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232 articles

November 202611

Clinical ResearchOphthalmologyOpen access

Retinal and choroidal changes on optical coherence tomography in pre-eclampsia: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled observational studies comparing OCT measures in women with pre-eclampsia (PE) and control groups.

Int OphthalmolNov 7, 2026Read summary
Clinical ResearchOphthalmology

Risk of retinal vascular occlusion following COVID-19 vaccination: A meta-analysis of nearly 15 million individuals.

This systematic review and meta-analysis assessed retinal vascular occlusion after COVID-19 vaccination using five observational studies with 14,877,781 reported participants.

Medicine (Baltimore)Nov 6, 2026Read summary
Clinical ResearchOphthalmology

The impact of nutrition on glaucoma progression: evidence from systematic literature review and meta-analysis.

This systematic review and meta-analysis assessed whether dietary factors or nutritional supplements affect glaucoma progression in adults.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Endoscopic dacryocystorhinostomy with versus without silicone intubation in chronic dacryocystitis: a comparative meta-analysis.

This systematic review and meta-analysis compared endoscopic dacryocystorhinostomy (EN-DCR) with versus without silicone intubation for chronic dacryocystitis.

Int OphthalmolNov 5, 2026Read summary
Clinical ResearchOphthalmologyOpen access

The risk of rhegmatogenous retinal detachment associated with topical pilocarpine: a systematic review.

This systematic review assessed whether topical pilocarpine is associated with rhegmatogenous retinal detachment (RRD) in patients aged 40 years or older, synthesising 10 comparative studies.

Int OphthalmolNov 2, 2026Read summary
Clinical ResearchOphthalmology

Visual Perceptual Learning Based on Adaptive Contrast Detection Training Enhances Vision and Contrast Sensitivity in Diabetic Retinopathy.

This randomized controlled trial evaluated 3-month home-based visual perceptual learning (VPL) in people with diabetic retinopathy who had received routine therapies.

Invest Ophthalmol Vis SciNov 2, 2026Read summary
Clinical ResearchOphthalmology

Randomized Single-Masked Study of Preservative-Free Versus Preserved Hyaluronic Acid in Dry Eye Disease.

This randomized, single-masked, 6-month trial compared preservative-free hyaluronic acid (PF HA) with benzalkonium chloride-preserved hyaluronic acid (BAK HA) in 47 patients with dry eye disease; 43 completed the study.

Transl Vis Sci TechnolNov 2, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Dexamethasone Eye Drops to Prevent Treatment-Requiring Retinopathy of Prematurity: The DROPROP Randomized Clinical Trial.

The DROPROP double-masked, multicentre randomised clinical trial tested whether topical dexamethasone could prevent progression to treatment-requiring type 1 retinopathy of prematurity (ROP) in preterm infants born…

JAMA PediatrNov 1, 2026Read summary
Clinical ResearchOphthalmology

First-in-Human Regulatory T Cell-Derived Exosomes Plus Ranibizumab for Refractory nAMD.

This single-centre, prospective, open-label phase 1a dose-escalation trial evaluated the safety and maximum tolerated dose of intravitreal autologous regulatory T cell-derived exosomes (TregExo) coformulated with…

J Extracell VesiclesNov 1, 2026Read summary
Clinical ResearchOphthalmology

In-the-Bag Stability of a New Hydrophilic Acrylic Toric Intraocular Lens.

This single-centre, prospective interventional clinical trial assessed in-the-bag stability of the RayOne EMV toric intraocular lens in 119 eyes of 79 patients with age-related cataract over 6 months.

J Refract SurgNov 1, 2026Read summary
Clinical ResearchOphthalmology

Anterior Chamber Depth Changes: After Phacoemulsification in Eyes With Pseudoexfoliation Syndrome Versus Control Eyes: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis compared anterior chamber depth (ACD) before and after phacoemulsification in eyes with pseudoexfoliation syndrome (PEX) and control eyes.

J Refract SurgNov 1, 2026Read summary

October 202613

Clinical ResearchOphthalmologyOpen access

Toxoplasmosis-associated optic neuropathies: a systematic review and meta-analysis of clinical characteristics, diagnosis, and outcomes.

This systematic review and meta-analysis examined optic neuropathies associated with ocular toxoplasmosis (OT), combining observational studies and case reports.

Int OphthalmolOct 31, 2026Read summary
Clinical ResearchOphthalmology

Evaluation of digital binocular therapies for amblyopia after refractive adaptation in treatment-naive children aged 3-13 years: A systematic review and meta-analysis of randomised controlled trials.

This systematic review and meta-analysis of randomised controlled trials assessed digital binocular therapies versus patching for visual acuity improvement in treatment-naive children aged 3–13 years with unilateral…

PLoS OneOct 29, 2026Read summary
Clinical ResearchOphthalmology

Pars plana vitrectomy with silicone oil versus pars plana vitrectomy alone for postoperative endophthalmitis: A randomized controlled trial.

This prospective randomized controlled trial compared pars plana vitrectomy (PPV) with 1000-cSt silicone oil (SO) tamponade against PPV alone in 40 eyes with severe post-phacoemulsification endophthalmitis unresponsive…

Indian J OphthalmolOct 28, 2026Read summary
Clinical ResearchPreventive Medicine / Public Health

Association of Screen Time With Physical and Mental Health in University Students: Systematic Review and Meta-Analysis.

This systematic review and meta-analysis examined screen-time duration and physical and mental health outcomes in university students aged 17 years or older.

J Med Internet ResOct 26, 2026Read summary
Clinical ResearchOphthalmology

Influence of capsular tension ring implantation on dynamic in vivo capsular apposition and intraocular lens behavior in highly myopic eyes.

This prospective randomized clinical trial assessed whether capsular tension ring (CTR) implantation affects capsular apposition and intraocular lens (IOL) behavior after cataract surgery in highly myopic eyes.

J Cataract Refract SurgOct 24, 2026Read summary
Clinical ResearchOphthalmology

EVALUATING THE EFFICACY AND SAFETY OF TOPICAL DIFLUPREDNATE IN PATIENTS WITH CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

This pilot, open-label randomized controlled trial compared topical difluprednate, oral eplerenone, and observation in adults with chronic or relapsing central serous chorioretinopathy.

RetinaOct 21, 2026Read summary
Clinical ResearchOphthalmology

EFFICACY AND SAFETY OF SUBTHRESHOLD LASER IN PATIENTS WITH ACUTE CENTRAL SEROUS CHORIORETINOPATHY: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed the efficacy and safety of subthreshold laser for acute central serous chorioretinopathy (CSC), including six randomized controlled trials with 401 participants.

RetinaOct 21, 2026Read summary
Clinical ResearchOphthalmology

ULTRAWIDE-FIELD COLOR FUNDUS IMAGES AND ARTIFICIAL INTELLIGENCE FOR DIAGNOSIS OF DIABETIC RETINOPATHY: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed artificial intelligence (AI) for diabetic retinopathy (DR) evaluation using ultrawide-field fundus images.

RetinaOct 21, 2026Read summary
Clinical ResearchRheumatologyOpen access

Association between rheumatic diseases and glaucoma risk: a systematic review and meta-analysis of 5.7 million individuals.

This systematic review and meta-analysis examined glaucoma occurrence and risk among people with rheumatic diseases (RD), drawing on 18 studies with 5,766,143 participants.

Int OphthalmolOct 21, 2026Read summary
Clinical ResearchOphthalmology

Cost-effectiveness of monotherapy and combination therapy for myopia control in Chinese children.

This network meta-analysis and decision-analytic Markov model assessed the cost-effectiveness of 16 myopia-control strategies for Chinese children and adolescents, modelling eight-year-old children over eight years.

J Glob HealthOct 19, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Full-spectrum LED screen-bar lighting as an adjunct to artificial tears in visual display terminal-related dry eye: a randomized study.

This prospective, randomised, single-centre study assessed whether full-spectrum screen-bar lighting adds benefit to artificial tears in 66 participants with newly diagnosed visual display terminal-related dry eye and…

Int OphthalmolOct 18, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Evaluating Long-Term Effectiveness and Safety of Glaucoma Surgical Innovations: A Systematic Review.

This systematic review assessed long-term effectiveness, safety reporting, and study quality for glaucoma surgical innovations introduced since 2004.

J GlaucomaOct 16, 2026Read summary
Clinical ResearchOphthalmology

Comparative Efficacy and Safety of Systemic Immunomodulatory Therapies for Non-Infectious Uveitis: A Systematic Review With Pairwise and Network Meta-Analyses.

This systematic review and network meta-analysis compared systemic immunomodulatory therapies for non-infectious uveitis (NIU), including evidence from seven studies with 992 participants: six randomised trials and one…

PharmacotherapyOct 15, 2026Read summary

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