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726 articles
November 202624
Primary Synovial Sarcoma of the Thyroid Gland Presenting With Early Pulmonary Metastasis: Diagnostic Pathway, SS18 Gene Fusion Confirmation, and Clinical Course.
A 47-year-old woman presented with dysphagia and a left-sided neck mass. Initial fine-needle aspiration was non-diagnostic; repeat sampling suggested a spindle cell neoplasm.
Measles-like hypermutation of a Newcastle disease virus drives fatal encephalitis during BCMA × CD3 T-cell-redirecting immunotherapy.
A patient with multiple myeloma receiving maintenance teclistamab, daratumumab, and lenalidomide developed rapidly progressive brainstem-cerebellar encephalitis.
Impact of nasogastric administration using the simple suspension method on serum tirabrutinib levels: A case report.
An 82-year-old man with relapsed primary central nervous system lymphoma began tirabrutinib at 320 mg/day while fasting. As dysphagia progressed, administration changed from swallowing tablets to nasogastric delivery by…
Multiorgan [ 18 F]florbetapir PET/CT uptake in multiple myeloma-associated systemic AL amyloidosis: a case report.
A 77-year-old man with multiple myeloma underwent whole-body [18F]florbetapir PET/CT because AL amyloidosis was suspected. The scan showed prominent tracer retention in the myocardium, thyroid, lungs, parotid glands…
Multifocal intradural extramedullary myxopapillary ependymoma of the spine.
A 34-year-old man presented with sudden severe non-radicular low-back pain but no neurological deficit. MRI showed multiple enhancing intradural extramedullary lesions from T12-L1 to S1; the dominant T12-L1 lesion…
Progression-Associated Loss of SMARCB1/INI1 Expression in Mismatch Repair-Deficient Glioblastoma.
A patient with mismatch repair-deficient glioblastoma had a recurrent tumor in which testing identified a second SMARCB1 mutation and complete loss of SMARCB1/INI1 protein expression.
Successful rechallenge with almonertinib and corticosteroids after gefitinib-induced interstitial lung disease: A case report and literature review.
A 53-year-old never-smoking woman with stage IV, EGFR L858R-mutant lung adenocarcinoma developed progressive dyspnea and hypoxemia after two months of gefitinib, despite an initial tumor response.
Pulmonary sarcomatoid carcinoma with METex14 mutation and high PD-L1: A case report.
A previously healthy 54-year-old man presented with persistent cough and diminished breath sounds over the right upper lung.
Primary splenic angiosarcoma initially diagnosed as littoral cell angioma: A case report of a diagnostic pitfall.
A 71-year-old woman presented with left upper abdominal pain, severe anemia, thrombocytopenia, and a splenic lesion. After splenectomy, the lesion was initially diagnosed as littoral cell angioma; a separate hepatic…
Synchronous hepatocellular carcinoma and nasopharyngeal carcinoma in a patient with chronic hepatitis B: A case report and literature review.
A 63-year-old Chinese man with chronic hepatitis B was found on routine screening to have a liver mass and reported nasal obstruction.
Postoperative Neuromuscular Paresis and Overlap Syndrome Related to Immune Checkpoint Inhibitors: A Case Report.
A patient receiving immune checkpoint inhibitor therapy developed extremity paresis after proximal humerus resection and reconstruction.
Dexmedetomidine with transition to oral clonidine for stabilization of refractory agitation: A case report.
A 45-year-old man with metastatic medullary thyroid carcinoma was admitted to a palliative care unit with severe opioid-refractory pain, delirium, and agitation that prevented palliative radiation.
Resolution of Severe Jaundice Following Hepatic Artery Infusion of Bevacizumab and 5-Fluorouracil With Oral Regorafenib in Metastatic Colorectal Cancer：A Case Report.
A patient with sigmoid colon cancer and recurrent liver metastases, previously treated with surgery, systemic chemotherapy, transcatheter arterial chemoembolization, and radiotherapy, presented with severe jaundice.
A rare neurological adverse event of palbociclib: a chronic inflammatory demyelinating polyneuropathy (CIDP) mimic.
A 43-year-old woman with metastatic HR-positive/HER2-negative breast cancer developed progressive, asymmetric weakness and sensory symptoms about two weeks after starting palbociclib.
Coexistence of ARNT::ALK and TPM3::ALK doublegene fusion in an ALK-rearranged renal cell carcinoma with osseous metaplasia.
An adult patient had an ALK-rearranged renal cell carcinoma. The tumor showed varied growth patterns in a mucinous background, with a small peripheral focus of osseous metaplasia.
Imaging and Clinical Features of Secondary Spinal Cord Lymphoma: A 2-Center Case Series.
This two-center case series describes 18 cases of secondary spinal cord lymphoma. The authors examined spinal MRI findings and their relationship to intracranial disease, systemic lymphoma, and clinical features.
Duodenal Adenocarcinoma Recurrence Limited to the Choledochojejunostomy After Pancreaticoduodenectomy: A Case Suggesting Intraluminal Implantation With a Distinct Mucin Phenotypic Shift.
A 59-year-old man developed recurrence at the choledochojejunostomy 27 months after pancreaticoduodenectomy for duodenal adenocarcinoma, despite five surgically created raw surfaces.
Rare Sites of Metastases to the Breast and Integumentary System in Advanced Cervical Cancer at Initial Presentation in Eastern Uganda: A Case Report.
A 72-year-old woman in Uganda presented after 13 months of intermittent postmenopausal bleeding and abnormal vaginal discharge, despite repeated treatment for presumed urinary and sexually transmitted infections.
Multidisciplinary Single Stage Surgical Management of Advanced Breast Carcinoma With Concomitant Left Atrial Myxoma.
A 58-year-old woman with locally advanced invasive mucinous breast carcinoma had a progressive fungating mass despite neoadjuvant chemotherapy and radiotherapy.
Angiosarcoma in the Setting of Vascular Procedures: A Systematic Review and Our Experiences.
Angiosarcoma is a rare, aggressive endothelial malignancy with a poor prognosis; diagnosis is often delayed by vague symptoms, nonspecific imaging, and challenging histopathology.
Catatonic signs during delirium in leptomeningeal melanoma: Treatment trade-offs in end-of-life care.
A man in his late 30s with metastatic melanoma involving the leptomeninges and brain developed fluctuating arousal, inattention, disorientation, mutism, immobility, staring, withdrawal, and waxy flexibility.
Concomitant Robotic Pericardial Window and Mediastinal Tumour Biopsy Under Intraoperative Ultrasound Guidance.
An 83-year-old woman presented with an undiagnosed mediastinal mass and a symptomatic, loculated pericardial effusion. She underwent a robotic pericardial window and mediastinal tumour biopsy performed together under…
Children of advanced cancer patients need better support: A case report.
This case study describes a parent with advanced cancer and minor children who needed support in discussing the diagnosis, preparing the children for the possibility of death, and addressing anticipatory grief.
Pediatric suprasellar primary CNS lymphoma with cavernous sinus invasion and ischemic stroke: a case report and systematic review.
A 12-year-old immunocompetent girl presented with high fever, severe headache, and diplopia, followed by rapid neurological deterioration.
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