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464 articles
September 202624
Mediators of the Effect of an Educational Intervention on Health-Related Quality of Life in Patients With Heart Failure: A Causal Mediation Analysis.
This causal mediation analysis used data from a randomized controlled trial of 122 patients with heart failure to examine how an educational intervention affected health-related quality of life (HRQOL).
Access Block and Ambulance Ramping: The Canaries of the Healthcare System.
This systematic review examined factors contributing to hospital access block in Queensland, Australia, utilizing a mixed methods approach.
Vogt-Koyanagi-Harada Disease Presenting With Progressive Visual Loss and Multisystem Involvement: A Case Report.
A 55-year-old Indian man presented with a 20-day history of progressive bilateral visual loss, headache, and hearing impairment.
Are co-occurring behavioural health risk factors related to reach and efficacy of in-person versus computer-generated brief alcohol interventions? Findings from a randomized controlled trial.
This randomized controlled trial examined the impact of co-occurring behavioral health risk factors (HRFs) on the reach and efficacy of brief alcohol interventions among 961 at-risk alcohol users in a hospital setting.
Occupational Leptospirosis in Urban Sanitation: Lessons for Early Recognition and Worker Protection.
A New York City sanitation worker developed severe leptospirosis after exposure to contaminated water. His initial illness was nonspecific, and he attended multiple care settings before the infection was recognized.
Application effects of information-based health management combined with knowledge-attitude-practice health education model in hypertensive patients.
This randomized controlled trial evaluated the effects of information-based health management combined with the knowledge-attitude-practice (KAP) model in 200 hypertensive patients.
Bilingual infographics improve clinical communication and health outcomes among Latino persons with HIV: A multi-site mixed methods study with a randomized controlled trial.
This multi-site randomized controlled trial evaluated the use of bilingual infographics to improve clinical communication and health outcomes among Latino persons with HIV (LPWH).
Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial.
The EMPRESS trial is an ongoing randomized controlled trial assessing the feasibility of comparing empirical meropenem versus piperacillin/tazobactam in critically ill adults with sepsis.
Effect of Non-Soy Legumes on Lipid Profile: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
This systematic review and meta-analysis evaluated the impact of non-soy legumes on lipid profiles in randomized controlled trials.
Sex differences in the risk of metformin-associated gastrointestinal adverse events: A systematic review and meta-analysis.
This systematic review and meta-analysis examined whether sex is associated with metformin-related gastrointestinal adverse events (GIAEs).
Loss of blood pressure control after rifampin initiation: a clinically significant antihypertensive drug-drug interaction.
A man in his early 60s with well-controlled hypertension experienced a sudden increase in blood pressure two weeks after starting isoniazid-rifampin therapy for latent tuberculosis.
Risk factors for pressure ulcer development among adults undergoing surgery: a systematic review.
This systematic review examined risk factors for pressure ulcer (PU) development in adults undergoing surgery, analyzing 41 studies.
Underlying vascular and mechanical commonalities of venous leg ulcers and diabetic foot ulcers: a unified framework for management.
A patient with diabetes presented with both neuropathic and venous leg ulcers (VLUs). The case emphasized the importance of comprehensive vascular and biomechanical evaluations in managing these coexisting conditions.
Telmisartan-based monotherapy and combination regimens for blood pressure control in adults with hypertension: a systematic review, meta-analysis, and GRADE assessment.
This systematic review and meta-analysis evaluated the efficacy and safety of telmisartan-based antihypertensive regimens in adults with hypertension, analyzing 25 reports involving 6,521 participants.
Fatal Myocarditis Relapse in a Patient with Myasthenia Gravis Treated with Efgartigimod Alfa: A Case Report.
A 39-year-old woman with AChR-positive generalized myasthenia gravis and a history of inflammatory myocarditis was treated with efgartigimod after inadequate response to intravenous immunoglobulin.
Phenome- and laboratory-wide meta-analyses of sickle cell trait reveal multi-system disease associations.
This meta-analysis examined the health outcomes associated with sickle cell trait (SCT) in 4,813 individuals of African genetic ancestry.
Sanjiao acupuncture combined with abdominal massage for restless legs syndrome in maintenance hemodialysis patients: A randomized controlled trial.
This single-centre randomized controlled trial evaluated whether abdominal massage added to Sanjiao acupuncture improved restless legs syndrome (RLS) in 88 maintenance hemodialysis patients with moderate-to-severe…
Association between the Geriatric Nutritional Risk Index and the risk of readmission in older inpatients: a systematic review and meta-analysis.
This systematic review and meta-analysis examined whether the Geriatric Nutritional Risk Index (GNRI) was associated with readmission and length of stay among hospitalized patients aged 60 years or older.
Effects of intensive blood pressure control on cardio-kidney outcomes by KDIGO risk categories: a Post Hoc analysis of ACCORD-BP and SPRINT trials.
This post hoc secondary analysis of the randomized SPRINT and SPRINT-eligible ACCORD-BP trials examined cardiovascular and kidney outcomes with intensive systolic blood pressure control across low, moderate, and…
Neutralising antibodies and protection from progression to severe COVID-19: A meta-analysis.
This meta-analysis examined the relationship between vaccine-induced neutralising antibodies and protection from severe COVID-19 in individuals with SARS-CoV-2 infection.
A rare intravenous paraquat exposure presenting with novel and atypical severe clinical manifestations.
A 26-year-old male presented after self-injecting 10 mL of 24% paraquat dichloride intravenously. He exhibited severe symptoms including hematemesis, diaphoresis, and bradycardia.
Elevations in blood lactate by exogenous infusion blunts exercise-stimulated whole body lipolysis in healthy individuals: a randomized controlled trial.
This randomized controlled trial investigated the impact of elevated blood lactate on exercise-stimulated lipolysis in eight healthy individuals.
Comparison of Midline Venous Catheters Versus Peripherally Inserted Central Catheters for Intravenous Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
This systematic review and random-effects meta-analysis compared midline venous catheters (MVCs) with peripherally inserted central catheters (PICCs) for intravenous therapy in adults and children.
Study of weight loss intervention to find an effective strategy for obesity management and the TARGET of weight loss amount for reducing health disorders (SLIM-TARGET): a randomized controlled trial.
This randomized controlled trial compared standard with intensive weight-loss treatment in 294 participants with overweight or obesity and six obesity-related conditions.
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