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1003 articles

October 202624

Clinical ResearchInfectious Diseases

Safety and immunogenicity of a first-generation modified vaccinia virus Ankara-vectored SARS-CoV-2 vaccine candidate with mRNA-based booster vaccination: A phase 1 trial.

This phase 1 trial assessed safety and immune responses to the MVA-vectored SARS-CoV-2 vaccine MVA-SARS-2-S in 30 healthy, SARS-CoV-2-naive adults given two doses 28 days apart, with six-month follow-up.

Hum Vaccin ImmunotherOct 15, 2026Read summary
Clinical ResearchPediatrics

Bacterial infections and antibiotic susceptibility in children with sickle-cell anemia on malaria chemoprevention using Dihydroartemisinin-piperaquine (DP) or Sulfadoxine-pyrimethamine (SP) in Uganda.

This analysis nested within a randomized, double-blind trial assessed bacterial infections and antimicrobial resistance among Ugandan children aged 6 months to 15 years with sickle-cell anemia receiving weekly…

PLoS OneOct 15, 2026Read summary
Clinical ResearchGastroenterology

Safety, Tolerability and Antiviral Activity of GST-HG131 in Chronic Hepatitis B: A Randomized, Double-Blind Phase IIa Study.

This randomized, double-blind, placebo-controlled Phase IIa trial assessed oral GST-HG131 in 45 adults with chronic hepatitis B receiving nucleos(t)ide analogue monotherapy.

Liver IntOct 14, 2026Read summary
Clinical ResearchInfectious Diseases

Viral interference with SARS-CoV-2 during the COVID-19 pandemic: An individual participant data meta-analysis.

This individual participant data meta-analysis examined whether SARS-CoV-2 co-occurred with other respiratory viruses in ten cohort studies conducted during 2020–2024.

Epidemiol InfectOct 14, 2026Read summary
Clinical ResearchPediatrics

Prevalence and genotype distribution of norovirus and rotavirus among children under five with diarrheal infection in lower-middle-income countries after Rotavirus vaccine introduction: A systematic review and meta-analysis.

This systematic review and meta-analysis assessed norovirus and rotavirus prevalence and genotype distribution among children under five with diarrheal infection in low- and middle-income countries after rotavirus…

PLoS OneOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

The dual burden of disease: Depression among patients with multidrug resistance tuberculosis in low-income and lower- middle-income countries: A systematic review and meta-analysis.

This systematic review and random-effects meta-analysis estimated depression prevalence and examined associated factors among patients with multidrug-resistant tuberculosis (MDR-TB) in low- and lower-middle-income…

PLoS OneOct 13, 2026Read summary
Clinical ResearchPediatricsOpen access

Daily Zinc Supplementation for Infection Prevention in Children With Sickle Cell Anemia: The ZIPS-2 Randomized Clinical Trial.

The ZIPS-2 randomized, double-blind, placebo-controlled trial evaluated daily zinc for infection prevention in children aged 1 to 4.99 years with sickle cell anemia in Uganda.

JAMAOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

Safety and immunogenicity of Thailand Government Pharmaceutical Organization (GPO) produced, COVID-19 vaccine, 10 μg HXP-GPOVac: A Phase III, double-blind, randomized trial in comparison with VAXZEVRIA.

This phase III, double-blind, randomized active-controlled trial compared a single dose of Thailand-produced HXP-GPOVac with VAXZEVRIA in healthy or clinically stable Thai adults who had completed a two-dose COVID-19…

VaccineOct 13, 2026Read summary
Clinical ResearchInfectious Diseases

Epigenetic insights into anti-tuberculosis drug-induced liver injury: A systematic review of DNA methylation as a potential biomarker.

This systematic review assessed whether DNA methylation patterns are associated with susceptibility to anti-tuberculosis drug-induced liver injury (ATDILI).

Eur J PharmacolOct 13, 2026Read summary
Case ReportInfectious Diseases

Emergence of linezolid resistance associated with 23S rRNA G2576T mutations in vancomycin-resistant Enterococcus faecium during oxazolidinone therapy.

A patient developed persistent vanA-positive vancomycin-resistant Enterococcus faecium bacteremia after allogeneic hematopoietic stem cell transplantation.

J Infect ChemotherOct 13, 2026Read case
Clinical ResearchInfectious Diseases

Predictors of immunological non-response despite virological suppression in people living with HIV on antiretroviral therapy: A systematic review and meta-analysis.

This systematic review and meta-analysis examined clinical, demographic and molecular predictors of inadequate CD4+ T-cell recovery despite viral suppression on antiretroviral therapy in people living with HIV.

PLoS OneOct 12, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Dynamics and functional heterogeneity of FOXP3+ regulatory T cells in Trypanosoma cruzi infection: a systematic review.

This systematic review synthesised 27 studies of FOXP3+ regulatory T-cell (Treg) phenotype and function in human and experimental Trypanosoma cruzi infection: 9 human studies and 18 murine studies.

Inflamm ResOct 12, 2026Read summary
Case ReportInfectious Diseases

Brought with the wind: A case of melioidosis acquired in the United States presenting with multiple pulmonary nodules.

A Florida resident without recent international travel presented with fever, pleuritic chest pain, and hypoxia after severe weather.

PLoS Negl Trop DisOct 12, 2026Read case
Clinical ResearchInfectious DiseasesOpen access

Association of virulence genes with biofilm formation in clinical Enterococcus faecalis isolates: a systematic review and meta-analysis.

This systematic review and random-effects meta-analysis assessed associations between virulence gene carriage and microplate-measured biofilm formation in human clinical Enterococcus faecalis isolates.

Arch MicrobiolOct 10, 2026Read summary
Clinical ResearchInfectious Diseases

Efficacy of Tecovirimat for the Treatment of Mpox Virus Infection in Humans: Systematic Review and Meta-Analysis of Randomized Controlled Trials.

This systematic review and meta-analysis assessed tecovirimat efficacy and safety in patients with laboratory-confirmed mpox, comparing it with placebo or standard care in randomised controlled trials.

Rev Med VirolOct 9, 2026Read summary
Case ReportPulmonology

Kartagener syndrome with pulmonary mycetoma and recurrent thromboembolism: A case report.

A 27-year-old man with Kartagener syndrome and situs inversus totalis presented with worsening dyspnea, chest pain, fever, hemoptysis, and ankle swelling, against a history of deep vein thrombosis, recurrent pulmonary…

Medicine (Baltimore)Oct 9, 2026Read case
Case ReportNephrology

Peritoneal dialysis-associated peritonitis caused by Ureaplasma urealyticum: A case report.

A 41-year-old woman on continuous ambulatory peritoneal dialysis for more than 10 years developed acute abdominal pain, fever, cloudy dialysate, and neutrophilic dialysate leukocytosis.

Medicine (Baltimore)Oct 9, 2026Read case
Clinical ResearchInfectious Diseases

Self-care practices of people living with HIV and hypertension or diabetes comorbidities in low-and-middle income countries: A systematic review.

This systematic review synthesised qualitative research on self-care among people living with HIV and hypertension or diabetes in low- and middle-income countries.

PLoS OneOct 9, 2026Read summary
Clinical ResearchInfectious Diseases

Near point-of-care nucleic acid amplification tests (NPOC-NAATs) using respiratory specimens for detection of pulmonary tuberculosis.

This Cochrane systematic review and meta-analysis assessed near point-of-care nucleic acid amplification testing for pulmonary tuberculosis in adults, adolescents, and children with presumptive disease.

Cochrane Database Syst RevOct 9, 2026Read summary
Clinical ResearchInfectious Diseases

Faith-based organisations in providing HIV services within low- and middle-income countries (LMICs): a systematic review.

This systematic review assessed empirical studies of faith-based organisations (FBOs) delivering HIV services in low- and middle-income countries.

HIV Res Clin PractOct 9, 2026Read summary
Clinical ResearchInfectious DiseasesOpen access

Over-dispersion in malaria-schistosoma co-infection: insights from a meta-analytical approach and systematic review.

This systematic review and meta-analysis assessed malaria–schistosomiasis co-infection patterns in endemic settings, primarily in sub-Saharan Africa, and tested whether co-infections exceeded levels expected if the…

Infect Dis PovertyOct 9, 2026Read summary
Case ReportPulmonology

Allergic bronchopulmonary mycosis associated with Talaromyces boninensis: A case report.

A patient was evaluated for allergic bronchopulmonary mycosis (ABPM), an airway hypersensitivity disorder that can be caused by fungi other than Aspergillus.

J Infect ChemotherOct 9, 2026Read case
Case ReportInfectious Diseases

Tularemia Takes a Tropical Turn: A Rare Case of Typhoidal Tularemia in Florida.

A 36-year-old man in Florida with no significant medical history or recent travel had six months of fevers, malaise, rigors, fatigue, night sweats, and unintentional 30-pound weight loss.

Am J Case RepOct 8, 2026Read case
Case ReportInfectious DiseasesOpen access

Phaeohyphomycosis in a Solid Organ Transplant Recipient: Case Report of a New Pathogenic Species of Kirschsteiniothelia.

A 63-year-old immunocompromised recipient of a combined heart-lung transplant developed a subcutaneous thigh lesion. Surgical debridement and histopathology indicated a deep fungal infection.

MycopathologiaOct 8, 2026Read case

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