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1320 articles

October 202624

Clinical ResearchGeriatrics

Agreement Between In-Person and Telephone Application of the Informant Questionnaire on Cognitive Decline in the Elderly.

This methodological study assessed agreement between in-person and telephone administration of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), completed by caregivers or family members of older…

PsychogeriatricsOct 22, 2026Read summary
Clinical ResearchNeurology

Antidopaminergic Medications and Clinical Outcomes in Huntington Disease: Evidence From the PROOF-HD Placebo-Controlled Trial.

This post hoc analysis of the placebo arm of the randomized PROOF-HD trial examined associations between antidopaminergic medication (ADM) use and clinical outcomes in adults with Huntington disease.

NeurologyOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Prediction of death by neurologic criteria in patients with non-traumatic acute brain injury: a systematic review and meta-analysis.

This systematic review and meta-analysis examined predictors of death by neurologic criteria (DNC) after non-traumatic acute brain injury.

BMC NeurolOct 22, 2026Read summary
Case ReportNeurology

Tuberculosis-Associated Longitudinally Extensive Transverse Myelitis.

A 51-year-old man with a year of chronic non-productive cough and about 20 days of fever and headache presented with encephalopathy but no focal neurological deficits.

Am J Case RepOct 22, 2026Read case
Clinical ResearchNeurologyOpen access

Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.

This analysis of data from the ADHERE randomized controlled trial estimated the minimal important difference (MID) in EQ-5D-5 L utility values for patients with chronic inflammatory demyelinating polyradiculoneuropathy…

Qual Life ResOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Locus coeruleus abnormalities on neuromelanin-sensitive MRI in Parkinson's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed locus coeruleus (LC) integrity on neuromelanin-sensitive MRI in Parkinson’s disease (PD), pooling independent comparisons with healthy controls using random-effects…

J NeurolOct 22, 2026Read summary
Clinical ResearchNeurologyOpen access

Efficacy and Safety of Argatroban as an Adjunct to Antiplatelet Therapy in Ischemic Stroke: An Updated Systematic Review and Meta-analysis.

This systematic review and meta-analysis assessed argatroban added to antiplatelet therapy versus control in acute ischemic stroke.

Eur J Clin PharmacolOct 22, 2026Read summary
Clinical ResearchPsychiatryOpen access

Effects of transcranial direct current stimulation on nicotine use disorder: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed transcranial direct current stimulation (tDCS) for smoking-related outcomes in people with nicotine use disorder.

Nicotine Tob ResOct 22, 2026Read summary
Case ReportRheumatologyOpen access

Avoiding Diagnostic Overshadowing: A Case Series on Cervical Myelopathy in Patients with Fibromyalgia.

Three patients referred to a multidisciplinary chronic pain clinic for fibromyalgia evaluation had substantial physical and neurological impairment.

Int Med Case Rep JOct 22, 2026Read case
Clinical ResearchEndocrinology

Evaluating Improvement in Pain and Sensory Function When Using High-Frequency (10-kHz) Spinal Cord Stimulation in Individuals With Painful Diabetic Neuropathy: A Multicenter Randomized Controlled Trial (PDN-Sensory).

The multicenter randomized controlled PDN-Sensory trial evaluated 10-kHz spinal cord stimulation (SCS) plus conventional medical management (CMM) versus CMM alone in people with painful diabetic neuropathy.

Diabetes CareOct 21, 2026Read summary
Clinical ResearchGeriatricsOpen access

Feasibility of a multidimensional interdisciplinary rehabilitation program for people with dementia and their informal primary caregivers - a randomized pilot trial with a caregiver focus.

This randomized pilot trial assessed the feasibility of a person-centred, interdisciplinary rehabilitation program for community-dwelling people with dementia that also provided education and support to informal…

BMC GeriatrOct 21, 2026Read summary
Clinical ResearchNeurologyOpen access

Real-world safety and efficacy of lecanemab in the treatment of Alzheimer's disease: a systematic review and meta-analysis.

This systematic review and meta-analysis pooled real-world studies of lecanemab treatment in people with Alzheimer’s disease, including 37 studies.

J NeurolOct 21, 2026Read summary
Case ReportPhysical Medicine & Rehabilitation

Seated Modified Liuzijue Training for Rehabilitation of a Patient with Respiratory Impairment During the Recovery Phase of Stroke: A Case Report.

A patient with respiratory impairment during stroke recovery also had motor dysfunction and balance limitations that made the traditional standing Liuzijue protocol unsuitable.

J Vis ExpOct 21, 2026Read case
Case ReportNeurology

Child Neurology: Neonatal Management of Tyrosine Hydroxylase Deficiency: How Early Is Early Enough?

Two preterm neonates from unrelated families with a known family history of tyrosine hydroxylase deficiency were diagnosed early. Both began levodopa/carbidopa treatment during the neonatal period.

NeurologyOct 20, 2026Read case
Clinical ResearchPediatricsOpen access

Levetiracetam versus valproate for new-onset or previously treated but inadequately controlled epilepsy in children: a systematic review and meta-analysis of randomized controlled trials.

This systematic review and meta-analysis compared levetiracetam with valproate in children aged 0–18 years with new-onset or inadequately controlled epilepsy.

Eur J Clin PharmacolOct 20, 2026Read summary
Clinical ResearchNeurologyOpen access

The effect of seizure-free period on seizure recurrence following antiseizure medication withdrawal: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis examined whether the duration of seizure freedom before antiseizure medication (ASM) withdrawal is associated with subsequent seizure recurrence in people with…

J NeurolOct 20, 2026Read summary
Clinical ResearchGeriatricsOpen access

Optimizing exercise prescriptions for older adults with mild cognitive impairment: a dose-response network meta-analysis of modality-dose combinations on executive function.

This Bayesian dose-response network meta-analysis synthesized randomized controlled trials of repeated exercise programmes in adults aged 60 years or older with mild cognitive impairment.

PeerJOct 20, 2026Read summary
Case ReportOncology (Medical)

A Favorable Partial Response in Patients With Glioblastoma Multiforme Following Combined [ 177 Lu]Lu-FAP-2286 and Chemotherapy.

A 64-year-old woman with IDH-wild-type, WHO grade IV glioblastoma underwent [68Ga]Ga-FAP-2286 PET/CT, which detected active tumor recurrence before definitive radiologic evidence of progression.

Clin Nucl MedOct 20, 2026Read case
Case ReportNeurology

Amyloid PET Changes During Lecanemab Treatment in Patients With and Without Amyloid-related Imaging Abnormalities.

Three patients with Alzheimer disease and similar clinical backgrounds and baseline cognitive performance underwent amyloid-β PET before and after lecanemab treatment.

Clin Nucl MedOct 20, 2026Read case
Clinical ResearchNeurology

Interventions Supporting Functional Recovery After Traumatic Brain Injury in Public Safety Personnel: A Systematic Review of Outcomes and Work Reintegration Considerations.

This systematic review synthesized evidence on interventions for functional recovery and return to work (RTW) among public safety personnel (PSP) with traumatic brain injury.

J Head Trauma RehabilOct 20, 2026Read summary
Case ReportRadiology (Diagnostic)

High-Resolution Ultrasound in the Evaluation of Median and Superficial Radial Nerve Involvement in Neurofibromatosis Type 1.

A 16-year-old girl with neurofibromatosis type 1 presented with hand pain and paresthesia. High-resolution ultrasound showed a hypervascular superficial neurofibroma, marked epineural thickening of the median nerve…

Ultrasound QOct 19, 2026Read case
Case ReportNeurologyOpen access

Delayed diagnosis of cerebrotendinous xanthomatosis with progressive neurological involvement: a case report.

A 34-year-old man with genetically confirmed cerebrotendinous xanthomatosis presented with progressive gait instability, dysarthria, dysphagia, and cognitive impairment.

Neurol SciOct 19, 2026Read case
Case ReportNeurologyOpen access

Cerebrospinal fluid positive for SARS-CoV-2 associated with neurological manifestations and proteome alterations in a multiple myeloma patient.

A 67-year-old woman with multiple myeloma and recent exposure to a person with COVID-19 developed rapidly progressive dysarthria, dysphagia, and hypoesthesia without respiratory symptoms.

Neurol SciOct 19, 2026Read case
Clinical ResearchNeurologyOpen access

Efficacy and safety of tolebrutinib in multiple sclerosis: a systematic review and meta-analysis.

This systematic review and meta-analysis assessed tolebrutinib’s efficacy and safety in multiple sclerosis, drawing on four publications covering four randomised controlled trials and one long-term extension study.

Neurol SciOct 19, 2026Read summary

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