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1357 articles
November 202624
Firearm Injury Prevention Bystander Intervention for Adolescents in Shooting Sports: A Cluster Randomized Clinical Trial.
This parallel cluster randomized clinical trial evaluated a 3-session, co-developed firearm injury prevention bystander curriculum among adolescents in US 4-H Shooting Sports clubs.
Cost-effectiveness of digital health in primary care: a systematic review.
This systematic review examined the cost-effectiveness of digital health interventions compared with usual care among adults receiving primary care.
Intra-arterial tenecteplase during thrombectomy for acute ischemic stroke: the BRETIS-TNK2 trial.
The phase 3 BRETIS-TNK2 multicentre randomised trial compared intra-arterial tenecteplase during endovascular thrombectomy with thrombectomy alone in patients with large-vessel occlusion eligible for treatment within 24…
Oral Acarbose Inhibits Baseline Salivary Amylase and Blunts Early Postprandial Glycemia: Randomized Cross-Over Study.
This single-blinded, placebo-controlled randomized cross-over trial examined whether oral acarbose inhibition of salivary α-amylase affects postprandial blood glucose in 15 young, healthy women.
Patient Engagement in a Virtual Cardiac Rehabilitation Platform: Secondary Analysis of the ERA-Nudge Trial.
This secondary analysis of the pragmatic randomized ERA-Nudge trial examined engagement with a smartphone cardiac rehabilitation app among 223 patients at an urban safety-net hospital.
Safety and efficacy of cerebral embolic protection devices during TAVI: a meta-analysis and sequence analysis of trials.
This systematic review and meta-analysis of randomized trials assessed cerebral embolic protection (CEP) devices during transcatheter aortic valve implantation (TAVI).
Chest physiotherapy for pneumonia in children.
This Cochrane systematic review and meta-analysis assessed randomised trials of chest physiotherapy versus usual care in hospitalised children with pneumonia.
Acute effects of hibiscus tea versus coffee consumption before prolonged sitting on blood pressure and heart rate variability in adults: a randomized crossover trial.
This randomized crossover trial compared acute cardiovascular responses to hibiscus tea versus coffee before 3 hours of uninterrupted sitting in 24 young, healthy adults.
Impact of Particulate Matter Exposure on Neurological Health in Older Adults: A Systematic Review.
This PRISMA-guided systematic review assessed epidemiological evidence linking particulate matter (PM) exposure with neurological health in older adults.
Effectiveness of a Multicomponent Digital Therapeutic Program on Inhaled Medication Adherence in Chronic Obstructive Pulmonary Disease: Pilot Randomized Controlled Trial.
This 24-week, prospective, open-label randomized controlled pilot trial evaluated a multicomponent digital program in patients with COPD prescribed pressurized metered-dose inhalers.
Tranexamic acid for anemia in women of reproductive age: A systematic review of randomized trials.
This systematic review and meta-analysis assessed randomized trials of tranexamic acid (TXA) versus placebo or standard care for uterine bleeding in women of reproductive age.
Effects of Tai Chi combined with repetitive transcranial magnetic stimulation on sleep and emotional outcomes in older adults: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis examined randomized controlled trials of combined Tai Chi and repetitive transcranial magnetic stimulation (rTMS) for sleep and emotional outcomes in older adults.
Prevalence of Dokha use in Arabian countries: A systematic review and meta-analysis.
This systematic review and meta-analysis estimated Dokha use, a form of tobacco smoked through midwakh pipes, across populations in Arabian countries.
A Kampo medicine, kamishoyosan, ameliorates menstruation-associated symptoms in patients with premenstrual syndrome: An exploratory open-label, randomized controlled trial.
This open-label, exploratory randomized controlled trial evaluated the efficacy and safety of oral kamishoyosan (KSS) for premenstrual syndrome in 50 patients treated over three menstrual cycles.
Risk of retinal vascular occlusion following COVID-19 vaccination: A meta-analysis of nearly 15 million individuals.
This systematic review and meta-analysis assessed retinal vascular occlusion after COVID-19 vaccination using five observational studies with 14,877,781 reported participants.
Rescue treatment for medium vessel occlusion by intra-arterial tenecteplase: the RESCUE-TNK randomized clinical trial.
The RESCUE-TNK phase 2, multicentre randomised trial evaluated intra-arterial tenecteplase versus standard care in patients with acute ischaemic stroke caused by medium vessel occlusion.
Technical variation and evidence maturity in gender-affirming peritoneal vaginoplasty: a systematic review.
This systematic review examined technical approaches, indications, and evidence maturity for peritoneal vaginoplasty in gender-affirming surgery. It included 23 full-text studies and five video articles from 14 centers.
Differential rates of guideline-directed medical therapy modification in C-MIC and control patients: results from the C-MIC II trial.
This analysis of the multicentre, randomised C-MIC II trial examined whether changes in background heart failure medication influenced outcomes in ambulatory patients with chronic non-ischaemic HFrEF receiving…
Effectiveness of a Structured Post-Platelet Rich Plasma Rehabilitation Approach on Pain and Function in Subacromial Pain Syndrome: A Randomized Controlled Trial.
This randomized controlled trial evaluated whether structured rehabilitation after platelet-rich plasma (PRP) adds benefit to conventional physiotherapy for people with subacromial pain syndrome.
Cost-effectiveness of atosiban versus placebo for threatened preterm birth (APOSTEL 8 trial).
This economic evaluation alongside the multicentre randomised APOSTEL 8 trial compared atosiban with placebo for threatened preterm birth at 30+0 to 33+6 weeks’ gestation.
Immediate gastrocnemius responses to intermittent cold compression at different pressure levels in soccer players.
This randomized crossover trial examined immediate responses to intermittent cold compression (ICC) after a soccer-specific fatigue protocol in seven male collegiate soccer players.
Prognostic Value of the Preoperative Systemic Immune-Inflammation Index for Overall Survival After Surgical Resection for Gallbladder Cancer: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed whether preoperative systemic immune-inflammation index (SII) is associated with overall survival after gallbladder cancer resection.
Avascular necrosis of the femur following COVID-19: an updated systematic review.
This systematic review updated evidence on avascular necrosis (AVN) of the femoral head reported after COVID-19. Searches identified 55 studies, comprising four cross-sectional studies, six retrospective studies, and 45…
A phase 1 study of 4'-thio-2'-deoxycytidine in patients with solid tumors.
This phase 1 dose-escalation study evaluated oral 4′-thio-2′-deoxycytidine (TdCyd) in adults with advanced solid tumors. Twenty-seven patients received treatment on days 1–5 and 8–12 of 21-day cycles.
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