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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

FeaturedClinical ResearchOrthopedic Surgery

Prevention of Venous Thromboembolism after Total Hip or Knee Replacement.

N Engl J MedNov 12, 2026

This multicenter randomized comparative-effectiveness noninferiority trial compared 30 days of aspirin, warfarin, or rivaroxaban for VTE prophylaxis after elective total hip or knee arthroplasty.

Why it matters

VTE prophylaxis after hip or knee replacement requires balancing prevention of symptomatic thromboembolism against bleeding and other safety events.

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Also worth knowing

Clinical ResearchOrthopedic Surgery

Interventions for adhesive capsulitis: systematic review and network meta-analysis of randomised controlled trials.

This systematic review and network meta-analysis compared treatments for adhesive capsulitis in adults, including 189 randomised controlled trials with 12 988 participants and 59 interventions.

BMJNov 4, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Operative versus nonoperative management of olecranon fractures in older adults: a systematic review and meta-analysis.

This systematic review and meta-analysis compared operative with nonoperative management of displaced olecranon fractures in older adults.

Arch Orthop Trauma SurgNov 9, 2026Read summary
Clinical ResearchOrthopedic Surgery

Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): a randomized controlled trial.

This multicentre randomized controlled trial tested whether app-based cognitive behavioural therapy (CBT) reduced persistent postsurgical pain in adults with operatively treated extremity fractures at 11 hospitals in…

CMAJNov 9, 2026Read summary
Clinical ResearchOrthopedic Surgery

A comparison of the efficacy and safety of direct oral anticoagulants with low molecular weight heparin for venous thromboembolism prophylaxis after total hip arthroplasty : a systematic review and meta-analysis.

This systematic review and meta-analysis compared direct oral anticoagulants (DOACs) with low molecular weight heparin (LMWH) for venous thromboembolism prophylaxis after elective total hip arthroplasty.

Bone Joint JNov 1, 2026Read summary
Clinical ResearchOrthopedic Surgery

Supervised physiotherapeutic scoliosis-specific exercises provide limited additional benefit at 24 months in braced adolescents with idiopathic scoliosis: a randomized trial.

This randomized trial compared supervised Schroth-based physiotherapeutic scoliosis-specific exercises (PSSE) with self-directed general exercise in adolescents with idiopathic scoliosis receiving brace treatment.

Bone Joint JNov 1, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

Is Exercise Effective at Reducing Pain Catastrophizing in People With Chronic Nonspecific Spinal Pain? A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined whether exercise reduces pain catastrophizing in people with chronic nonspecific spinal pain.

Clin J PainNov 11, 2026Read summary
Clinical ResearchOrthopedic Surgery

Effects of Exercise Type and Duration on Pain, Function, and Quality of Life in Patients With Knee Osteoarthritis: A Systematic Review With Bayesian Network Meta-Analysis.

This systematic review with Bayesian network meta-analysis compared aerobic, resistance, and combined exercise for pain, function, and quality of life in people with knee osteoarthritis.

J Orthop Sports Phys TherNov 1, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Comparison of alignment in patients with buccally displaced maxillary canines using T-loop mechanics and continuous arch mechanics: a randomized clinical trial.

This parallel, two-arm randomized clinical trial compared T-loop mechanics (TLM) with continuous arch mechanics (CAM) for aligning maxillary anterior teeth in 26 patients with unilateral or bilateral buccally displaced…

Clin Oral InvestigNov 10, 2026Read summary
Clinical ResearchOrthopedic SurgeryOpen access

Impact of early versus delayed mobilization after arthroscopic rotator cuff repair in small and medium-sized tears: a prospective randomized study.

This prospective randomized study compared early with delayed mobilization after arthroscopic single-row knotless repair of small and medium full-thickness supraspinatus tears in 70 patients aged 20–70 years.

J Orthop Surg ResNov 10, 2026Read summary
Clinical ResearchPhysical Medicine & Rehabilitation

The Effect of Exercise Training on Individuals With Osteoporotic Vertebral Fracture: A Randomized Controlled Trial.

This single-centre, open-label randomised controlled trial evaluated a 12-week supervised exercise programme in adults with osteoporotic vertebral fractures.

Physiother Res IntNov 8, 2026Read summary
Clinical ResearchPlastic Surgery

Current Evidence of Digital and Hand Replantation Following Cold Ischemia or Cryopreservation: A Systematic Review.

This systematic review examined published outcomes after digit or hand replantation when preservation was at or below 10°C or exceeded 6 hours.

MicrosurgeryNov 12, 2026Read summary

Showing 12 of 24 publications that cleared our clinical screen in the last 14 days.

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