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Important medical research and remarkable case reports worth knowing.

Selected from high-relevance medical literature published in the last 14 days.

AllClinical ResearchCase Reports
FeaturedClinical ResearchNeurology

Tenecteplase Before Thrombectomy at 4.5 to 24 Hours for Basilar Artery Occlusion: The ATTENTION LATE Randomized Clinical Trial.

JAMANov 3, 2026Open access

This multicenter, open-label, blinded-endpoint randomized clinical trial compared intravenous tenecteplase before endovascular thrombectomy (EVT) with EVT alone in patients with moderate to severe basilar artery…

Why it matters

For patients with moderate to severe basilar artery occlusion presenting in this late time window to EVT-capable centers, the trial found no functional-outcome advantage from adding intravenous tenecteplase before…

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Also worth knowing

Clinical ResearchNeurology

Severity-Based Triage for Direct Transportation to Nearest Comprehensive Stroke Center: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed prehospital bypass of the nearest stroke center for direct transport to a more distant comprehensive stroke center in patients with suspected stroke.

NeurologyNov 10, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Efficacy of Technology-Augmented Behavioral Counseling for Risky Firearm Behaviors: A Randomized Clinical Trial.

This two-arm randomized clinical trial tested IntERact, a 30-day program combining telehealth behavioral counseling and tailored smartphone content, against enhanced usual care among 373 emergency department patients…

JAMA PediatrNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Telehealth Treatment of Anxiety in Patients With Low-Risk Chest Pain in the Emergency Department: The PACER Randomized Clinical Trial.

The PACER multicentre, three-group randomised comparative effectiveness trial tested peer-supported internet-based cognitive behavioural therapy (iCBT) and therapist-delivered telehealth CBT against primary care…

JAMA Intern MedNov 1, 2026Read summary
Clinical ResearchNeurosurgery

Salovum® reduces mortality in isolated severe traumatic brain injury: a randomized phase II trial.

This prospective, double-blind, placebo-controlled phase II randomized trial tested Salovum® in adults with isolated severe traumatic brain injury receiving intracranial pressure monitoring and neurointensive care at a…

BrainNov 4, 2026Read summary
Clinical ResearchNephrology

Thrombin-antithrombin complex and fibrinogen predict microangiopathic acute kidney injury in patients with traumatic injuries.

This secondary analysis of a single-center randomized controlled trial examined whether early coagulation and fibrinolysis biomarkers were associated with acute kidney injury (AKI) in adults with severe traumatic…

Blood AdvNov 12, 2026Read summary
Clinical ResearchEmergency Medicine

Efficiency of Rescue Paramedic Hoist versus Underslung Antenna in Helicopter-Based Avalanche Searches: A Randomized Trial.

This randomized experimental field trial compared helicopter-based avalanche transceiver searches using an underslung antenna or a hoisted rescue paramedic with a handheld transceiver.

Prehosp Disaster MedNov 5, 2026Read summary
Clinical ResearchEmergency Medicine

Performance of the i-Gel Versus King LT-D by Combat Medics Under Simulated Tactical Conditions: A Prospective Randomized Crossover Study.

This prospective randomized crossover study compared i-gel and King LT-D placement by active-duty combat medics after exertion while wearing full combat gear, using a high-fidelity manikin.

Mil MedNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Prehospital Pediatric Ventilation Quality Following Use of a Feedback Device: A Randomized Study.

This multicenter, single-anonymized randomized crossover simulation study assessed pediatric manual ventilation by EMS clinicians at 5 agencies across 3 US metropolitan sites.

PediatricsNov 1, 2026Read summary
Clinical ResearchEmergency Medicine

Short-Term Pain Outcomes of Trigger Point Injection Versus Dry Needling for Acute Myofascial Low Back Pain in the Emergency Department: A Prospective Randomized Comparative Study.

This prospective randomized comparative study evaluated trigger point injection versus dry needling for acute myofascial low back pain in emergency department patients.

Med Sci MonitNov 1, 2026Read summary
Clinical ResearchEmergency MedicineOpen access

Pain-Related Outcome Domains and Measures in Randomized Controlled Trials of Treatment for Acute Abdominal Pain: A Systematic Review.

This PRISMA-guided systematic review mapped pain-related outcome domains and measures in randomized controlled trials of acute abdominal pain treatment.

Eur J PainNov 1, 2026Read summary
Case ReportEmergency Medicine

Acute Ethylene Glycol Poisoning Following Accidental Mineral Oil Ingestion With Severe Metabolic Acidosis, Acute Kidney Injury, Respiratory Failure, and Delayed Neurological Sequelae: A Case Report.

A 57-year-old man became dizzy, vomited, and developed altered consciousness progressing to coma after accidentally ingesting mineral oil containing ethylene glycol.

Am J Case RepNov 11, 2026Read case

Showing 12 of 20 publications that cleared our clinical screen in the last 14 days.

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