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557 articles
September 202624
Coinfection of Pneumocystis jirovecii and Aspergillus fumigatus in the lung: A case report.
A 66-year-old male with mantle cell lymphoma and a history of corticosteroid therapy presented with worsening pulmonary symptoms.
Effect of esketamine on postoperative pulmonary complications after radical surgery for lung cancer: A randomized double-blind controlled trial.
This randomized controlled trial evaluated the effect of perioperative esketamine on postoperative pulmonary complications (PPCs) in 80 patients undergoing thoracoscopic radical lung cancer surgery.
Cardiorespiratory adaptations to high-intensity interval training in young boxers: A randomized controlled study.
This randomized controlled trial examined the effects of a 4-week high-intensity interval training (HIIT) regimen on cardiorespiratory fitness in 16 trained young boxers.
Early-life serum protein profiles associated with bronchopulmonary dysplasia in extremely preterm infants.
This multicenter randomized controlled trial studied early serum protein profiles in 176 extremely preterm infants (<28 weeks gestational age) to identify associations with bronchopulmonary dysplasia (BPD).
Addition of once-weekly aerobic training to ongoing resistance training in a patient with prior lobectomy for congenital pulmonary airway malformation: A case report.
A man who had undergone right upper lobectomy for congenital pulmonary airway malformation (CPAM) at 6 months of age presented in adulthood with restrictive ventilatory impairment, including markedly reduced FVC and…
Duration of effectiveness of tuberculosis preventive treatment across various tuberculosis burden settings: a systematic review and individual-participant meta-analysis.
This systematic review and individual-participant meta-analysis pooled data from 84 128 tuberculosis-infected close contacts in 44 cohort studies across 24 countries to assess how long tuberculosis preventive treatment…
Effects of PERMISSive lung-protective ventilation on outcome in critically ill, invasively ventilated patients (PERMISS): protocol for a feasibility and safety randomised clinical trial.
The PERMISS pilot study is a multicenter randomized clinical trial assessing the feasibility and safety of a permissive lung-protective ventilation strategy with a lower respiratory rate in critically ill, invasively…
Factors affecting hand hygiene adherence among critical care healthcare workers: A systematic review.
This PRISMA-guided systematic review examined factors associated with hand hygiene adherence among healthcare workers in intensive care units and emergency departments.
Factors associated with unplanned re-admission after elective gastroenterological surgery: an analysis of 1824 participants with clean-contaminated wounds enrolled in two randomized controlled trials for the prevention of surgical site infection.
This analysis examined factors associated with unplanned readmission within 30 days of discharge among patients undergoing elective gastroenterological surgery with clean-contaminated wounds.
Impact of neoprene wetsuits on lung volumes and work of breathing: implications for military diver safety and performance.
This randomized controlled trial assessed the effects of neoprene wetsuits on lung function in 31 healthy male divers. Results indicated significant reductions in forced vital capacity (FVC) by 2.8% and functional…
Comprehensive application of artificial intelligence in preserved ratio impaired spirometry: A systematic literature review.
This systematic review examined the application of artificial intelligence (AI) in diagnosing Preserved Ratio Impaired Spirometry (PRISm) across eleven studies.
ECG-based artificial intelligence for obstructive sleep apnea detection: a mechanism-oriented diagnostic meta-analysis.
This meta-analysis evaluated the diagnostic performance of AI models using ECG signals for detecting obstructive sleep apnea (OSA) across 13 studies.
Ocrelizumab-related organizing pneumonia in multiple sclerosis: insights from a case series and literature review.
A case series of five multiple sclerosis patients treated with ocrelizumab developed organizing pneumonia (OP) after a mean treatment duration of 5.1 years.
Analgesic Efficacy of Different Doses of Esketamine as an Adjuvant to Ropivacaine for Thoracoscopy-Guided Thoracic Paravertebral Block After Thoracoscopic Radical Resection for Lung Cancer: A Prospective Randomized Controlled Trial.
Thoracoscopy-guided thoracic paravertebral block (TG-TPVB) is a new analgesia technique; however, the duration of a single TG-TPVB is short.
Integrated Telehealth Rehabilitation and Quality of Life in Mechanically Ventilated Adults: A Randomized Clinical Trial.
This randomized clinical trial evaluated the impact of an integrated telehealth rehabilitation program on health-related quality of life in 1916 adults with acute hypoxemic respiratory failure requiring mechanical…
Acetazolamide to prevent ventilatory drive withdrawal in REM sleep apnoea: a randomised controlled trial.
This randomized controlled trial evaluated the effects of acetazolamide on REM-predominant obstructive sleep apnoea (OSA) in 11 participants.
New pathogenic PTPN2 variant leading to childhood interstitial lung disease.
A 4-year-old boy presented with childhood interstitial lung disease, which was linked to a newly identified pathogenic variant in the PTPN2 gene.
Pulmonary Sequestration Masquerading as Bronchiectasis in an Adult: A Case of Diagnostic Dilemma and Literature Review.
A 45-year-old woman presented with fever, cough, and right-sided chest pain, initially diagnosed with bronchiectasis. After treatment, she developed recurrent hemoptysis.
The Effects of Intermittent Hypoxic Training Strategies on Maximal Oxygen Uptake in Healthy Humans: A Meta-analysis with Meta-regression.
This systematic review and random-effects meta-analysis examined controlled studies of intermittent hypoxic training and maximal oxygen uptake (VO₂ max) in healthy athletes and non-athletes.
Accuracy of type 2 inflammatory biomarkers to diagnose asthma in adults and children: a meta-analysis of 30 studies with prospective validation in an adult primary care cohort.
This systematic review and meta-analysis assessed fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC) for diagnosing asthma in adults and children with suspected asthma and normal spirometry, with…
Comparative efficacy and safety of first, second, and third-generation EGFR tyrosine kinase inhibitors in treatment-naïve EGFR-mutant advanced non-small cell lung cancer: a systematic review and network meta-analysis of randomized controlled trials.
This systematic review and network meta-analysis evaluated the efficacy and safety of first, second, and third-generation EGFR tyrosine kinase inhibitors (TKIs) in treatment-naïve patients with EGFR-mutant advanced…
High-Flow Nasal Oxygen Versus Conventional Oxygen Therapy and Non-Invasive Ventilation for Acute Respiratory Failure in the Emergency Department: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis evaluated high-flow nasal oxygen (HFNO) versus conventional oxygen therapy (COT) and non-invasive ventilation (NIV) for acute respiratory failure in adults in the emergency…
Tambotatug Pelitecan in Small-Cell Lung Cancer after Platinum-Based Therapy.
This phase 3, multicenter, open-label randomized trial compared tambotatug pelitecan with topotecan in patients whose small-cell lung cancer had progressed after first-line platinum-based therapy.
A Randomized Four-Period Cross-Over Phase I Study to Assess Bioavailability, Bioequivalence, and Tolerability of IHL-42X Compared with the Reference Drugs in Healthy Volunteers.
This phase I, randomized four-period crossover study assessed bioavailability, bioequivalence, food effects, and tolerability of IHL-42X—a combination of dronabinol and acetazolamide—in healthy volunteers at two…
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