorineural hearing loss (SSNHL) and comorbid anxiety or depression.

Pak J Pharm SciSep 6, 2026Read summary
Clinical ResearchPsychiatry

Implementation of Mobile Health Intervention Targeting Belongingness and Burdensomeness: An Ecological Momentary Assessment Study of Self-Injurious Thoughts and Behaviors in LGBTQ+ Individuals.

This randomized controlled trial evaluated a mobile health intervention aimed at reducing self-injurious thoughts and behaviors in LGBTQ+ individuals.

Suicide Life Threat BehavSep 6, 2026Read summary

Showing 12 of 68 publications that cleared our clinical screen in the last 14 days.

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