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1357 articles
November 202624
Effect of remote patient monitoring on PAP adherence and patient-reported outcomes in obstructive sleep apnea: a comparative study.
This prospective, open-label, active-comparator randomized trial compared remote patient monitoring (RPM) with standard care (SOC) in PAP-naive adults with obstructive sleep apnea who owned a smartphone.
A phase 2 study of tipifarnib in children and young adults with tumors harboring HRAS genomic alterations: NCI-COG Pediatric MATCH trial (APEC1621M).
This phase 2 NCI-COG Pediatric MATCH study evaluated intermittent oral tipifarnib in children and young adults with relapsed or refractory solid tumors carrying specified HRAS mutations.
Clinical Evidence for Adding Chaiqin Chengqi Decoction to Acute Pancreatitis Care: A Systematic Review and Meta-analysis of Randomized Trials.
This systematic review and meta-analysis assessed randomized trials of Chaiqin Chengqi Decoction (CQCQD) added to conventional care for acute pancreatitis. Nineteen trials involving 1,824 participants were included.
Clinical outcomes in various coronary artery bypass grafting techniques: A systematic review and network meta-analysis.
This systematic review and frequentist network meta-analysis compared conventional, minimally invasive, and robotic coronary artery bypass grafting (CABG), including nine sub-techniques, using observational studies and…
Long-term effects of a parenting program for advanced cancer: A randomized controlled trial.
This randomized controlled trial evaluated a telephone-delivered, five-session parenting education program for parents with advanced, non-curable cancer who were raising children.
Thoracic epidural versus paravertebral blockade for reducing chronic post-thoracotomy pain (TOPIC-2): open label, parallel group, superiority, multicentre, randomised controlled trial.
This open-label, multicentre, parallel-group superiority randomised trial compared perioperative paravertebral blockade with thoracic epidural in adults undergoing thoracotomy at 15 UK centres.
Targeting hormone conversion through dietary fiber improves polyendocrine metabolic ovarian syndrome.
This randomized controlled clinical trial examined a combination of inulin, resistant starch, and β-glucan in patients with polyendocrine metabolic ovarian syndrome (PMOS).
Prevalence of generalized joint hypermobility, hypermobility spectrum disorders and Ehlers-Danlos syndrome: systematic review and meta-analysis.
This systematic review and meta-analysis assessed the prevalence of generalized joint hypermobility (GJH), hypermobility spectrum disorder (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS).
Too good to be true? AI performance in CT-based urinary stone detection and classification: EAU endourology systematic review and diagnostic accuracy meta-analysis.
This systematic review and diagnostic accuracy meta-analysis assessed AI for detecting and classifying urinary stones on CT.
Efficiency of Rescue Paramedic Hoist versus Underslung Antenna in Helicopter-Based Avalanche Searches: A Randomized Trial.
This randomized experimental field trial compared helicopter-based avalanche transceiver searches using an underslung antenna or a hoisted rescue paramedic with a handheld transceiver.
A phase 2a, double-blind, randomised, placebo-controlled trial of the myeloperoxidase inhibitor, mitiperstat, in participants with COPD.
This phase 2a, double-blind, randomised, placebo-controlled trial assessed mitiperstat in adults aged 40–80 years with moderate-to-severe COPD, high exacerbation risk, and ongoing dual or triple inhaled therapy.
Syringomyelia secondary to degenerative spinal canal stenosis: a systematic review.
This PRISMA 2020 systematic review synthesised patient-level reports of syringomyelia associated with degenerative spinal canal stenosis, predominantly cervical spondylosis.
Feasibility and tolerability of combining 6 Hz transcranial alternating current stimulation (tACS) at 3.2 mA and digital cognitive training in older adults with mild cognitive impairment.
This randomized-trial study evaluated feasibility and tolerability of five daily sessions of 6-Hz, 3.2-mA transcranial alternating current stimulation (tACS) during digital cognitive training (DCT) in older adults with…
The impact of nutrition on glaucoma progression: evidence from systematic literature review and meta-analysis.
This systematic review and meta-analysis assessed whether dietary factors or nutritional supplements affect glaucoma progression in adults.
Resistance training and protein supplementation in patients with incurable gastroesophageal cancer: a randomized feasibility trial.
This open-label, parallel-group randomized feasibility trial assessed resistance training plus protein supplementation during first-line chemotherapy in patients with incurable gastroesophageal cancer.
Suction versus traditional ureteral access sheaths in retrograde intrarenal surgery: an updated systematic review and meta-analysis of stone-free rates and complications.
This updated systematic review and meta-analysis compared suction with traditional ureteral access sheaths during retrograde intrarenal surgery in adults.
Combining quizartinib with intensive chemotherapy for older patients with newly diagnosed AML: results of the UK NCRI AML18 trial.
The multicentre randomised UK NCRI AML18 trial evaluated quizartinib after intensive chemotherapy, with or without maintenance, in patients older than 60 years with newly diagnosed AML or high-risk myelodysplastic…
Photobiomodulation for radiotherapy-induced dysgeusia in head and neck cancer patients: a pilot randomized clinical trial.
This pilot randomized clinical trial compared photobiomodulation (PBM) with zinc sulfate for radiotherapy-induced dysgeusia in 16 patients with head and neck cancer.
Intravesical BCG-induced granulomatous prostatitis mimicking prostate cancer in patients with non-muscle invasive bladder cancer: a systematic review.
This systematic review examined the clinical presentation of granulomatous prostatitis associated with intravesical BCG therapy for non-muscle-invasive bladder cancer.
Efficacy of cognitive behavioral therapy for anxiety and depression symptoms in Parkinson's disease patients: a systematic review and meta-analysis.
This systematic review and meta-analysis assessed cognitive behavioral therapy (CBT) for anxiety and depressive symptoms in adults with Parkinson’s disease (PD), pooling 21 randomized controlled trials involving 892…
Differential changes in cervical proprioception and motor imagery following structured imagery training in chronic neck pain.
This clinical trial examined whether a 4-week telerehabilitation program combining lateralization and implicit motor imagery training affected cervical proprioception and related outcomes in 17 people with chronic neck…
Sequential therapy with anlotinib and radioiodine for distant metastatic differentiated thyroid cancer: a phase II clinical trial.
This prospective, single-arm phase II trial evaluated sequential anlotinib and radioiodine (RAI) in patients with measurable distant metastatic differentiated thyroid cancer (DTC).
Plozasiran for Severe Hypertriglyceridemia and Risk of Pancreatitis.
Two double-blind, placebo-controlled randomized trials evaluated plozasiran in 757 adults with severe hypertriglyceridemia.
Effectiveness of nurse-led hypertension interventions on retention, adherence, and blood pressure control among adults in low- and middle-income countries: A systematic review.
This systematic review assessed nurse-led hypertension interventions in primary care among adults in low- and middle-income countries, examining retention, medication adherence, and blood pressure.
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