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495 articles

September 202624

Clinical ResearchOphthalmology

Standardized small black soybean extract improves tear film stability and dry eye-related symptoms: a 12 week randomized placebo-controlled trial.

This 12-week randomized, double-blind, placebo-controlled trial evaluated the effects of standardized small black soybean extract (SSBS) on tear film stability and dry eye symptoms in 100 adults.

Food FunctSep 21, 2026Read summary
Case ReportOphthalmology

Retinal Features and Preserved Vision in ENPP1 Deficiency: Long-Term Insights from Multimodal Imaging and Electrophysiology.

A male patient with ENPP1 deficiency underwent a comprehensive ophthalmic assessment over ten years. Despite systemic ectopic calcification, his visual acuity showed only slight decline, and multimodal imaging revealed…

Int J Mol SciSep 21, 2026Read case
Case ReportNeurology

Scalp necrosis and visual loss in giant cell arteritis: the importance of recognising atypical cutaneous clues.

A 70-year-old woman presented with left hemifacial pain and bilateral forehead skin plaques, initially diagnosed as shingles.

Pract NeurolSep 20, 2026Read case
Clinical ResearchOphthalmology

The effect of 0.1% topical ciclosporin a for 12-weeks on the ocular surface innate and adaptive immune response in dry eye disease: protocol for a randomized controlled clinical trial.

This randomized controlled trial protocol aims to evaluate the effects of 0.1% topical ciclosporin A combined with mineral oil eye drops versus mineral oil eye drops alone on the ocular surface immune response in 60…

Ann MedSep 19, 2026Read summary
Case ReportOphthalmologyOpen access

Rapid choroidal neovascularization after non-flap internal limiting membrane peeling for macular hole in a patient with AMD: a case report and literature review.

A 70-year-old female with age-related macular degeneration (AMD) underwent uncomplicated macular hole surgery involving non-flap internal limiting membrane (ILM) peeling.

BMC OphthalmolSep 18, 2026Read case
Clinical ResearchOphthalmologyOpen access

The effect of cycloplegia on corneal power and diameter measured by an auto-kerato-refractometer in presbyopic patients with type 2 diabetes mellitus: a post-hoc analysis of a randomized clinical trial.

This post-hoc analysis of a randomized controlled trial evaluated the impact of cycloplegia on corneal power and diameter in 88 presbyopic patients with type 2 diabetes.

BMC OphthalmolSep 18, 2026Read summary
Clinical ResearchOphthalmology

Algorithms for the identification of ophthalmic diseases in medico-administrative databases: A systematic review.

This systematic review evaluated algorithms for identifying key ophthalmic diseases in medico-administrative databases, analyzing 523 algorithms across various studies.

J Epidemiol Popul HealthSep 18, 2026Read summary
Case ReportOphthalmology

Chronic relapsing inflammatory optic neuropathy misdiagnosed as intermittent angle closure: a diagnostic challenge.

A woman in her 40s experienced recurrent retro-orbital pain and was initially misdiagnosed with migraine and later glaucoma due to suspected intermittent angle closure.

BMJ Case RepSep 17, 2026Read case
Clinical ResearchOncology (Medical)Open access

Fine-Tuning, Retrieval-Augmented Generation, and Hybrid Adaptation of Language Models for Clinical Decision-Making in Health Care: Systematic Review.

This systematic review evaluated the effectiveness of fine-tuning, retrieval-augmented generation (RAG), and hybrid adaptation strategies for transformer-based language models in clinical decision-making.

J Med Internet ResSep 17, 2026Read summary
Case ReportOphthalmology

Transient Endothelial Damage Following FS-LASIK Combined With Corneal Cross-Linking Surgery: Case Report.

An 18-year-old male with high myopia underwent FS-LASIK combined with corneal cross-linking. Postoperatively, he exhibited corneal edema and endothelial changes in both eyes by day 3.

Am J Case RepSep 17, 2026Read case
Case ReportMedical GeneticsOpen access

Biallelic WDR19 Variants: Systematic Analysis of Genotype-Phenotype Correlations.

Ciliopathies represent a diverse group of inherited disorders resulting from dysfunctional cilia. A rare subset is associated with biallelic variants in WDR19 , with fewer than 100 affected individuals reported…

Hum MutatSep 17, 2026Read case
Clinical ResearchOphthalmology

Endophthalmitis prevention in Refractive Lens Exchange.

This systematic review and meta-analysis evaluated intracameral vancomycin, cefuroxime, and moxifloxacin, and the added value of topical antibiotics for preventing endophthalmitis after phacoemulsification.

Arch Soc Esp Oftalmol (Engl Ed)Sep 17, 2026Read summary
Clinical ResearchOphthalmology

Preliminary Outcomes of iStent Inject vs Kahook Dual Blade Goniotomy Combined With Phacoemulsification: A Randomized Controlled Trial.

This randomized controlled trial compared the safety and efficacy of phacoemulsification combined with iStent inject (phaco-iStent) versus Kahook Dual Blade goniotomy (phaco-KDB) in 68 eyes with open-angle glaucoma or…

Med Sci MonitSep 16, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Short-term adjunctive use of a liposomal tear substitute after repeated intravitreal therapy: a randomized pilot study.

This randomized pilot study evaluated the effectiveness of a liposomal tear substitute in reducing dry eye symptoms in patients over 50 undergoing repeated intravitreal therapy.

Int OphthalmolSep 16, 2026Read summary
Case ReportMedical Genetics

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy.

An infant with prenatal clubfeet, preserved amniotic fluid and fetal movements was born at 37 + 7 weeks after breech presentation.

Clin GenetSep 16, 2026Read case
Clinical ResearchOphthalmology

Impact of Botulinum Toxin on Ocular Surface Parameters in Patients With Orbicularis Spasm: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis assessed ocular surface and corneal outcomes before and after botulinum toxin treatment in patients with orbicularis spasm, including blepharospasm and hemifacial spasm.

Am J OphthalmolSep 16, 2026Read summary
Clinical ResearchOphthalmology

Biologic Switching Strategies for Anti-Tumor Necrosis Factor Alpha Refractory Noninfectious Uveitis: Systematic Review and Meta-Analysis of Clinical Approach.

This systematic review and meta-analysis assessed biologic switching in patients with noninfectious uveitis refractory to anti-TNFα therapy.

OphthalmologySep 15, 2026Read summary
Clinical ResearchOphthalmology

Effect of Intracameral Air Injection on Corneal Endothelial Cell Loss After Phacoemulsification for Cataracts of LOCS III Nuclear Grade 4 or Higher: A Randomised Clinical Trial.

This prospective randomised clinical trial assessed intracameral air injection during phacoemulsification in patients with LOCS III nuclear grade 4 or higher cataracts.

Clin Exp OphthalmolSep 14, 2026Read summary
Case ReportOphthalmology

Intravitreal Onchocerca sp. With Concomitant Cerebral MRI Lesion: A Case Report.

A 24-year-old man from Jakarta presented with blurred vision, floaters, ocular discomfort, and headaches, unresponsive to uveitis treatment.

Am J Case RepSep 13, 2026Read case
Clinical ResearchOphthalmology

Effect of Bariatric Surgery on Improvement of Retinal Microvasculature in Patients With Obesity: A Systematic Review and Meta-Analysis.

This systematic review and meta-analysis evaluated the impact of bariatric surgery on retinal microvasculature in 283 patients with obesity.

Clin ObesSep 12, 2026Read summary
Clinical ResearchOphthalmologyOpen access

Zhangyanming Tablets for Dry Eye Disease: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Study.

This multicenter, stratified, randomized, double-blind, placebo-controlled trial evaluated Zhangyanming Tablets (ZYMT) added to 0.1% sodium hyaluronate eye drops in patients with dry eye disease.

Chin J Integr MedSep 12, 2026Read summary
Clinical ResearchOphthalmology

Visual Performance of a Refractive Extended Depth of Field Intraocular Lens in Monovision and Emmetropic Settings.

This prospective, randomized, controlled, patient- and examiner-masked single-centre trial compared bilateral implantation of a refractive extended depth-of-field intraocular lens with mini-monovision or emmetropia…

Am J OphthalmolSep 12, 2026Read summary
Clinical ResearchOphthalmology

Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery: A Systematic Review and Meta-Analysis Stratified by Graft Technique.

This systematic review and meta-analysis pooled outcomes of DSAEK and DMEK in eyes with previous glaucoma surgery. It included 22 retrospective studies comprising 943 grafts (656 DSAEK and 287 DMEK).

Am J OphthalmolSep 12, 2026Read summary
Case ReportOphthalmology

Cryptococcal scleritis mimicking scleromalacia perforans.

An elderly man with diabetes presented with progressive scleral thinning and minimal pain, initially diagnosed as scleromalacia perforans.

BMJ Case RepSep 11, 2026Read case

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