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1240 articles
October 202624
Cold and Room-Temperature Platelets in Cardiac Surgery: The CHIPS Randomized Clinical Trial.
The phase 3, multicenter, randomized CHIPS trial compared cold-stored platelets (CSPs; up to 21 days) with room-temperature platelets (RTPs; up to 7 days) in pediatric and adult patients receiving platelet transfusions…
Early Discharge Strategy Including Subcutaneous Furosemide in Hospitalized Heart Failure.
This multicenter, open-label, randomized active-controlled trial in the United Kingdom studied 172 patients hospitalized with heart failure who still required parenteral diuretics.
Effect of diet-induced plasma ceramide on human in vivo microvascular endothelial function.
This double-blind, randomized crossover trial examined whether a meal-induced rise in plasma ceramides impairs in vivo microvascular function in 23 healthy young adults.
Bee Sting-Associated Kounis Syndrome Presenting as Myocardial Infarction: A Case Report and Systematic Review with Age-Based Analysis.
A 44-year-old man presented with myocardial infarction after a probable bee sting-associated allergic reaction and was considered to have Kounis syndrome, an acute coronary syndrome linked to hypersensitivity.
Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement: A PRO-TAVI Substudy.
This post hoc substudy of the multicentre randomised PRO-TAVI trial examined whether coronary disease complexity, measured by SYNTAX score, was associated with outcomes among 466 patients with significant coronary…
Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI: A Meta-Analysis of Randomized Trials.
This frequentist meta-analysis of four multicentre randomised trials compared immediate with staged complete revascularization in 2,651 patients with STEMI and multivessel disease.
Occlusion-Focused Triage vs Very-High-Risk NSTEMI Criteria: A DIFOCCULT-3 Substudy.
This substudy of the multicenter, cluster-randomized DIFOCCULT-3 trial compared occlusion/nonocclusion (OMI/NOMI) classification with the conventional STEMI/NSTEMI framework and guideline-defined very-high-risk NSTEMI…
Blood pressure targets in adults with hypertension.
This publication is a protocol for a Cochrane intervention review, not a report of completed results. It sets out to assess lower blood pressure targets (≤ 135/85 mmHg) versus standard targets (≤ 140 to 160/90 to 100…
Robotic-assisted versus conventional coronary artery bypass grafting: a systematic review, meta-analysis, and trial sequential analysis of 39,918 patients.
This systematic review and meta-analysis compared robotic-assisted with conventional coronary artery bypass grafting (CABG) across nine observational studies involving 39,918 patients.
Effectiveness and safety of target-specific RNA-based lipid-lowering therapies: A systematic review and meta-analysis of randomized controlled trials.
This systematic review and meta-analysis of randomized controlled trials assessed the efficacy and safety of RNA-based therapies targeting PCSK9, APOC3, or ANGPTL3 in patients with hyperlipidemia or…
Food-Associated Kounis Syndrome: Clinical Spectrum and Diagnostic Considerations from a Case Report and Systematic Qualitative Synthesis of Published Cases.
The supplied abstract does not describe an individual patient’s presentation, diagnostic findings, or outcome. It reports a qualitative synthesis of published food-associated Kounis syndrome cases: 53 patients across 50…
Impact of Evolocumab on LDL-Cholesterol and Cardiovascular Outcomes in Patients With Established CVD: Systematic Review and Meta-Analysis.
This systematic review and meta-analysis pooled randomised controlled trials of evolocumab in adults with established cardiovascular disease.
Integrated management of atrial fibrillation with digital health support: a pooled analysis of individual participant data from the mAFA-II and MIRACLE-AF trials.
This pooled individual participant data analysis combined two prospective randomised trials of adults with atrial fibrillation: mAFA-II, which delivered ABC pathway care through a mobile app, and MIRACLE-AF, which used…
Assisted Reproductive Technology and Risk of Congenital Heart Defects in the Offspring: A Systematic Review and Meta-Analysis.
This systematic review and meta-analysis assessed congenital heart defect (CHD) risk in offspring conceived through assisted reproductive technology (ART) compared with spontaneous conception.
Body Mass Index, Valsartan, and Myocardial Remodeling in Early-Stage Hypertrophic Cardiomyopathy: A Secondary Analysis of the Randomized VANISH Trial.
This post hoc analysis of the randomized, multicenter VANISH trial examined BMI and cardiac remodeling in participants with early-stage hypertrophic cardiomyopathy. Of 171 participants, 52% had elevated BMI.
Pilot Randomized Trial of 2 Food Purchasing Interventions in Individuals With Hypertension in New Orleans: An American Heart Association Food Is Medicine Initiative.
This randomized pilot trial compared online and in-store food vouchers among 98 people with uncontrolled hypertension in New Orleans.
Omega-6 Polyunsaturated Fatty Acids and Peripheral Artery Disease: An Individual Participant-Level Analysis of 9 International Prospective Studies.
This multicohort individual participant-level analysis and meta-analysis examined baseline omega-6 polyunsaturated fatty acids and incident peripheral artery disease (PAD) among 137,704 participants without clinical PAD…
Balanced double aortic arch with late-onset symptoms detected on 18F-FDG PET/CT in an octogenarian with advanced prostate cancer: A case report.
An 80-year-old man with advanced prostate cancer underwent 18F-FDG PET/CT for staging. He reported dysuria and back pain for more than a year, with mild intermittent swallowing discomfort.
Kartagener syndrome with pulmonary mycetoma and recurrent thromboembolism: A case report.
A 27-year-old man with Kartagener syndrome and situs inversus totalis presented with worsening dyspnea, chest pain, fever, hemoptysis, and ankle swelling, against a history of deep vein thrombosis, recurrent pulmonary…
ST elevation in lead aVR - a marker of critical left main coronary artery stenosis: A series of case reports and literature review.
Five consecutive patients presenting with acute chest pain or cardiac arrest had ST-segment elevation of at least 1 mm in lead aVR with diffuse ST depression of at least 1 mm in six or more leads.
Axillary microaxial flow pump support for stepwise source control and bridge to durable left ventricular assist device therapy in cardiac device-related infective endocarditis.
A 53-year-old man with long-standing dilated cardiomyopathy presented with cardiac resynchronization therapy-defibrillator infection, methicillin-sensitive Staphylococcus aureus bacteremia, respiratory failure, acute…
Attributable fraction of cardiac disease following radiotherapy among breast cancer survivors: a systematic review and meta-analysis.
This systematic review and random-effects meta-analysis assessed the relationship between mean heart dose (MHD) from radiotherapy and cardiac disease among breast cancer survivors.
Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial.
This pre-specified analysis of the multicentre, randomised DECISION trial examined blinded withdrawal of long-term low-dose digoxin or placebo in patients with heart failure and reduced or mildly reduced ejection…
Sex differences in pharmacological treatment of heart failure: a meta-analysis of randomized trials.
This systematic review and meta-analysis examined sex differences in pharmacological treatment effects across randomized heart failure trials and whether women’s representation influenced estimated efficacy.
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