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464 articles

September 202620

Case ReportPulmonology

Pulmonary arteriovenous malformation (PAVM) with hereditary haemorrhagic telangiectasia (HHT): a rare cause of paradoxical embolic stroke.

A woman in her 40s presented with right-sided hemiparesis, and MRI revealed a left thalamic infarction. Further investigation identified pulmonary arteriovenous malformation (PAVM) associated with hereditary…

BMJ Case RepSep 1, 2026Read case
Case ReportHematology

Systemic amyloidosis diagnosed by labial salivary gland biopsy.

A man in his 60s presented with acute decompensating heart failure and was initially evaluated for cardiac amyloidosis. Due to difficulties in obtaining a tissue sample, he was referred for a labial salivary gland…

BMJ Case RepSep 1, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Effect of a person-centered care intervention on return and sustained reengagement after treatment interruptions from HIV care in Zambia: A post-hoc analysis of a stepped-wedged cluster randomized trial.

This post-hoc analysis of a stepped-wedge cluster randomized trial evaluated a person-centered care (PCC) intervention in 24 Zambian clinics.

PLoS MedSep 1, 2026Read summary
Clinical ResearchPsychiatry

Weighted Blankets to Reduce Anxiety in Hospitalized Patients.

This randomized controlled trial evaluated the impact of a 15-pound weighted blanket on self-reported anxiety in 54 hospitalized adult patients.

Am J Crit CareSep 1, 2026Read summary
Case ReportNephrologyOpen access

Nintedanib-Associated Glomerular Endothelial Injury With Secondary Collapsing Focal Segmental Glomerulosclerosis: Potential Role of Sodium-Glucose Cotransporter 2 Inhibition.

A 69-year-old man with idiopathic pulmonary fibrosis and chronic kidney disease developed persistent nephrotic syndrome and renal dysfunction 16 months after starting nintedanib.

Nephrology (Carlton)Sep 1, 2026Read case
Clinical ResearchEndocrinologyOpen access

Effectiveness of Educational Programmes on Knowledge and Practice Related to Diabetic Foot Care Among Nurses: A Systematic Review.

This systematic review evaluated the impact of educational programmes on nurses' knowledge and practices related to diabetic foot care.

Endocrinol Diabetes MetabSep 1, 2026Read summary
Clinical ResearchPulmonologyOpen access

Efficacy and Safety of Mechanical Insufflation-Exsufflation in Invasively Ventilated Critically Ill Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the efficacy and safety of mechanical insufflation-exsufflation (MI-E) in invasively ventilated critically ill adults.

Nurs Crit CareSep 1, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Phenobarbital Versus Benzodiazepine-Based Pathways for Alcohol Withdrawal Syndrome in Critically Ill Adults: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the effectiveness of phenobarbital-based versus benzodiazepine-based pathways for treating alcohol withdrawal syndrome in critically ill adults.

PharmacotherapySep 1, 2026Read summary
Clinical ResearchGastroenterologyOpen access

Naltrexone Is Superior to Placebo for Abstinence and Craving Reduction in Alcohol-Associated Cirrhosis: NAL-CI Trial.

The NAL-CI trial evaluated the efficacy and safety of naltrexone in 100 patients with compensated alcohol-associated cirrhosis and alcohol use disorder.

Liver IntSep 1, 2026Read summary
Clinical ResearchInternal Medicine (General)Open access

Reducing Night-Time Sound Levels Through Bed-Level Quiet ICU Bundle: A Randomised Counterbalanced Crossover Study in Adult Intensive Care.

This randomized controlled trial evaluated the impact of a bed-level Quiet ICU bundle on night-time noise levels in an adult ICU in Singapore.

Nurs Crit CareSep 1, 2026Read summary
Clinical ResearchEndocrinologyOpen access

Benefits and Risks of Intensive Glucose Control in Intensive Care Units: A Meta-Analysis of Randomized Controlled Trials.

This meta-analysis of 70 randomized controlled trials involving 36,502 ICU patients compared intensive versus liberal glucose control.

Nurs Crit CareSep 1, 2026Read summary
Clinical ResearchCardiology

Bioactive phytochemicals of jasmine oil and their role in managing hypertension: A combined clinical and in-silico study.

This randomized controlled trial evaluated the effects of jasmine oil massage, both manually and with an electrical massager, on blood pressure in traffic wardens with stage 2 hypertension.

Pak J Pharm SciSep 1, 2026Read summary
Clinical ResearchNeurologyOpen access

Blood pressure parameters and cognitive decline and dementia after stroke or transient ischemic attack: results from the PROGRESS trial.

This randomized controlled trial analyzed blood pressure parameters in 5128 participants with stroke or transient ischemic attack from the PROGRESS trial.

Am J HypertensSep 1, 2026Read summary
Case ReportInternal Medicine (General)

Prolonged cholinergic toxidrome with markedly low cholinesterase activity after exposure to emamectin benzoate emulsion: A case report.

An elderly man with chronic kidney disease ingested emamectin benzoate emulsion, presenting on day 2 with abdominal pain, diarrhea, and significant sialorrhea. His serum cholinesterase levels dropped markedly to 18 U/L.

Int J Clin Pharmacol TherSep 1, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

A global overview of microsporidia infection in HIV/AIDS patients: an updated systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the prevalence and species distribution of microsporidia in HIV/AIDS patients, analyzing 39 studies from 18 countries.

Int HealthSep 1, 2026Read summary
Clinical ResearchCardiology

Mediterranean Diet Reduces Inflammation in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

This systematic review and meta-analysis evaluated the impact of the Mediterranean diet (MD) on inflammation and oxidative stress biomarkers in 3,476 adults across 33 randomized controlled trials.

Nutr RevSep 1, 2026Read summary
Clinical ResearchInternal Medicine (General)

Effects of Acute Low- and Moderate-Dose Alcohol on Chronic Disease-Related Biomarkers in Healthy Light and Heavy Drinkers.

This randomized controlled trial examined the effects of low-dose (0.35 g/kg) and moderate-dose (0.60 g/kg) alcohol on disease-related biomarkers in 32 healthy adults, both light and heavy drinkers.

Alcohol Clin Exp Res (Hoboken)Sep 1, 2026Read summary
Clinical ResearchGastroenterology

Effect of Age and Age-Defined Menopausal Status on Linaclotide Efficacy and Safety in Adults With Irritable Bowel Syndrome With Constipation or Chronic Idiopathic Constipation: Post Hoc Analyses of Phase 2b/3 Studies.

This post hoc analysis of eight randomized, placebo-controlled trials evaluated linaclotide's efficacy and safety in adults with irritable bowel syndrome with constipation (IBS-C) or chronic idiopathic constipation…

Neurogastroenterol MotilSep 1, 2026Read summary
Clinical ResearchGastroenterology

Impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluated the impact of evidence-based feeding protocols on clinical outcomes and nutritional delivery in critically ill adults.

Clin Nutr ESPENSep 1, 2026Read summary
Clinical ResearchGastroenterology

Dietary Soybean vs. Palm Oils Differ in Effects on Liver Fat in Adults With MAFLD: A 16-Week, Double-Masked, Randomized Controlled Trial.

This 16-week, double-masked randomized controlled trial compared soybean oil, rich in linoleic acid, with palm oil in adults with metabolic dysfunction-associated fatty liver disease (MAFLD).

Diabetes Obes MetabSep 1, 2026Read summary

August 20264

Clinical ResearchGastroenterologyOpen access

Proton pump inhibitors in invasively ventilated patients with SARS-CoV-2: a substudy of the re-evaluating the inhibition of stress erosions trial.

This substudy of the REVISE trial evaluated the effects of pantoprazole in 532 mechanically ventilated patients with SARS-CoV-2.

BMJ OpenAug 31, 2026Read summary
Case ReportNeurology

IgG4-related disease involving facial, infraorbital, auriculotemporal and optic nerves: multinervous cranial involvement in an adult patient.

A man in his mid-40s presented with rapidly progressive orbital symptoms initially diagnosed as orbital cellulitis. Despite treatment, his condition deteriorated, leading to multiple cranial nerve involvement.

BMJ Case RepAug 31, 2026Read case
Clinical ResearchCardiology

Blood pressure and homocysteine-lowering effects of the amlodipine/folic acid combination in patients with hypertension and serum homocysteine concentration ≥10 μmol/l (H-type hypertension): a multicenter, randomized, double-blind, parallel-controlled clinical trial.

This multicenter, randomized, double-blind, parallel-controlled trial compared amlodipine alone with amlodipine plus either 0.4 mg or 0.8 mg folic acid in 540 adults with hypertension and serum homocysteine ≥10 μmol/l.

J HypertensAug 31, 2026Read summary
Clinical ResearchCardiology

Natriuretic Peptide and Transthyretin and Their Relationship With Clinical Outcomes: Results From ATTRIBUTE-CM, a Randomized Controlled Trial.

This post hoc biomarker analysis of ATTRIBUTE-CM, a phase 3 randomized, double-blind, placebo-controlled trial, examined baseline NT-proBNP and serum transthyretin (sTTR) in 632 participants with transthyretin amyloid…

J Am Heart AssocAug 30, 2026Read summary

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